NSG 552 Exam 3 Review: Opioid Use Disorder Pharmacology Study Guide

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NSG 552 Exam 3 Latest
Update (Questions & Answers
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What is the mechanism of action of Naloxone? - ANSWER Pure opioid antagonist
that competes and displaces opioids receptor sites.

What medications treat opioid disorder? - ANSWER Methadone;

Buprenorphine, buprenorphine + Naloxone

What medication for opioid use disorder is used with comorbid pain? - ANSWER
Buprenorphine + Naloxone

Inappropriate use of what substance may be due to uncontrolled pain? - ANSWER
Opioids

What are the Naltrexone delivery methods? - ANSWER Tablet;

Injectable;

Implant

What is one form of Naltrexone delivery method limited to inpatient use? -
ANSWER Implant

What is the mechanism of action buprenorphine? - ANSWER Mu receptor partial
agonist for opioid withdrawal

What medication taken too soon after last opioid use increases the chances of
intense withdrawal that comes on very quickly (precipitated withdrawal)? -
ANSWER Buprenorphine

What are symptoms of opioid intoxication? - ANSWER Nausea and vomiting;

Respiratory depression;

Constipation;

Itching;

Mioisis (small pupil);

Euphoria; and

Sedation

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What withdrawal symptoms of opioids? - ANSWER Nausea and vomiting;

Diarrhea;

Dehydration;

Irritability;

Restlessness;

Yawning;

Twitching;

Increased heart rate and blood pressure;

Chills;

Increased temperature;

Rhinorrhea;

Lacrimation;

Dilated pupils

What medication is given for opioid intoxication during cardiac or respiratory
depression is a concern? - ANSWER Naloxone

What are symptoms of cocaine intoxication? - ANSWER Dilated pupils;

Headache;

Tremor;

Hyper-reflexia;

Twitching;

MI;

Nausea and vomiting;

Incontinence/ARF;

Rhabdomyolysis

What is the treatment for cocaine intoxication? - ANSWER Benzodiazepines;