Psychopharmacology3Drugs3the3Brain3And3Behavior33rd3Edition3meyer3Nursing3T
est3Bank
,Psychopharmacology3Drugs3the3Brain3And3Behavior33rd3Edition3meyer3Nursing
3Test3Bank
Test3Bank
to3accompany
Psychopharmacology,3Third3Edition
Meyer3•3Quenzer
Chapter31:3Principles3of3Pharmacology
Multiple3Choice
1. refer(s)3to3specific3molecular3changes3that3occur3when3a3drug3binds3to3a3p
articular3target3site3or3receptor,3while
are3the3resulting3widespread3alterations3in3function.
a. Drug3action;3therapeutic3effects
b. Side3effects;3drug3effects
c. Therapeutic3effects;3side3effects
d. Drug3action;3drug3effects
Answer:3d
Textbook3Reference:3Pharmacology:3The3Science3of3Drug3Action
2. After3drug3administration3has3occurred,3the3amount3of3drug3in3the3blood3that3is3fre
e3to3bind3at3specific3target3sites3is3referred3to3as
a. the3therapeutic3dose.
b. first-pass3effects.
c. bioavailability.
d. ED50.
Answer:3c
Textbook3Reference:3Pharmacokinetic3Factors3Determining3Drug3Action
3. The3specific3molecular3changes3that3occur3when3a3drug3binds3to3a3particular3targ
et3site3or3receptor3are3referred3to3as
a. drug3effects.
b. drug3action.
c. side3effects.
d. placebo3effects.
Answer:3b
Textbook3Reference:3Pharmacology:3The3Science3of3Drug3Action
4. Which3of3the3following3is3not3a3possible3explanation3for3placebo3effects?
a. Pavlovian3conditioning
b. Genetic3variation
c. Drug3competition
d. Expectation3of3outcome
Answer:3c
Textbook3Reference:3Pharmacology:3The3Science3of3Drug3Action
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5. The administration3of3oxytocin3has3been3proposed3as3a3treatment3for3autism.
a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer:3c
Textbook3Reference:3Pharmacokinetic3Factors3Determining3Drug3Action
6. Which3factor3does3not3affect3the3pharmacokinetics3of3a3drug?
a. Route3of3administration
b. Lipid3solubility
c. Depot3binding
d. Drug3action
Answer:3d
Textbook3Reference:3Pharmacokinetic3Factors3Determining3Drug3Action
7. First-pass3metabolism3occurs3when3drugs3are3taken
a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer:3a
Textbook3Reference:3Pharmacokinetic3Factors3Determining3Drug3Action
8. The3area3postrema3is3one3area3in3the3brain3where3the is3not3complete.
a. cerebrospinal3fluid
b. blood–brain3barrier
c. choroid3plexus
d. phospholipid3membrane
Answer:3b
Textbook3Reference:3Pharmacokinetic3Factors3Determining3Drug3Action
9. First-pass3metabolism3occurs3with3orally3administered3drugs3because
a. their3absorption3is3slowed3by3food.
b. drugs3absorbed3into3the3bloodstream3from3the3stomach3go3to3the3liver3on3the3wa
y3to3general3circulation.
c. drugs3must3first3survive3the3acidic3environment3of3the3stomach.
d. salivary3enzymes3in3the3mouth3begin3the3process3of3metabolism.
Answer:3b
Textbook3Reference:3Pharmacokinetic3Factors3Determining3Drug3Action
10. Toxic3substances3in3the3blood3trigger3a3vomiting3response3by3activating3the
a. blood–brain3barrier.
b. choroid3plexus.
c. area3postrema.
d. median3eminence.
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Answer:3c
Textbook3Reference:3Pharmacokinetic3Factors3Determining3Drug3Action
11. Drugs3administered3_ have3the3most3rapid3onset3of3action.
a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer:3d
Textbook3Reference:3Pharmacokinetic3Factors3Determining3Drug3Action
12. Ionization3of3a3drug3depends3on3the of3the3solution3and3the
of3the3drug.
a.3
pH;3pKa
b.3 3 pK ;3pH
a
c.3 concentration; 3lipid3solubility
d.3 pH;3concentration
Answer:3a
Textbook3Reference:3Pharmacokinetic3Factors3Determining3Drug3Action
13. The3absorption3of3a3drug3depends3on3all3of3the3following3except
a. lipid3solubility.
b. ionization.
c. body3temperature.
d. the3concentration3of3the3drug.
Answer:3c
Textbook3Reference:3Pharmacokinetic3Factors3Determining3Drug3Action
14. Drugs3that3are should3be3avoided3by3women3of3childbearing3age.
a. teratogenic
b. able3to3cross3the3placental3barrier
c. psychoactive
d. highly3lipid-soluble
Answer:3a
Textbook3Reference:3Pharmacokinetic3Factors3Determining3Drug3Action
15. Agents3that3induce3developmental3abnormalities3in3a3fetus3are3known3as
a. psychoactive3drugs.
b. illicit3drugs.
c. teratogens.
d. placental3drugs.
Answer:3c
Textbook3Reference:3Pharmacokinetic3Factors3Determining3Drug3Action
16. Depot3binding3is3said3to3occur3when3drugs
a. bind3to3their3target3sites.
