Science Medicine
NR565 Week 1
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Students also studied
geri more Medical Injection Techniques and Sa... Latrines Fundam
21 terms 5 terms 16 terms 66 terms
amberamond Preview Peyton_maye Preview nahomi_imartin04 Preview laur
What the drug does to the body
-3 Mechanisms of action
Pharmacodynamics • Receptor
• Enzyme
• Nonselective Interactions
-most frequently seen in relation to the metabolism of drugs
Enzymes -act as catalysts in nearly every chemical reaction that takes place in the cells
-drugs can enhance or inhibit the catalytic actions
-drugs chemically alter or physically interfere with cellular structures or there
Nonselective interactions processes
• ex: chemotherapy
-cure
-decrease in symptoms
Patient-specific plan goals -stopping or slowing the disease process
-preventing disease
-improved quality of life
, -acute
• tx active disease & sustain life
-maintenance
• focus on prevention of disease progression
-supplemental
• medication required for normal body function
-palliative
Types of drug therapy • any tx program designed to provide symptomatic relief of chronic severe pain
-supportive
• maintains integrity of body functions
-prophylactic
• prevention; immunizations, pre-procedure & postexposure antibiotics
-empiric
• clinical probability of illness that has not yet been diagnosed; administering broad
spectrum antibiotics before culture results
Idiosyncratic effects unexpected individual responses to medications
Tolerance declining response to a drug
dependence physiologic or psychologic need for a substance
-drug dependence
• a person needs a drug to function normally, abruptly stopping the drug leads to
withdrawal symptoms.
NIH: dependence vs addiction
-drug addiction
• the compulsive use of a substance, despite its negative or dangerous effects
• drug-drug
• food-drug
• additive
drug interactions
• synergistic
• antagonistic
• incompatibility
-buspirone
grapefruit juice decreases the metabolism
-nefedipine
of a number of drugs, including:
-statins
leafy dark greens
what food counters the effect of warfarin
-contain vitamin K
(antagonistic interaction)
antacids reduce effects of some drugs: thyroid replacement hormones
some antibiotics
antagonistic interaction less than the desired effect of one or both drugs
synergistic interaction sum total of effect greater than if they were given alone
common synergistic interaction to control lisinopril + HCTZ
hypertension
NR565 Week 1
Save
Students also studied
geri more Medical Injection Techniques and Sa... Latrines Fundam
21 terms 5 terms 16 terms 66 terms
amberamond Preview Peyton_maye Preview nahomi_imartin04 Preview laur
What the drug does to the body
-3 Mechanisms of action
Pharmacodynamics • Receptor
• Enzyme
• Nonselective Interactions
-most frequently seen in relation to the metabolism of drugs
Enzymes -act as catalysts in nearly every chemical reaction that takes place in the cells
-drugs can enhance or inhibit the catalytic actions
-drugs chemically alter or physically interfere with cellular structures or there
Nonselective interactions processes
• ex: chemotherapy
-cure
-decrease in symptoms
Patient-specific plan goals -stopping or slowing the disease process
-preventing disease
-improved quality of life
, -acute
• tx active disease & sustain life
-maintenance
• focus on prevention of disease progression
-supplemental
• medication required for normal body function
-palliative
Types of drug therapy • any tx program designed to provide symptomatic relief of chronic severe pain
-supportive
• maintains integrity of body functions
-prophylactic
• prevention; immunizations, pre-procedure & postexposure antibiotics
-empiric
• clinical probability of illness that has not yet been diagnosed; administering broad
spectrum antibiotics before culture results
Idiosyncratic effects unexpected individual responses to medications
Tolerance declining response to a drug
dependence physiologic or psychologic need for a substance
-drug dependence
• a person needs a drug to function normally, abruptly stopping the drug leads to
withdrawal symptoms.
NIH: dependence vs addiction
-drug addiction
• the compulsive use of a substance, despite its negative or dangerous effects
• drug-drug
• food-drug
• additive
drug interactions
• synergistic
• antagonistic
• incompatibility
-buspirone
grapefruit juice decreases the metabolism
-nefedipine
of a number of drugs, including:
-statins
leafy dark greens
what food counters the effect of warfarin
-contain vitamin K
(antagonistic interaction)
antacids reduce effects of some drugs: thyroid replacement hormones
some antibiotics
antagonistic interaction less than the desired effect of one or both drugs
synergistic interaction sum total of effect greater than if they were given alone
common synergistic interaction to control lisinopril + HCTZ
hypertension
