NAPSRx CNPR exam (Revised 18th
Edition) Questions with 100% CORRECT
ANSWERS (Revised 18th Edition) |Verified |
Updated
what does a STAT order mean? - CORRECT ANSWERS a drug needed immediately and given
only once
what information does the overdosage section of the labeling provide? - CORRECT ANSWERS
signs, symptoms and treatment of acute overdoses
types of drug-drug interactions: - CORRECT ANSWERS duplication, opposition (antagonism)
and alteration (p.51)
tolerance vs resistance - CORRECT ANSWERS tolerance is the diminished response to a drug;
resistance is the cells ability to resist the effects of the drug on them.
abbreviated new drug application (ANDA) - CORRECT ANSWERS the process by which
applicants must scientifically demonstrate to the FDA that their generic product is bioequivalent to or
performs in the same way as the innovator drug, no duplicate testing (p. 75)
the Hatch-Waxman Act of 1984 - CORRECT ANSWERS -A.K.A. Drug Price Competition and
Patent Restoration Act
-made it easier to bring generic drugs to the market by requiring the FDA to only look at bioavailability
studies in order to approve an ANDA.
-gave protection to the research based manufacturers by providing a 30-month automatic cooling off
period once an ANDA is challenged for patent infringement (p. 75)
, four basic transport mechanisms - CORRECT ANSWERS passive diffusion, facilitated diffusion,
active transport, and pinocytosis (p. 95)
potency vs efficacy - CORRECT ANSWERS potency: amount of drug necessary to produce
desired effect
efficacy: magnitude of maximal response that can be received from a drug
*efficacy is almost always more important that potency* (p. 106)
the four phases of clinical trials - CORRECT ANSWERS phases I-IV (P. 124-126)
Key Parts Of A Clinical Paper (5) - CORRECT ANSWERS Abstract, Introduction, methods, results,
discussion/conclusions (p. 128-129)
reliability vs validity - CORRECT ANSWERS reliability = consistency and validity = accuracy
(p. 138; 143)
sampling error vs selection bias - CORRECT ANSWERS sampling error is unbiased and is
randomly chosen from the population.
selection bias is when the sample was specifically chosen based on particular characteristics (p.142-143)
independent vs dependent variable - CORRECT ANSWERS An independent variable is the one
that influences the variation. A dependent variable is the variable being tested and measured in a
scientific experiment (the result of applying the independent variable).
Drug Utilization Review (DUR) programs - CORRECT ANSWERS -involve retrospective
monitoring of physicians' prescribing patterns
-more than 90% of HMOs require DURs
-nowadays mostly monitors cost savings (p. 181)
Edition) Questions with 100% CORRECT
ANSWERS (Revised 18th Edition) |Verified |
Updated
what does a STAT order mean? - CORRECT ANSWERS a drug needed immediately and given
only once
what information does the overdosage section of the labeling provide? - CORRECT ANSWERS
signs, symptoms and treatment of acute overdoses
types of drug-drug interactions: - CORRECT ANSWERS duplication, opposition (antagonism)
and alteration (p.51)
tolerance vs resistance - CORRECT ANSWERS tolerance is the diminished response to a drug;
resistance is the cells ability to resist the effects of the drug on them.
abbreviated new drug application (ANDA) - CORRECT ANSWERS the process by which
applicants must scientifically demonstrate to the FDA that their generic product is bioequivalent to or
performs in the same way as the innovator drug, no duplicate testing (p. 75)
the Hatch-Waxman Act of 1984 - CORRECT ANSWERS -A.K.A. Drug Price Competition and
Patent Restoration Act
-made it easier to bring generic drugs to the market by requiring the FDA to only look at bioavailability
studies in order to approve an ANDA.
-gave protection to the research based manufacturers by providing a 30-month automatic cooling off
period once an ANDA is challenged for patent infringement (p. 75)
, four basic transport mechanisms - CORRECT ANSWERS passive diffusion, facilitated diffusion,
active transport, and pinocytosis (p. 95)
potency vs efficacy - CORRECT ANSWERS potency: amount of drug necessary to produce
desired effect
efficacy: magnitude of maximal response that can be received from a drug
*efficacy is almost always more important that potency* (p. 106)
the four phases of clinical trials - CORRECT ANSWERS phases I-IV (P. 124-126)
Key Parts Of A Clinical Paper (5) - CORRECT ANSWERS Abstract, Introduction, methods, results,
discussion/conclusions (p. 128-129)
reliability vs validity - CORRECT ANSWERS reliability = consistency and validity = accuracy
(p. 138; 143)
sampling error vs selection bias - CORRECT ANSWERS sampling error is unbiased and is
randomly chosen from the population.
selection bias is when the sample was specifically chosen based on particular characteristics (p.142-143)
independent vs dependent variable - CORRECT ANSWERS An independent variable is the one
that influences the variation. A dependent variable is the variable being tested and measured in a
scientific experiment (the result of applying the independent variable).
Drug Utilization Review (DUR) programs - CORRECT ANSWERS -involve retrospective
monitoring of physicians' prescribing patterns
-more than 90% of HMOs require DURs
-nowadays mostly monitors cost savings (p. 181)
