Test Bank For Clayton’s Basic Pharmacology for Nurses{19th Edition} By Michelle J. Willihnganz, Samuel L. Gurevitz, Bruce Clayton| All Chapters (1-48) Covered | Correct Answers with Rationals | Updated

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Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition
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By Michelle J. Willihnganz, Samuel L. Gurevitz, Bruce Clayton Com
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plete
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Clayton’s Material


Chapter 01: Drug Definitions, Standards, and Information Sources
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Willihnga nz: Clayton’s Basic Pharmacology for Nurses, 19th Edition
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MULTIPLE
CHOICE
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Which name identifies a drug listed by the US Food
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a nd Drug Administration (FDA)?
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Brand
Nonproprietary
Official
Trademark
ANS: C ss


The official name is the name under which a drug is
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listed by the FDA. The brand name, or trademark, is the
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name given to a drug by its manufacturer. The
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nonproprietary, o r generic, name is provided by the
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United States Adopted Names Council.
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DIF: Cognitive Level: Knowledge REF: p. 9 ss ss s s ss


OBJ: 1NAT: NCLEX Client Needs Category: Safe, Effective
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Ca re Environment TOP: Nursing Process Step: Assessment
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CON:
Patient Education ss




2. Which source contains information specific to nutritional supplements?
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a. USP Dictionary of USAN & International Drug Names
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b. Natural Medicines Comprehensive Database ss ss ss


c. United States Pharmacopoeia/National Formulary (USP NF)
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d. DrugmInteraction Facts ss




ANS: C ss


United States Pharmacopoeia/National Formulary contains information specific to
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nutrition al supplements. USP Dictionary of USAN & International Drug Names is a
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compilation of drug names, pronunciation guide, and possible future FDA approved
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drugs; it does not incl ude nutritional supplements. Natural Medicines Comprehensive
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Database contains
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evidence-
based information on herbal medicines and herbal combination products; it does not
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include information specific to nutritional supplements. Drug Interaction Facts contains
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comprehe nsive information on drug interaction facts; it does not include nutritional
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supplements.
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DIF: s s Cognitive Level: Knowledge REF: p. 4
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OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Int
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egrity
TOP: s s s s Nursing Process Step: Assessment ss s s s s s s CON: s s Nutrition | Patient Education ss ss s s




3. Which drug reference contains drug monographs that describe all drugs in a therapeutic class?
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a. DrugmFacts and Comparisons ss ss

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b. Drug Interaction Facts ss ss


c. Handbook on Injectable Drugs ss ss ss


d. Martindale—The Complete Drug Reference ss ss ss




ANS: A s s


Drug Facts and Comparisons contains drug monographs that describe all drugs in
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a therapeutic class. Monographs are formatted as tables to allow comparison of
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simil ar products, brand names, manufacturers, cost indices, and available dosage
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forms Online version is available.
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DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2 ss s s s s ss ss ss


OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity s s ss ss ss ss ss


TOP: Nursing Process Step: Assessment CON: Safety | Patient Education | Clinical
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Judgment
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4. Which drug reference contains monographs about virtually every single-
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entity drug available in the United States and describes therapeutic uses of drugs,
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includin g approved and unapproved uses?
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a. Martindale: The Complete Drug Reference ss ss ss ss


b. AHFS Drug Information ss ss


c. Drug Reference ss


d. Drug Facts and Comparisons ss ss ss




ANS: B s s


AHFS Drug Information contains monographs about virtually every single-
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entity drug available in the United States and describes therapeutic uses of drugs,
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including approved and unapproved uses.
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DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2 ss s s s s ss ss ss


OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity s s ss ss ss ss ss


TOP: Nursing Process Step: Planning CON: Safety | Patient Education | Clinical Judgment
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5. Which online drug reference makes available to healthcare providers and the public a
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st andard, comprehensive, up-to-date look up and downloadable resource about
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medicines?
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a. American Drug Index ss ss


b. American Hospital Formulary ss ss


c. DailyMed
d. Drug Reference ss




ANS: C ss


DailyMed makes available to healthcare providers and the public a standard,
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comprehensiv e, up-to-
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date look up and downloadable resource about medicines. The American Drug Index is
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not appropriate for patient use. The American Hospital Formulary is not appropriate
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for patie nt use. The drug reference is not appropriate for patient use.
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DIF: Cognitive Level: Knowledge REF: p. 3 | p. 4 s s s s s s ss ss ss ss


OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Int
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egrity
TOP: Nursing Process Step: Implementation
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CON: Safety | Patient Education | Clinical Judgment
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6. Which legislation authorizes the FDA to determine the safety of a drug before its marketing?
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a. Federal Food, Drug, and Cosmetic Act (1938) ss ss ss ss ss ss


b. Durham Humphrey Amendment (1952) ss ss ss

, Test s s Bank s s For Basic s s Pharma c ol ogy foTrhmeNMuarsrkeestmp1la9ctehmtoEBduityissand s s Sell s s your s s Study 4
Clayton’s Material


c. Controlled Substances Act (1970) ss ss ss


d. Kefauver Harris Drug Amendment (1962) ss ss ss ss




ANS: A s s


The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine
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the s afety of all drugs before marketing. Later amendments and acts helped tighten
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FDA control and ensure drug safety. The Durham Humphrey Amendment defines
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the kinds of drugs th at cannot be used safely without medical supervision and
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restricts their sale to prescription by a licensed practitioner. The Controlled Substances
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Act addresses only controlled substan ces and their categorization. The Kefauver Harris
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Drug Amendment ensures drug efficacy a nd greater drug safety. Drug manufacturers are
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required to prove to the FDA the effectiven ess of their products before marketing them.
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DIF: Cognitive Level: Knowledge REF: p. 5 Table ss ss s s ss ss


l.3 OBJ: 5
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NAT: NCLEX Client Needs Category: Physiological ss ss ss ss ss


Integrit y TOP: Nursing Process Step: Assessment
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CON: Safety | Patient Education | Evidence | Health Care Law
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7. Which classification does meperidine (Demerol) fall under?
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a. I
b. II
c. III
d. IV
ANS: B s s


Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may
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lead to severe psychological and physical dependence. Schedule I drugs have high
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potential for abuse and no recognized medical use. Schedule III drugs have some
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potential for abuse. U se may lead to low to moderate physical dependence or high
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psychological dependence. Sc hedule IV drugs have low potential for abuse. Use may
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lead to limited physical or psychol ogical dependence.
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DIF: Cognitive Level: Knowledge REF: p. 10
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OBJ: 2 NAT: NCLEX Client Needs Category: Safe, ss ss s s ss ss ss ss


Effective C are Environment
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TOP: Nursing Process Step: Assessment CON: Patient Education
s s s s ss s s s s s s s s s s s s | Addiction | Pain
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8. Which action would the FDA take to expedite drug development and approval for an
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outbre ak of smallpox?
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a. List smallpox as a health orphan disease.
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b. Omit the preclinical research phase. ss ss ss ss


c. Extend the clinical research phase. ss ss ss ss


d. Fast track the investigational drug. ss ss ss ss




ANS: D ss


Once the Investigational New Drug Application has been approved, the drug can receive
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h ighest priority within the agency, which is called fast tracking. A smallpox outbreak
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would become a priority concern in the world. Orphan diseases are not researched in a
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priority manner. Preclinical research is not omitted. Extending any phase of the research
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would me an a longer time to develop a vaccine. The FDA must ensure that all phases
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of the preclinic al and clinical research phase have been completed in a safe manner.
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DIF: Cognitive Level: Knowledge ss s s REF: p. 7 ss OBJ: 5 s s




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