PHA 317 Final UPDATED ACTUAL Questions and CORRECT Answers
The USP monograph states, "Pravastatin No 1 multiple choice option
sodium contains not less than 90.0 (is not
equal to 89.9%) percent and not more than
110.0 percent of the labeled amount of
pravastatin sodium (C23H35NaO7)." The
chemical analysis of a pravastatin sodium
80 mg tablet found it to contain 71.9 mg of
the chemical. Does it comply with the USP
standard?
A physician in a hospital wrote a Both ii and iv are correct 2 multiple choice options
prescription for 342.45 mg of theophylline
in 250 mL of 5%dextrose solution. The
pharmacy department of the hospital
compounded an intravenous solution
containing 340 mg of theophylline per 250
mL 5% dextrose solution. The prescribing
physician thought that his prescription was
not accurately dispensed and returned the
compounded theophylline admixture. How
would one resolve this situation?
i. The weighed amount was less than the
prescribed, so the return was warranted.
ii. The weighed amount was within the
acceptable limit of 5%, so the return was
not needed.
iii. The pharmacist always be 100% accurate
in all weighing and measurement no matter
what.
iv. A realistic practical precision is expected
during measurement of ingredient(s) on the
basis of significant figures.
,A prescription with a dose of 2 mg/kg was Using 1 kg = 2 lb was not a correct decision because it resulted in an error more than
written for a 66 lb patient. The pharmacy the acceptable limit of 5%.
technician calculated the dose and forgot
the right conversion (1 kg = 2.2 lb). Instead,
the technician used a wrong conversion
factor of 1 kg=2 lb. As the pharmacist in
1 multiple choice option
charge, one is supposed to inform the
technician regarding her mistake and find
out whether the error is within the
acceptable limit of ±5%.
There are some combination products for Only i - iii are correct 2 multiple choice options
insulin for better management of diabetes
because their onset of action, peak
glycemic effect, and duration of effect are
better than rapid-acting or short-acting or
intermediate-acting insulin. Why do
combination insulins behave differently
than other insulin products?
i. They have both amorphous and
crystalline forms of insulin.
ii. The amorphous forms of the insulin
dissolve quickly; hence exhibits its action
sooner and takes care of the peak glycemic
effect just after taking a meal.
iii. The crystalline forms of the insulin begin
dissolving later slowly which takes care of
the peak glycemic effect achieved after
taking another meal later.
iv. This is something proprietary trade
secret of the manufacturer which has
nothing to do with amorphous or
crystalline form of insulin.
It is essential not to overheat cocoa butter, Only i, ii and iv are correct 2 multiple choice options
which is used as a suppository base during
the preparation of the suppository base
during the preparation of the suppository
by fusion method. Such suppositories must
be stored in the refrigerator. Why?
i. It melts in a narrow temperature range of
340 - 360C.
ii. Overheating beyond the melting point of
stable beta form, destroys the stable beta
form.
iii. Melting above the 360C and chilling at
room temperature can stabilize the beta
form.
iv. Melting at 34.50C (not beyond 360C)
and supercooling to about 150C (i.e.
refrigerating) provides stable beta form.
, You are the drug information pharmacist in Only i, ii and iii are essential 2 multiple choice options
your state, and a few pharmacy interns are
working under your supervision. You
receive a phone call from the local hospital
emergency center regarding a case of
acetaminophen poisoning. The patient has
ingested 20 Tylenol caplets. What
information do you need to collect to
provide a better understanding of the dose
of activated charcoal needed for the
patient?
i. Time of ingestion and any prior treatment
done to the patient.
ii. Strength of the Tylenol caplets.
iii. Type of activated charcoal and its
surface area.
iv. Pharmacy that sold the Tylenol.
v. Emotional state of the patient.
A study reported in British Journal of Only i, ii and iii are correct 2 multiple choice options
Dermatology suggests that ointment is
evenly spread on the skin as compared to
creams and solutions. Ointment showed an
even spread to the applied areas. Cream,
low viscosity cream, and solution showed
poor spreading, resulting in an uneven
distribution of dose (lower dose in the
periphery). Can you explain the reasons?
i. Rapid evaporation of some of the
constituents in creams and solutions may
be contributing factors.
ii. Compositions and surfactants should be
carefully evaluated.
iii. Ointments may have surfactants to help
in spreading.
iv. Surfactants increase the contact angle to
help in spreading.