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est3Bank
,Psychopharmacology3Drugs3the3Brain3And3Behavior33rd3Edition3meyer3Nursing
3Test3Bank
Test3Bank
to3accompany
Psychopharmacology,3Third3Edition
Meyer3•3Quenzer
Chapter31:3Principles3of3Pharmacology
Multiple3Choice
1. refer(s)3to3specific3molecular3changes3that3occur3when3a3drug3binds3to3a3p
articular3target3site3or3receptor,3while
are3the3resulting3widespread3alterations3in3function.
a. Drug3action;3therapeutic3effects
b. Side3effects;3drug3effects
c. Therapeutic3effects;3side3effects
d. Drug3action;3drug3effects
Answer:3d
Textbook3Reference:3Pharmacology:3The3Science3of3Drug3Action
2. After3drug3administration3has3occurred,3the3amount3of3drug3in3the3blood3that3is3fre
e3to3bind3at3specific3target3sites3is3referred3to3as
a. the3therapeutic3dose.
b. first-pass3effects.
c. bioavailability.
d. ED50.
Answer:3c
Textbook3Reference:3Pharmacokinetic3Factors3Determining3Drug3Action
3. The3specific3molecular3changes3that3occur3when3a3drug3binds3to3a3particular3targ
et3site3or3receptor3are3referred3to3as
a. drug3effects.
b. drug3action.
c. side3effects.
d. placebo3effects.
Answer:3b
Textbook3Reference:3Pharmacology:3The3Science3of3Drug3Action
4. Which3of3the3following3is3not3a3possible3explanation3for3placebo3effects?
a. Pavlovian3conditioning
b. Genetic3variation
c. Drug3competition
d. Expectation3of3outcome
Answer:3c
Textbook3Reference:3Pharmacology:3The3Science3of3Drug3Action
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,Psychopharmacology3Drugs3the3Brain3And3Behavior33rd3Edition3meyer3Nursing
3Test3Bank
5. The administration3of3oxytocin3has3been3proposed3as3a3treatment3for3autism.
a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer:3c
Textbook3Reference:3Pharmacokinetic3Factors3Determining3Drug3Action
6. Which3factor3does3not3affect3the3pharmacokinetics3of3a3drug?
a. Route3of3administration
b. Lipid3solubility
c. Depot3binding
d. Drug3action
Answer:3d
Textbook3Reference:3Pharmacokinetic3Factors3Determining3Drug3Action
7. First-pass3metabolism3occurs3when3drugs3are3taken
a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer:3a
Textbook3Reference:3Pharmacokinetic3Factors3Determining3Drug3Action
8. The3area3postrema3is3one3area3in3the3brain3where3the is3not3complete.
a. cerebrospinal3fluid
b. blood–brain3barrier
c. choroid3plexus
d. phospholipid3membrane
Answer:3b
Textbook3Reference:3Pharmacokinetic3Factors3Determining3Drug3Action
9. First-pass3metabolism3occurs3with3orally3administered3drugs3because
a. their3absorption3is3slowed3by3food.
b. drugs3absorbed3into3the3bloodstream3from3the3stomach3go3to3the3liver3on3the3wa
y3to3general3circulation.
c. drugs3must3first3survive3the3acidic3environment3of3the3stomach.
d. salivary3enzymes3in3the3mouth3begin3the3process3of3metabolism.
Answer:3b
Textbook3Reference:3Pharmacokinetic3Factors3Determining3Drug3Action
10. Toxic3substances3in3the3blood3trigger3a3vomiting3response3by3activating3the
a. blood–brain3barrier.
b. choroid3plexus.
c. area3postrema.
d. median3eminence.
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3Test3Bank
Answer:3c
Textbook3Reference:3Pharmacokinetic3Factors3Determining3Drug3Action
11. Drugs3administered3_ have3the3most3rapid3onset3of3action.
a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer:3d
Textbook3Reference:3Pharmacokinetic3Factors3Determining3Drug3Action
12. Ionization3of3a3drug3depends3on3the of3the3solution3and3the
of3the3drug.
a.3
pH;3pKa
b.3 3 pK ;3pH
a
c.3 concentration; 3lipid3solubility
d.3 pH;3concentration
Answer:3a
Textbook3Reference:3Pharmacokinetic3Factors3Determining3Drug3Action
13. The3absorption3of3a3drug3depends3on3all3of3the3following3except
a. lipid3solubility.
b. ionization.
c. body3temperature.
d. the3concentration3of3the3drug.
Answer:3c
Textbook3Reference:3Pharmacokinetic3Factors3Determining3Drug3Action
14. Drugs3that3are should3be3avoided3by3women3of3childbearing3age.
a. teratogenic
b. able3to3cross3the3placental3barrier
c. psychoactive
d. highly3lipid-soluble
Answer:3a
Textbook3Reference:3Pharmacokinetic3Factors3Determining3Drug3Action
15. Agents3that3induce3developmental3abnormalities3in3a3fetus3are3known3as
a. psychoactive3drugs.
b. illicit3drugs.
c. teratogens.
d. placental3drugs.
Answer:3c
Textbook3Reference:3Pharmacokinetic3Factors3Determining3Drug3Action
16. Depot3binding3is3said3to3occur3when3drugs
a. bind3to3their3target3sites.
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