WOUND CERTIFICATION EXAM
why is migration in wound healing delayed when wound is covered
w/ a scab? - ANSWERS-in order to create a moist envinroment,
epithelial cells secrete enzymes knwon as MMP (metallproteinases) to
lift the scab
what are the major components of partial-thickness repair include? -
ANSWERS-1. inflammatory response to injury
2. epithelial proliferation and migration (resurfacing)
3. differentiation of the epidermal layers to restore barrier fx of skin
what happens in wound healing, if wound involves dermal loss -
ANSWERS-granulation formation or connective tissue repair will
precede concurrently with reepithealization
when do you know complete healing has occured in epithelial
resurfacing or healing by regeneration? - ANSWERS-when skin
pigmenation matches the individual's normal skin tone
what must be restored in partial dermal loss in wound healing? -
ANSWERS-rete ridges/dermal papillae
what are the key components of proliferative phase? - ANSWERS-
epithealization, neoangiogenesis, and matrix deposition/collagen
synthesis
,what are the 4 major phases in full-thickness repair? - ANSWERS-1.
hemostasis (platelets degranulate and release growth factors)
2. inflammatory (leakage of neutrophils, macrophages )
3. proliferative/rebuilding (cont recruitment of growth factors,
granulation formation, contraction of wound edges, epithelial
resurfacing)
4. maturation/remodeling (collagen synthesis)
granulation tissue is often referred to as - ANSWERS-extracellular
matrix (ECM)
in full-thickness wounds, why is the new epidermis slightly thinner
than original epidermis? - ANSWERS-ret pegs that normall dip into
dermis is lacking
In chronic wounds where wound is healing by secondary intention,
why is healing delayed? - ANSWERS-hemostasis is absent, presence
of excess of proinflammartory cells where wound bed is bioburdened,
prolonged proliferative phase where granulation and wound
contraction must take place before epithealization
what are the characteristics of a chronic wound? - ANSWERS-
prolonged inflammatory phase,
cellular senescene, deficiency of growth factor receptor sites, absence
of hemostasis phase which triggers fibrin production and growth
factor release, and high level of proteases
, how does diabetes effect repair process? - ANSWERS-prolongs
inflammation, reduces collagen synthesis, decreases tensile strength,
impairs epithelial migration, compromises vasculature
how does advance age affect wound healing? - ANSWERS-dimished
proliferation of cells critical to repair, increased number of senescent
cells, diminished production of growth factors, hormonal changes,
multiple co-existing comorbidities
why is nutrition critical in wound healing? - ANSWERS-it's important
in collagen synthesis, tensile strength, immune fx
what are 6 risk factor components of Braden Scale for pressure ulcer?
- ANSWERS-sensory perception, moisture, mobility, activity,
nutrition, and shear/friction
What is the name of the organization that developed the pressure ulcer
staging? - ANSWERS-NPUAP (national pressure ulcer advisory
panel)
pathological effect of excessive pressure on soft tissue can be
attributed by 3 factors? what are they? - ANSWERS-tissue tolerance,
duration of pressure, and intensity of pressure
what are the extrinsic factors that impact pressure ulcers? -
ANSWERS-increase in moisture, friction and shearing
why is migration in wound healing delayed when wound is covered
w/ a scab? - ANSWERS-in order to create a moist envinroment,
epithelial cells secrete enzymes knwon as MMP (metallproteinases) to
lift the scab
what are the major components of partial-thickness repair include? -
ANSWERS-1. inflammatory response to injury
2. epithelial proliferation and migration (resurfacing)
3. differentiation of the epidermal layers to restore barrier fx of skin
what happens in wound healing, if wound involves dermal loss -
ANSWERS-granulation formation or connective tissue repair will
precede concurrently with reepithealization
when do you know complete healing has occured in epithelial
resurfacing or healing by regeneration? - ANSWERS-when skin
pigmenation matches the individual's normal skin tone
what must be restored in partial dermal loss in wound healing? -
ANSWERS-rete ridges/dermal papillae
what are the key components of proliferative phase? - ANSWERS-
epithealization, neoangiogenesis, and matrix deposition/collagen
synthesis
,what are the 4 major phases in full-thickness repair? - ANSWERS-1.
hemostasis (platelets degranulate and release growth factors)
2. inflammatory (leakage of neutrophils, macrophages )
3. proliferative/rebuilding (cont recruitment of growth factors,
granulation formation, contraction of wound edges, epithelial
resurfacing)
4. maturation/remodeling (collagen synthesis)
granulation tissue is often referred to as - ANSWERS-extracellular
matrix (ECM)
in full-thickness wounds, why is the new epidermis slightly thinner
than original epidermis? - ANSWERS-ret pegs that normall dip into
dermis is lacking
In chronic wounds where wound is healing by secondary intention,
why is healing delayed? - ANSWERS-hemostasis is absent, presence
of excess of proinflammartory cells where wound bed is bioburdened,
prolonged proliferative phase where granulation and wound
contraction must take place before epithealization
what are the characteristics of a chronic wound? - ANSWERS-
prolonged inflammatory phase,
cellular senescene, deficiency of growth factor receptor sites, absence
of hemostasis phase which triggers fibrin production and growth
factor release, and high level of proteases
, how does diabetes effect repair process? - ANSWERS-prolongs
inflammation, reduces collagen synthesis, decreases tensile strength,
impairs epithelial migration, compromises vasculature
how does advance age affect wound healing? - ANSWERS-dimished
proliferation of cells critical to repair, increased number of senescent
cells, diminished production of growth factors, hormonal changes,
multiple co-existing comorbidities
why is nutrition critical in wound healing? - ANSWERS-it's important
in collagen synthesis, tensile strength, immune fx
what are 6 risk factor components of Braden Scale for pressure ulcer?
- ANSWERS-sensory perception, moisture, mobility, activity,
nutrition, and shear/friction
What is the name of the organization that developed the pressure ulcer
staging? - ANSWERS-NPUAP (national pressure ulcer advisory
panel)
pathological effect of excessive pressure on soft tissue can be
attributed by 3 factors? what are they? - ANSWERS-tissue tolerance,
duration of pressure, and intensity of pressure
what are the extrinsic factors that impact pressure ulcers? -
ANSWERS-increase in moisture, friction and shearing
