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Karch’s Focus on Nursing Pharmacology (9th Edition) by Rebecca Tucker | Complete Test Bank with Verified Answers

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This document provides the full test bank for Karch’s Focus on Nursing Pharmacology (9th Edition) by Rebecca Tucker. It includes comprehensive chapter-by-chapter multiple-choice and alternate-format questions with accurate answers and rationales. Topics cover pharmacologic principles, drug classifications, mechanisms of action, dosage calculations, patient safety, and nursing considerations for all major body systems. Designed for nursing students and educators, this test bank supports exam preparation and clinical understanding of pharmacotherapy in practice.

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Institution
Nursing pharmacology
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Uploaded on
November 6, 2025
Number of pages
991
Written in
2025/2026
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Maggy
Frank

,Chapter 01 - Introduction to Drugs


A nurse working in radiology administers iodine to a patient who is having a computed tomography (CT)
scan. The nurse working on the oncology unit administers chemotherapy to patients who have
cancer. At the Public Health Department, a nurse administers a measles-mumps-rubella (MMR)
vaccine to a 14-month-old child as a routine immunization. Which branch of pharmacology best
describes the actions of all three nurses?


Pharmacoeconomics


Pharmacotherapeutics


Pharmacodynamics


Pharmacokinetics


Ans: B
Maggy
Frank
Response:


Pharmacology is the study of the biologic effects of chemicals. Nurses are involved with clinical
pharmacology or pharmacotherapeutics, which is a branch of pharmacology that deals with the uses of
drugs to treat, prevent, and diagnose disease. The radiology nurse is administering a drug to help
diagnose a disease. The oncology nurse is administering a drug to help treat a disease.
Pharmacoeconomics includes any costs involved in drug therapy. Pharmacodynamics involves how a
drug affects the body and pharmacokinetics is how the body acts on the body.


A physician has ordered intramuscular (IM) injections of morphine, a narcotic, every 4 hours as needed for
pain in a motor vehicle accident victim. The nurse is aware this drug has a high abuse potential.
Under what category would morphine be classified?


Schedule I


Schedule II


Schedule III


Schedule IV


Ans: B


Response:


Narcotics with a high abuse potential are classified as Schedule II drugs because of severe dependence

, liability. Schedule I drugs have high abuse potential and no accepted medical use. Schedule III drugs
have a lesser abuse potential than II and an accepted medical use. Schedule IV drugs have low abuse
potential and limited dependence liability.


When involved in phase III drug evaluation studies, what responsibilities would the nurse have?


Working with animals who are given experimental drugs


Choosing appropriate patients to be involved in the drug study


Monitoring and observing patients closely for adverse effects


Conducting research to determine effectiveness of the drug Ans: C


Response:


Maggy
Frank
Phase III studies involve use of a drug in a vast clinical population in which patients are asked to record
any symptoms they experience while taking the drugs. Nurses may be responsible for helping collect
and analyze the information to be shared with the Food and Drug Administration (FDA) but would not
conduct research independently because nurses do not prescribe medications. Use of animals in drug
testing is done in the preclinical trials. Select patients who are involved in phase II studies to participate
in studies where the participants have the disease the drug is intended to treat. These patients are
monitored closely for drug action and adverse effects. Phase I studies involve healthy human volunteers
who are usually paid for their participation. Nurses may observe for adverse effects and toxicity.


What concept is considered when generic drugs are substituted for brand name drugs?


Bioavailability


Critical concentration


Distribution


Half-life


Ans: A


Response:


Bioavailability is the portion of a dose of a drug that reaches the systemic circulation and is available
to act on body cells. Binders used in a generic drug may not be the same as those used in the brand
name drug. Therefore, the way the body breaks down and uses the drug may differ, which may
eliminate a generic drug substitution. Critical concentration is the amount of a drug that is needed to
cause a therapeutic effect and should not differ between generic and brand name medications.
Distribution is the phase of pharmacokinetics, which involves the movement of a drug to the body’s
tissues and is the

, same in generic and brand name drugs. A drug’s half-life is the time it takes for the amount of drug to
decrease to half the peak level, which should not change when substituting a generic medication.


A nurse is assessing the patient’s home medication use. After listening to the patient list current
medications, the nurse asks what priority question?


Do you take any generic medications?


Are any of these medications orphan drugs?


Are these medications safe to take during pregnancy?


Do you take any over-the-counter medications?


Ans: D


Response: Maggy
Frank
It is important for the nurse to specifically question use of over-the-counter medications because
patients may not consider them important. The patient is unlikely to know the meaning of orphan drugs
unless they too are health care providers. Safety during pregnancy, use of a generic medication, or
classification of orphan drugs are things the patient would be unable to answer but could be found in
reference books if the nurse wishes to research them.


After completing a course on pharmacology for nurses, what will the nurse know?


Everything necessary for safe and effective medication administration


Current pharmacologic therapy; the nurse will not require ongoing education for 5 years.


General drug information; the nurse can consult a drug guide for specific drug information.


The drug actions that are associated with each classification of medication Ans: C


Response:


After completing a pharmacology course nurses will have general drug information needed for safe and
effective medication administration but will need to consult a drug guide for specific drug information
before administering any medication. Pharmacology is constantly changing, with new drugs entering
the market and new uses for existing drugs identified. Continuing education in pharmacology is
essential to safe practice. Nurses tend to become familiar with the medications they administer most
often, but there will always be a need to research new drugs and also those the nurse is not familiar with
because no nurse knows all medications.

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