Questions and Answers | A+ Score
Assured
Causes of drug resistance - 🧠 ANSWER ✔✔Recent use of antibiotics
Over use of broad spectrum antibiotics
Age less than 2 years or greater than 65 years
Daycare center attendance
Exposure to young children
,Multiple medical comorbidities
Immunosuppression
True or false
Every antibiotic class has resistant organisms - 🧠 ANSWER ✔✔True
How can your identify local resistance patterns - 🧠 ANSWER ✔✔By
monitoring the antibiogram of the local laboratory
What vaccine has decreased resistance in older populations - 🧠 ANSWER
✔✔Pneumococcal vaccine
Commitment - 🧠 ANSWER ✔✔Demonstrate dedication to and
accountability for optimizing antibiotic prescribing and patient safety
Action for policy and practice - 🧠 ANSWER ✔✔Implement at least one
policy or practice to improve antibiotic prescribing assess whether it is
woking and modify as needed
,Tracking and reporting - 🧠 ANSWER ✔✔Monitor antibiotic prescribing
practices, and offer regular feedback to clinicians or have clinicians assess
their own antibiotic prescribing practices themselves
Education and expertise - 🧠 ANSWER ✔✔Provide educational resources to
clinicians and patients on antibiotic prescribing and ensure access to
needed expertise on optimizing antibiotic prescribing
Core elements of antibiotic stewardship - 🧠 ANSWER ✔✔Commitment
Action for policy and practice
Tracking and reporting
Education and expertise
Pharmacodynamics of beta-lactams (Penicillins) - 🧠 ANSWER ✔✔Inhibit
the biosynthesis of peptidoglycan bacterial cell wall
Natural penicillins are sensitive to what - 🧠 ANSWER ✔✔Streptococcus
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, Some Enterococcus
Some non-penicillinase producing Staphylococcus
Aminopenicillin sensitivity - 🧠 ANSWER ✔✔Greater activity against gram-
negative bacteria because of enhanced ability to penetrate the outer
membrane organisms
What are beta-lactams used for - 🧠 ANSWER ✔✔Gram negative urinary
and GI pathogens
•Escherichia coli, Proteus mirabilis, Salmonella, some Shigella species,
and Enterococcus faecalis; active against the common gram-negative
respiratory pathogens Moraxella catarrhalis (and Haemophilus influenzae
type B)
How do you broden the spectrum of beta lactams - 🧠 ANSWER
✔✔Combine with beta-lactamase inhibitors:
Clavulanate