UAMS BLOOD BANK EXAM 1 REVIEW UPDATED ACTUAL Questions and
CORRECT Answers
What are the two types of hemolysis and Intravascular hemolysis is more serious and involves complement destroying RBCs,
how do they differ? while extravascular hemolysis involves the removal of RBCs by the spleen and liver.
What cells are involved in cellular Macrophages and T cells.
immunity?
What is the function of T cells in the Recognize antigens and regulate the immune response.
immune response?
What is the primary function of B cells? Produce antibodies.
What is an antigen epitope? The part of an antigen that binds to an antibody and causes an immune response.
What is the difference between IgM and IgM is larger and can bind to 10 antigens, while IgG is produced more in the
IgG antibodies? secondary immune response and binds to 2 antigens.
What is the significance of zeta potential in Refers to the negative charge around RBCs that causes them to be repulsive to each
relation to RBCs? other.
What are prozone and postzone in Prozone refers to antibody excess, while postzone refers to antigen excess; either
immunological reactions? can cause false negative reactions.
What effect does centrifugation have on Increases agglutination by pushing cells closer together.
agglutination?
What does hemolysis indicate in the Indicates complement activation.
context of agglutination?
What is the ABO blood group system's The H antigen provides fucose so that A or B antigens can bind; blood type O has
relationship to H antigen? the highest concentration of H antigen.
What sugars are present in the A, B, and H A contains N-acetylgalactosamine, B contains D-galactose, and H contains L-fucose.
antigens?
Characterized by the genotype 'hh', where no H antigen is produced, resulting in no
What is the Bombay phenotype?
L-fucose sugar added to the oligosaccharide chain.
CORRECT Answers
What are the two types of hemolysis and Intravascular hemolysis is more serious and involves complement destroying RBCs,
how do they differ? while extravascular hemolysis involves the removal of RBCs by the spleen and liver.
What cells are involved in cellular Macrophages and T cells.
immunity?
What is the function of T cells in the Recognize antigens and regulate the immune response.
immune response?
What is the primary function of B cells? Produce antibodies.
What is an antigen epitope? The part of an antigen that binds to an antibody and causes an immune response.
What is the difference between IgM and IgM is larger and can bind to 10 antigens, while IgG is produced more in the
IgG antibodies? secondary immune response and binds to 2 antigens.
What is the significance of zeta potential in Refers to the negative charge around RBCs that causes them to be repulsive to each
relation to RBCs? other.
What are prozone and postzone in Prozone refers to antibody excess, while postzone refers to antigen excess; either
immunological reactions? can cause false negative reactions.
What effect does centrifugation have on Increases agglutination by pushing cells closer together.
agglutination?
What does hemolysis indicate in the Indicates complement activation.
context of agglutination?
What is the ABO blood group system's The H antigen provides fucose so that A or B antigens can bind; blood type O has
relationship to H antigen? the highest concentration of H antigen.
What sugars are present in the A, B, and H A contains N-acetylgalactosamine, B contains D-galactose, and H contains L-fucose.
antigens?
Characterized by the genotype 'hh', where no H antigen is produced, resulting in no
What is the Bombay phenotype?
L-fucose sugar added to the oligosaccharide chain.
