TEST BANK A
TietFundament
A
O A
z als A
f
CLINICAL CHEMISTRY AND
MOLECULAR DIAGNOSTICS A
A A
7t EditioB CarA Burti
A A A A A
hn yl . s
TEST BANK A
,TietzAFundamentalsAofAClinicalAChemistryAandAMolecularADiagnosticsA7thAEditionATestABank
TableAofAcontents:
I.APrinciplesAOfALaboratoryAMedicine
ChapterA1.AClinicalAChemistrysAMolecularADiagnosticssAandALaboratoryAMedicine
ChapterA2.ASelectionAandAAnalyticalAEvaluationAofAMethodsA—AWithAStatisticalATechniques
ChapterA3.AClinicalAEvaluationAofAMethods
ChapterA4.AEvidence-BasedALaboratoryAMedicine
ChapterA5.AEstablishmentAandAUseAofAReferenceAValues
ChapterA6.ASpecimenACollectionsAProcessingsAandAOtherAPreanalyticalAVariables
ChapterA7.AQualityAManagement
II.AAnalyticalATechniquesAAndAInstrumentation
ChapterA8.APrinciplesAofABasicATechniquesAandALaboratoryASafety
ChapterA9.AOpticalATechniques
ChapterA10.AElectrochemistryAandAChemicalASensors
ChapterA11.AElectrophoresis
ChapterA12.AChromatography
ChapterA13.AMassASpectrometry
ChapterA14.AEnzymeAandARateAAnalyses
ChapterA15.AImmunochemicalATechniques
ChapterA16AAutomation
ChapterA17.APoint-of-CareAInstrumentation
III.A Analytes
ChapterA18.AAminoAAcidssAPeptidessAandAProteins
ChapterA19.ASerumAEnzymes
ChapterA20.ATumorAMarkersAandACancerAGenes
ChapterA21.AKidneyAFunctionATestsA—ACreatininesAGFRsAUreasAandAUricAAcid
ChapterA22.ACarbohydrates
ChapterA23.ALipidssALipoproteinssAApolipoproteinssAandAOtherACardiacARiskAFactors
ChapterA24.AElectrolytesAandABloodAGases
ChapterA25.AHormones
ChapterA26.A CatecholaminesAandASerotonin
ChapterA27.A VitaminssATraceAElementssANutritionalAAssessment
ChapterA28.AHemoglobinsAIronsAandABilirubin
ChapterA29.APorphyrinsAandAPorphyrias
ChapterA30.ATherapeuticADrugsAandATheirAManagement
,ChapterA31.AClinicalAToxicology
ChapterA32.A ToxicAMetals
IV.A Pathophysiology
ChapterA33.ADiabetes
ChapterA34.A CardiovascularADisease
ChapterA35.AKidneyADisease
ChapterA36.A PhysiologyAandADisordersAofAWatersAElectrolytesAandAAcid-BaseAMetabolism
ChapterA37.A LiverADisease
ChapterA38.A GastrointestinalAandAPancreaticADiseases
ChapterA39.A DisordersAofABoneAandAMineralAMetabolism
ChapterA40.A DisordersAofAtheAPituitaryAGland
ChapterA41.A DisordersAofAtheAAdrenalACortex
ChapterA42.A ThyroidADisorders
ChapterA43.A Reproduction-RelatedADisorders
ChapterA44.A PregnancyAandAPrenatalATesting
ChapterA45.A NewbornAScreeningAandAInbornAErrorsAofAMetabolism
ChapterA46.APharmacogenetics
V.A MolecularADiagnostics
ChapterA47.APrinciplesAofAMolecularABiology
ChapterA48.ANucleicAAcidATechniquesAandAApplications
ChapterA49.AGenomesAandANucleicAAcidAAlterations
, TietzAFundamentalsAofAClinicalAChemistryAandAMolecularDiagnosticssA7eABurtisATestABank
ChapterA01:AClinicalAChemistrysAMolecularADiagnosticssAandALaboratoryAMedicineTestABa
nk
MULTIPLEACHOICE
1. AnAindividualAworkingAinAaAclinicalAchemistryAlaboratoryAisAmarriedAtoAaAsalesArepresentativ
eAwhoAworksAforAaAcompanyAthatAsellsAchemistryAlaboratoryAsupplies.AWhenAtheAlaboratoryA
managerArequestsAaAlistAofAneededAsuppliessAcostAofAsuppliessAandAvendorssAthisAindividualAon
lyArecommendsAtheAspouse’sAcompanyAasAtheAvendor.AThisAisAconsideredAtoAbeAa(n): a.
accountingAissue.
b. possibleAconflictAofAinterest.
c. maintenanceAofAconfidentialityAissue.
d. problemAwithAresourceAallocation.
ANS:AB
ConcernAhasAbeenAraisedAoverAtheAinterrelationshipsAbetweenApractitionersAinAtheAmedicalAfiel
dA andAcommercialAsuppliersAofAdrugssAdevicessAequipmentsAetc.sAtoAtheAmedicalAprofession.