The USP monograph states, "Pravastatin No 1 multiple choice option
sodium contains not less than 90.0 (is not
equal to 89.9%) percent and not more than
110.0 percent of the labeled amount of
pravastatin sodium (C23H35NaO7)." The
chemical analysis of a pravastatin sodium
80 mg tablet found it to contain 71.9 mg of
the chemical. Does it comply with the USP
standard?
A physician in a hospital wrote a Both ii and iv are correct 2 multiple choice options
prescription for 342.45 mg of theophylline
in 250 mL of 5%dextrose solution. The
pharmacy department of the hospital
compounded an intravenous solution
containing 340 mg of theophylline per 250
mL 5% dextrose solution. The prescribing
physician thought that his prescription was
not accurately dispensed and returned the
compounded theophylline admixture. How
would one resolve this situation?
i. The weighed amount was less than the
prescribed, so the return was warranted.
ii. The weighed amount was within the
acceptable limit of 5%, so the return was
not needed.
iii. The pharmacist always be 100% accurate
in all weighing and measurement no matter
what.
iv. A realistic practical precision is expected
during measurement of ingredient(s) on the
basis of significant figures.
,A prescription with a dose of 2 mg/kg was Using 1 kg = 2 lb was not a correct decision because it resulted in an error more than
written for a 66 lb patient. The pharmacy the acceptable limit of 5%.
technician calculated the dose and forgot
the right conversion (1 kg = 2.2 lb). Instead,
the technician used a wrong conversion
factor of 1 kg=2 lb. As the pharmacist in
1 multiple choice option
charge, one is supposed to inform the
technician regarding her mistake and find
out whether the error is within the
acceptable limit of ±5%.
There are some combination products for Only i - iii are correct 2 multiple choice options
insulin for better management of diabetes
because their onset of action, peak
glycemic effect, and duration of effect are
better than rapid-acting or short-acting or
intermediate-acting insulin. Why do
combination insulins behave differently
than other insulin products?
i. They have both amorphous and
crystalline forms of insulin.
ii. The amorphous forms of the insulin
dissolve quickly; hence exhibits its action
sooner and takes care of the peak glycemic
effect just after taking a meal.
iii. The crystalline forms of the insulin begin
dissolving later slowly which takes care of
the peak glycemic effect achieved after
taking another meal later.
iv. This is something proprietary trade
secret of the manufacturer which has
nothing to do with amorphous or
crystalline form of insulin.
It is essential not to overheat cocoa butter, Only i, ii and iv are correct 2 multiple choice options
which is used as a suppository base during
the preparation of the suppository base
during the preparation of the suppository
by fusion method. Such suppositories must
be stored in the refrigerator. Why?
i. It melts in a narrow temperature range of
340 - 360C.
ii. Overheating beyond the melting point of
stable beta form, destroys the stable beta
form.
iii. Melting above the 360C and chilling at
room temperature can stabilize the beta
form.
iv. Melting at 34.50C (not beyond 360C)
and supercooling to about 150C (i.e.
refrigerating) provides stable beta form.
, You are the drug information pharmacist in Only i, ii and iii are essential 2 multiple choice options
your state, and a few pharmacy interns are
working under your supervision. You
receive a phone call from the local hospital
emergency center regarding a case of
acetaminophen poisoning. The patient has
ingested 20 Tylenol caplets. What
information do you need to collect to
provide a better understanding of the dose
of activated charcoal needed for the
patient?
i. Time of ingestion and any prior treatment
done to the patient.
ii. Strength of the Tylenol caplets.
iii. Type of activated charcoal and its
surface area.
iv. Pharmacy that sold the Tylenol.
v. Emotional state of the patient.
A study reported in British Journal of Only i, ii and iii are correct 2 multiple choice options
Dermatology suggests that ointment is
evenly spread on the skin as compared to
creams and solutions. Ointment showed an
even spread to the applied areas. Cream,
low viscosity cream, and solution showed
poor spreading, resulting in an uneven
distribution of dose (lower dose in the
periphery). Can you explain the reasons?
i. Rapid evaporation of some of the
constituents in creams and solutions may
be contributing factors.
ii. Compositions and surfactants should be
carefully evaluated.
iii. Ointments may have surfactants to help
in spreading.
iv. Surfactants increase the contact angle to
help in spreading.
