NSC 832: Variables Affecting Drug Action
Questions and Correct Answers |Already Graded
A+||Brand New Version!!!
Additive effects - correct answer -2 drugs with similar actions & same moa
Synergism/potentiation - correct answer -2 drugs with different moa that produce a greater effect
with given together
Interference - correct answer -cyp 450 inhibitor (inhibits metabolism of substrate drug) causing
drug to stay longer
Or
Cyp 450 inducer- speeds up metabolism to substrate drug causing it to not be there very long
Displacement - correct answer -displacement of drug a from protein binding site by drug b,
increases plasma levels/ effect of drug a
Antidote - correct answer -given to antagonize toxic effects of another drug
Decreased intestinal absorption - correct answer -when oral drugs combine to form unabsorbable
compound
Ex antacids and tetracycline
Placeboweffectw-wcorrect answerw-
drugwresponsewcausedwbywpsychologicwfactors,winsteadwofwspecificwdrugwaction
Tolerancew-wcorrect answer -decreasedwdrugweffectwduewtowrepeatedwdrugwexposure
Questions and Correct Answers |Already Graded
A+||Brand New Version!!!
Additive effects - correct answer -2 drugs with similar actions & same moa
Synergism/potentiation - correct answer -2 drugs with different moa that produce a greater effect
with given together
Interference - correct answer -cyp 450 inhibitor (inhibits metabolism of substrate drug) causing
drug to stay longer
Or
Cyp 450 inducer- speeds up metabolism to substrate drug causing it to not be there very long
Displacement - correct answer -displacement of drug a from protein binding site by drug b,
increases plasma levels/ effect of drug a
Antidote - correct answer -given to antagonize toxic effects of another drug
Decreased intestinal absorption - correct answer -when oral drugs combine to form unabsorbable
compound
Ex antacids and tetracycline
Placeboweffectw-wcorrect answerw-
drugwresponsewcausedwbywpsychologicwfactors,winsteadwofwspecificwdrugwaction
Tolerancew-wcorrect answer -decreasedwdrugweffectwduewtowrepeatedwdrugwexposure