SimilarlysArelationshipsAhaveAbeenAscrutinizedAbetweenAclinicalAlaboratoriansAandAmanufactur
ersAandAprovidersAofAdiagnosticAequipmentAandAsupplies.ATheseAconcernsAledAtheANationalAInst
itutesAofAHealthA(NIH)AinA1995AtoArequireAofficialAinstitutionalAreviewAofAfinancialAdisclosureA
byAresearchersAandAmanagementAofAsituationsAinAwhichAdisclosureAindicatesApotentialAconflicts
AofAinterest.
DIF: 1 REF:A PageA4-5 OBJ:A6A|A7
2. AApatientAvisitsAherAphysicianAstatingAthatAherAprescribedApainkillerAisAnotAworkingAtoAreduc
eAtheApainAfollowingAherArecentAsurgery.AAAfriendAofAtheApatientAclaimsAthatAtheAsameApainki
llerA“workedAwonders”AtoAreduceAherApainAafterAtheAsameAsurgery.ATheAphysicianAstatesAtha
tAtheAdifferenceAinAtheAeffectAofAtheAdrugAmightAbeAcausedAby
sAwhichAisAstudiedAinApharmacog enetics.
a. epidemiology
b. anAinheritedAdisease
c. aAconflictAofAinterest
d. aAgeneticAvariationAinAdrug-metabolizingAenzymes
ANS:AD
PharmacogeneticsAisAtheAstudyAofAtheAgeneticAvariationAofAdrugAmetabolismAbetweenAindiv
iduals.
DIF: 1 REF:AAPageA3 OBJ:A1
3. JohnAworksAinAaAmolecularAdiagnosticsAlaboratoryAandAreceivesAaAbloodAsampleAthatAhasAth
eAnameAofAaAcloseAfriendAprintedAonAtheAbarcodedAlabel.ATheAgeneticAtestAthatAisAorderedAonAth
eAfriend’sAsampleAwouldAprovideAdiagnos
ticAinformationAaboutAaAdisorderAthatAhasAaApoorAprognosissAandAtheAtestAisAusuallyAperform
edAbyAJohn.AHeAasksAaAfellowAemployeeAtoAanalyzeAtheAsampleAforAhimAandAnotAdivulgeAthe
Aresults.AThisAethicalAissueAconcerns:
a. confidentialityAofApatientAgeneticAandAmedicalAinformation.
TietFundament
A
O A
z als A
f
CLINICAL CHEMISTRY AND
MOLECULAR DIAGNOSTICS A
A A
7t EditioB CarA Burti
A A A A A
hn yl . s
TEST BANK A
,TietzAFundamentalsAofAClinicalAChemistryAandAMolecularADiagnosticsA7thAEditionATestABank
TableAofAcontents:
I.APrinciplesAOfALaboratoryAMedicine
ChapterA1.AClinicalAChemistrysAMolecularADiagnosticssAandALaboratoryAMedicine
ChapterA2.ASelectionAandAAnalyticalAEvaluationAofAMethodsA—AWithAStatisticalATechniques
ChapterA3.AClinicalAEvaluationAofAMethods
ChapterA4.AEvidence-BasedALaboratoryAMedicine
ChapterA5.AEstablishmentAandAUseAofAReferenceAValues
ChapterA6.ASpecimenACollectionsAProcessingsAandAOtherAPreanalyticalAVariables
ChapterA7.AQualityAManagement
II.AAnalyticalATechniquesAAndAInstrumentation
ChapterA8.APrinciplesAofABasicATechniquesAandALaboratoryASafety
ChapterA9.AOpticalATechniques
ChapterA10.AElectrochemistryAandAChemicalASensors
ChapterA11.AElectrophoresis
ChapterA12.AChromatography
ChapterA13.AMassASpectrometry
ChapterA14.AEnzymeAandARateAAnalyses
ChapterA15.AImmunochemicalATechniques
ChapterA16AAutomation
ChapterA17.APoint-of-CareAInstrumentation
III.A Analytes
ChapterA18.AAminoAAcidssAPeptidessAandAProteins
ChapterA19.ASerumAEnzymes
ChapterA20.ATumorAMarkersAandACancerAGenes
ChapterA21.AKidneyAFunctionATestsA—ACreatininesAGFRsAUreasAandAUricAAcid
ChapterA22.ACarbohydrates
ChapterA23.ALipidssALipoproteinssAApolipoproteinssAandAOtherACardiacARiskAFactors
ChapterA24.AElectrolytesAandABloodAGases
ChapterA25.AHormones
ChapterA26.A CatecholaminesAandASerotonin
ChapterA27.A VitaminssATraceAElementssANutritionalAAssessment
ChapterA28.AHemoglobinsAIronsAandABilirubin
ChapterA29.APorphyrinsAandAPorphyrias
ChapterA30.ATherapeuticADrugsAandATheirAManagement
