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MN553 Advanced Pharmacology | 130+ Exam Questions on Asthma, COPD, Vaccines, RA, Smoking Cessation | 2025/2026 | Purdue University Global

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This document includes over 130 high-quality exam questions and answers for MN553: Advanced Pharmacology, specifically covering Unit 4 content for the 2025/2026 academic year. Questions are presented in a clear, structured format and cover essential pharmacological principles and treatments for a wide range of conditions. Major focus areas include: Asthma and COPD: drug classifications (SABA, LABA, ICS, LAMA, LTRA), mechanisms of action, guideline-based treatment steps (GINA, GOLD), acute exacerbation management, and biologics. Smoking Cessation: comparison of therapies such as nicotine replacement (patch, gum), bupropion, varenicline (Chantix), and second-line agents like clonidine, with detailed precautions and contraindications. Vaccinations: live vs. inactivated vaccines, immunization schedules, contraindications in special populations (pregnancy, immunosuppressed), and vaccine-specific side effects (MMR, rotavirus, varicella, flu, hepatitis). Rheumatoid Arthritis (RA) and Gout: first-line treatments, DMARDs (methotrexate, hydroxychloroquine), NSAID usage, xanthine oxidase inhibitors, and patient-specific considerations. Osteoporosis: pathophysiology, risk factors, screening (DEXA), treatment (bisphosphonates, SERMs, denosumab), and monitoring strategies. The document is suitable for students in: MSN (Master of Science in Nursing) NP (Nurse Practitioner) Programs DNP (Doctor of Nursing Practice) PharmD or other healthcare-related graduate programs Any course requiring deep understanding of pharmacotherapeutics Its evidence-based answers and clinical relevance make this a powerful tool for study and revision ahead of exams or licensing preparation. Keywords: advanced pharmacology, MN553, asthma, COPD, SABA, LABA, ICS, LTRA, smoking cessation, nicotine replacement, bupropion, varenicline, immunizations, MMR, rotavirus, varicella, RA treatment, DMARDs, methotrexate, gout, xanthine oxidase, osteoporosis, bisphosphonates, NSAIDs, acetaminophen, corticosteroids

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Uploaded on
November 5, 2025
Number of pages
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Written in
2025/2026
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Exam (elaborations)
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MN553 Unit 4 2025/2026 Exam Questions
and Answers | A+ Score Assured



What is the atopic triad - 🧠 ANSWER ✔✔Asthma




Atopic dermatitis




Allergic rhinitis


Initial asthma treatment - 🧠 ANSWER ✔✔Bronchodilators


-SABA


Examples of SABAs - 🧠 ANSWER ✔✔Albuterol


Levalbuterol

,SABA MOA - 🧠 ANSWER ✔✔SABAs work on the smooth muscles of the

lungs. SABAs target a receptor called the beta-2 receptor in the airways.

The drug activates the beta-2 receptor, and this helps relax the muscles in

the airway. As a result, breathing improves




Bronchodilation


Step up after bronchodilator use - 🧠 ANSWER ✔✔ICS




LABA




Leukotriene antagonists


What is used for acute asthma exacerbations - 🧠 ANSWER ✔✔IV

corticosteroids




Magnesium sulfate




Oxygen

,Asthma treatment includes - 🧠 ANSWER ✔✔•Inhaled steroids


•Short-acting beta agonists (SABAs)

•Long-acting beta agonists (LABAs)

•Long-acting muscarinic antagonists (LAMAs)

•Leukotriene receptor antagonists (LTRAs)

•Theophylline

•Asthma biologics

•Immunotherapy


Examples of ICS - 🧠 ANSWER ✔✔Ciclesonide (Alvesco)




Budesonide (Plmicort




Beclomethasone dipropionate (Qvar)


ICS MOA - 🧠 ANSWER ✔✔Inhaled corticosteroids (ICS) are the most

effective controllers of asthma. They suppress inflammation mainly by




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, switching off multiple activated inflammatory genes through reversing

histone acetylation via the recruitment of histone deacetylase 2 (HDAC2).


Examples of LABAs - 🧠 ANSWER ✔✔•Advair (fluticasone

propionate/salmeterol)

•Dulera (mometasone/formoterol fumarate)

•Symbicort (budesonide/formoterol fumarate)

•Breo (fluticasone furoate/vilanterol)

Examples of Leukotriene receptor antagonists (LTRAs) - 🧠 ANSWER

✔✔•Singulair (montelukast)


•Accolate (zafirlukast)

•Zyflo (zileuton)


LABA MOA - 🧠 ANSWER ✔✔highly specific agonist for Beta2 receptors

with a prolonged duration of action (12 hours)




Inhibit mast cell mediator release, plasma exudation and may reduce

sensory nerve activation.

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