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NR 566 Midterm Practice Exam (2025) — 200 Questions With Correct Answers & Rationales

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This NR 566 Midterm Practice Exam includes 200 high-quality questions with correct answers and clear rationales to help you master advanced pharmacology concepts. Designed to mirror real NR 566 exam content, it covers prescribing, therapeutic decision-making, and pharmacologic management across major body systems. This comprehensive review is perfect for NP students who want to boost confidence and improve exam performance.

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NR 566 Midterm Practice Exam Most Recent Exam Complete
(2026) Exam Questions and Answers (Verified Answers) (Latest
Update) Graded A+




What pathogen is highly associated with CAP in general population? -
CORRECT ANSWER ✔✔✔✔✔ streptococcus pneumoniae



Other common pathogens with CAP - CORRECT ANSWER ✔✔✔✔✔ atypical
bacteria (mycoplasma pneumonia)

viruses (influenza, respiratory syncytial virus)



First line treatment CAP in previous healthy adults - CORRECT ANSWER
✔✔✔✔✔ Amoxicillin, doxycycline, macrolides (DAM)



Treatment of CAP in pregnancy - CORRECT ANSWER ✔✔✔✔✔ amoxicillin,
cephalosporins, erythromycin (ACE)



Treatment for mycoplasma pneumonia in the pediatric patient - CORRECT
ANSWER ✔✔✔✔✔ Macrolides (erythromycin, clarithromycin, azithromycin)



treatment of chlamydial pneumonia in infant - CORRECT ANSWER ✔✔✔✔✔
1




Erythromycin base/ethylsuccinate
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EXAMPREPMASTER

,Broad spectrum antibiotics - when to use? - CORRECT ANSWER ✔✔✔✔✔
empiric therapy

When you don't know which bacteria it is

more likely to facilitate emergence of drug-resistant organisms and
superinfections

prescribe these before culture results back

suspects patient has UTI



Narrow spectrum antibiotics - when to use? - CORRECT ANSWER ✔✔✔✔✔
When the pathogen is known

Preferred



What are empiric antibiotics? - CORRECT ANSWER ✔✔✔✔✔ Broad
Spectrum antibiotics that are given BEFORE the results are in for certain
circumstances.

Also can be prescribed when the NP believes it is a certain disease.



A)Prescription for an antibiotic for severe infection based on knowledge

B)Prescription of an antibiotic for severe infection based on clinical evaluation

C)Prescription of antibiotic for severe infection based on most likely causative
agent



When to prescribe empiric antibiotics? - CORRECT ANSWER ✔✔✔✔✔ E for
2




Emergency
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EXAMPREPMASTER

,E for enticpation

Embulatory patients



Pt has severe infxn, initiate treatment before test results available



How to treat C Diff - CORRECT ANSWER ✔✔✔✔✔ Stop taking the abx that
caused it



flagyl and vancomycin



Drug class known for all drugs in class to promote development of C diff -
CORRECT ANSWER ✔✔✔✔✔ cephalosporins (especially second or third
generations)



Penicillin's have cross-sensitivity with which drug class? - CORRECT ANSWER
✔✔✔✔✔ cephalosporins



Can you take penicillin's if pregnant? - CORRECT ANSWER ✔✔✔✔✔ Yes



Can you prescribe cephalosporins if pregnant? - CORRECT ANSWER ✔✔✔✔✔
yes



Patient education needed for cephalosporins - CORRECT ANSWER ✔✔✔✔✔
Can promote C diff, instruct patients to report increase in stool frequency
3
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EXAMPREPMASTER

, Can you prescribe tetracyclines in pregnant patients - CORRECT ANSWER
✔✔✔✔✔ No - can cause tooth staining



Patient education for tetracyclines - CORRECT ANSWER ✔✔✔✔✔
Photosensitivity. Advise patients to avoid prolonged exposure to sunlight, to wear
protective clothing, and to apply sunscreen to exposed skin/avoid tanning beds.

Instruct patients not to take this medication together with calcium supplements,
milk products, iron supplements, magnesium-containing laxatives, and most
antacids.

Advise patients to notify the provider if diarrhea occurs, as this is an indication
of potentially life-threatening superinfection of the bowel.



Macrolides patient education - CORRECT ANSWER ✔✔✔✔✔ increased risk
of Torsades due to prolonged QT



Which macrolide is ok for pregnancy? - CORRECT ANSWER ✔✔✔✔✔
erythromycin



Aminoglycosides patient education (ex. gentamicin, tobramycin, amikacin) -
CORRECT ANSWER ✔✔✔✔✔ use is associated with ototoxicity and
nephrotoxicity



Prescribing sulfonamides during pregnancy - CORRECT ANSWER ✔✔✔✔✔
not safe (especially in first trimester)- causes birth defects

if taken near term, infant can develop kernicterus (brain damage caused by too
much bilirubin)
4
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EXAMPREPMASTER

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