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MN553 Advanced Pharmacology | 120+ Exam Questions on Diabetes, Insulin, Thyroid, Hormones | 2025/2026 | Purdue University Global

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This document contains over 120 verified exam questions and answers for Unit 5 of MN553: Advanced Pharmacology, aligned with the 2025/2026 curriculum at Purdue University Global. The material provides an in-depth review of pharmacological agents used in the treatment of diabetes mellitus, thyroid disorders, and hormonal therapies, structured in a concise Q&A format that mirrors real exam content. Key topics include: Antidiabetic agents: Mechanisms, advantages, and side effects of major drug classes such as biguanides (e.g., metformin), sulfonylureas, meglitinides, thiazolidinediones, DPP-4 inhibitors, SGLT-2 inhibitors, alpha-glucosidase inhibitors, amylin and incretin mimetics. Insulin therapies: Types (rapid, short, intermediate, long-acting), mixed insulin regimens (e.g., 70/30, 50/50, Humalog/Novolog mixes), onset/peak/duration times, side effects, and insulin use in pregnancy. Thyroid pharmacology: Diagnostic lab values for hypo- and hyperthyroidism, regulation of thyroid hormones, treatment strategies (e.g., levothyroxine, liothyronine), and pathophysiological understanding. Hormone therapy: Androgens, estrogens, their therapeutic uses, adverse reactions, and contraindications—plus monitoring requirements and clinical implications. Reproductive and endocrine pharmacology: Contraceptive-related risks, hormone replacement therapy, and erectile dysfunction drug precautions. This study resource is highly relevant for students in: Nurse Practitioner (NP) Programs Doctor of Nursing Practice (DNP) Master of Science in Nursing (MSN) PharmD programs Any clinical or academic setting requiring applied pharmacology knowledge With clinical insights and high-yield facts, this guide is excellent for preparing for unit exams, board certifications, or pharmacotherapy courses. Keywords: advanced pharmacology, MN553, diabetes medications, insulin types, metformin, sulfonylureas, DPP-4 inhibitors, SGLT-2 inhibitors, thyroid medications, levothyroxine, hyperthyroidism, hypothyroidism, hormone therapy, testosterone, estrogen, androgens, erectile dysfunction drugs, NP exam prep, nursing pharmacology, endocrine drugs, Purdue University Global

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MN553 Unit 5 2025/2026 Exam Questions
and Verified Answers | Already Graded
A+



Examples of biguonides - 🧠 ANSWER ✔✔Metformin




Fortamet




Glucophage


Biguanides MOA - 🧠 ANSWER ✔✔Activates AMP-kinase to hepatic

glucose production


Buganides advantages - 🧠 ANSWER ✔✔Weight neutral




No hypoglycemia

,Modest decline in LDL


SE of biguanides - 🧠 ANSWER ✔✔Nausea




Diarrhea




Cramps




Rarely harmful buildup of lactic acid (lactic acidosis)


Examples of sulfonylureas - 🧠 ANSWER ✔✔Glipizide (Gluctrol)




Clmepride (Amaryl)




Glyburide




Glipazide

,Sulfonylureas MOA - 🧠 ANSWER ✔✔Closes KATP channels on beta cell

plasma membranes




Insulin secretion


Examples of rapid acting insulin - 🧠 ANSWER ✔✔Lispro (Humalog)




Aspart (Novolog)




Glulisine (Apidra)


Rapid acting insulin onset - 🧠 ANSWER ✔✔About 5 minutes


Rapid acting insulin peak - 🧠 ANSWER ✔✔About 1 hour


Rapid acting insulin duration - 🧠 ANSWER ✔✔4-5 hours


Examples of short acting insulin - 🧠 ANSWER ✔✔"Regular" (Humalin)


When is Humalin sometimes used - 🧠 ANSWER ✔✔Around meal time


When ins Humalin taken - 🧠 ANSWER ✔✔About 30-45 minutes before

eating

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, When does Humalin peak - 🧠 ANSWER ✔✔3-4 hours


Humalin duration - 🧠 ANSWER ✔✔4-10 hours


Characteristics of inermediate acting insulin - 🧠 ANSWER ✔✔Normal

pressure hydrocephalus mixed with protamine




Delaying absorption




Looks cloudy and has to be mixed before it is injected


Intermediate insulin onset - 🧠 ANSWER ✔✔30 minutes to 1 hour


Intermediate insulin peak - 🧠 ANSWER ✔✔4-10 hours


Intermediate insulin duration - 🧠 ANSWER ✔✔12-24 hours


Examples of long acting insulin - 🧠 ANSWER ✔✔Glargine (Lantus)




Detemir (Levemir)

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