,ChapterA31.AClinicalAToxicology
ChapterA32.A ToxicAMetals
IV.A Pathophysiology
ChapterA33.ADiabetes
ChapterA34.A CardiovascularADisease
ChapterA35.AKidneyADisease
ChapterA36.A PhysiologyAandADisordersAofAWatersAElectrolytesAandAAcid-BaseAMetabolism
ChapterA37.A LiverADisease
ChapterA38.A GastrointestinalAandAPancreaticADiseases
ChapterA39.A DisordersAofABoneAandAMineralAMetabolism
ChapterA40.A DisordersAofAtheAPituitaryAGland
ChapterA41.A DisordersAofAtheAAdrenalACortex
ChapterA42.A ThyroidADisorders
ChapterA43.A Reproduction-RelatedADisorders
ChapterA44.A PregnancyAandAPrenatalATesting
ChapterA45.A NewbornAScreeningAandAInbornAErrorsAofAMetabolism
ChapterA46.APharmacogenetics
V.A MolecularADiagnostics
ChapterA47.APrinciplesAofAMolecularABiology
ChapterA48.ANucleicAAcidATechniquesAandAApplications
ChapterA49.AGenomesAandANucleicAAcidAAlterations
, TietzAFundamentalsAofAClinicalAChemistryAandAMolecularDiagnosticssA7eABurtisATestABank
ChapterA01:AClinicalAChemistrysAMolecularADiagnosticssAandALaboratoryAMedicineTestABa
nk
MULTIPLEACHOICE
1. AnAindividualAworkingAinAaAclinicalAchemistryAlaboratoryAisAmarriedAtoAaAsalesArepresentativ
eAwhoAworksAforAaAcompanyAthatAsellsAchemistryAlaboratoryAsupplies.AWhenAtheAlaboratoryA
managerArequestsAaAlistAofAneededAsuppliessAcostAofAsuppliessAandAvendorssAthisAindividualAon
lyArecommendsAtheAspouse’sAcompanyAasAtheAvendor.AThisAisAconsideredAtoAbeAa(n): a.
accountingAissue.
b. possibleAconflictAofAinterest.
c. maintenanceAofAconfidentialityAissue.
d. problemAwithAresourceAallocation.
ANS:AB
ConcernAhasAbeenAraisedAoverAtheAinterrelationshipsAbetweenApractitionersAinAtheAmedicalAfiel
dA andAcommercialAsuppliersAofAdrugssAdevicessAequipmentsAetc.sAtoAtheAmedicalAprofession.
SimilarlysArelationshipsAhaveAbeenAscrutinizedAbetweenAclinicalAlaboratoriansAandAmanufactur
ersAandAprovidersAofAdiagnosticAequipmentAandAsupplies.ATheseAconcernsAledAtheANationalAInst
itutesAofAHealthA(NIH)AinA1995AtoArequireAofficialAinstitutionalAreviewAofAfinancialAdisclosureA
byAresearchersAandAmanagementAofAsituationsAinAwhichAdisclosureAindicatesApotentialAconflicts
AofAinterest.
DIF: 1 REF:A PageA4-5 OBJ:A6A|A7
2. AApatientAvisitsAherAphysicianAstatingAthatAherAprescribedApainkillerAisAnotAworkingAtoAreduc
eAtheApainAfollowingAherArecentAsurgery.AAAfriendAofAtheApatientAclaimsAthatAtheAsameApainki
llerA“workedAwonders”AtoAreduceAherApainAafterAtheAsameAsurgery.ATheAphysicianAstatesAtha
tAtheAdifferenceAinAtheAeffectAofAtheAdrugAmightAbeAcausedAby
sAwhichAisAstudiedAinApharmacog enetics.
a. epidemiology
b. anAinheritedAdisease
c. aAconflictAofAinterest
d. aAgeneticAvariationAinAdrug-metabolizingAenzymes
ANS:AD
PharmacogeneticsAisAtheAstudyAofAtheAgeneticAvariationAofAdrugAmetabolismAbetweenAindiv
iduals.
DIF: 1 REF:AAPageA3 OBJ:A1
3. JohnAworksAinAaAmolecularAdiagnosticsAlaboratoryAandAreceivesAaAbloodAsampleAthatAhasAth
eAnameAofAaAcloseAfriendAprintedAonAtheAbarcodedAlabel.ATheAgeneticAtestAthatAisAorderedAonAth
eAfriend’sAsampleAwouldAprovideAdiagnos
ticAinformationAaboutAaAdisorderAthatAhasAaApoorAprognosissAandAtheAtestAisAusuallyAperform
edAbyAJohn.AHeAasksAaAfellowAemployeeAtoAanalyzeAtheAsampleAforAhimAandAnotAdivulgeAthe
Aresults.AThisAethicalAissueAconcerns:
a. confidentialityAofApatientAgeneticAandAmedicalAinformation.