Immunology Exam 4 UAMS UPDATED
ACTUAL Questions and CORRECT
Answers
fetal thymus and bone marrow transplantation and administration of thymic hormones -
CORRECT ANSWER - treatment for DiGeorge anomaly
ABY reacts w/ soluble AGN; complexes precipitate in tissue - CORRECT ANSWER -
Type III
Which immunodeficiency are usually inherited dysfunctions of the immune system? -
CORRECT ANSWER - Primary Immunodeficiency diseases
secondary immunodeficiency is due to - CORRECT ANSWER - acquired
Cellulary immunity is mediated - CORRECT ANSWER - T Cells
Humoral immunity is mediated by: - CORRECT ANSWER - B cells
Primary is deficinvies are - CORRECT ANSWER - inherited
Defect in one system may cause ______ of othercomponents (Regulation disrupted) -
CORRECT ANSWER - hyperactivity
1. Relatively rare (except IgA deficiency)
2. Inherited defects of the immune system
3. Most patients present with recurrent infections - CORRECT ANSWER - Primary
immunodeficiency syndromes
, Transient hypogammaglobulinemia of infancy
X-Linked Bruton's agammaglobulinemia
IgA deficiency
Common variable immunodeficiency (CVI) - CORRECT ANSWER - Primary
Deficiencies of the B-cell
1. Prolonged low Ig levels
2. Children have problems with infections
3. Delay in Ig levels has been attributed to poor T cell help - CORRECT ANSWER -
Transient hypogammaglobulinemia of infancy
Development of B cell blocked at pro-B cell stage to pre-B cell stage
Lymphoid tissue (tonsils & adenoids) small or absent
T cells normal - CORRECT ANSWER - X-Linked Bruton's agammaglobulinemia
What enzyme is deficient in X-Linked agammaglobulinemia - CORRECT ANSWER -
Burton tyrosine kinase
What gender is prone to inheritng X-Linked agammaglobulinemia - CORRECT
ANSWER - males
Most common congenital immunodeficiency;1/500 caucasians - CORRECT ANSWER -
IgA deficiency
What is important know about IgA deficiency - CORRECT ANSWER - Important cause
of anaphylaxis following blood transfusions
Is IgA curable? Why? - CORRECT ANSWER - No, replacement therapy is not useful
because of the half-life of IgA is short.
ACTUAL Questions and CORRECT
Answers
fetal thymus and bone marrow transplantation and administration of thymic hormones -
CORRECT ANSWER - treatment for DiGeorge anomaly
ABY reacts w/ soluble AGN; complexes precipitate in tissue - CORRECT ANSWER -
Type III
Which immunodeficiency are usually inherited dysfunctions of the immune system? -
CORRECT ANSWER - Primary Immunodeficiency diseases
secondary immunodeficiency is due to - CORRECT ANSWER - acquired
Cellulary immunity is mediated - CORRECT ANSWER - T Cells
Humoral immunity is mediated by: - CORRECT ANSWER - B cells
Primary is deficinvies are - CORRECT ANSWER - inherited
Defect in one system may cause ______ of othercomponents (Regulation disrupted) -
CORRECT ANSWER - hyperactivity
1. Relatively rare (except IgA deficiency)
2. Inherited defects of the immune system
3. Most patients present with recurrent infections - CORRECT ANSWER - Primary
immunodeficiency syndromes
, Transient hypogammaglobulinemia of infancy
X-Linked Bruton's agammaglobulinemia
IgA deficiency
Common variable immunodeficiency (CVI) - CORRECT ANSWER - Primary
Deficiencies of the B-cell
1. Prolonged low Ig levels
2. Children have problems with infections
3. Delay in Ig levels has been attributed to poor T cell help - CORRECT ANSWER -
Transient hypogammaglobulinemia of infancy
Development of B cell blocked at pro-B cell stage to pre-B cell stage
Lymphoid tissue (tonsils & adenoids) small or absent
T cells normal - CORRECT ANSWER - X-Linked Bruton's agammaglobulinemia
What enzyme is deficient in X-Linked agammaglobulinemia - CORRECT ANSWER -
Burton tyrosine kinase
What gender is prone to inheritng X-Linked agammaglobulinemia - CORRECT
ANSWER - males
Most common congenital immunodeficiency;1/500 caucasians - CORRECT ANSWER -
IgA deficiency
What is important know about IgA deficiency - CORRECT ANSWER - Important cause
of anaphylaxis following blood transfusions
Is IgA curable? Why? - CORRECT ANSWER - No, replacement therapy is not useful
because of the half-life of IgA is short.
