CURRENT Medical Diagnosis and
Treatment 2026
65th Edition
Author(s)Maxine A. Papadakis; Michael
W. Rabow; Kenneth R. McQuaid; Paul L.
Nadler; Erika Leemann Price
TEST BANK
Reference
Ch. 1 — Disease Prevention & Health Promotion —
Immunizations
Question Stem
A 68-year-old man with chronic obstructive pulmonary disease
(COPD) asks which pneumococcal vaccine he should receive
,today. He has not previously received any pneumococcal
vaccine. Which vaccine strategy is most appropriate?
Options
A. PPSV23 (single dose) only today.
B. PCV20 (single dose) today.
C. PCV13 followed by PPSV23 in 1 year.
D. No vaccine indicated until age 75.
Correct Answer
B
Rationales
• Correct (B): Current recommendations permit a single
dose of PCV20 for adults ≥65 years or for adults 19–64
with chronic lung disease who have not previously been
vaccinated; PCV20 provides broader serotype coverage
without immediate need for PPSV23. This aligns with
updated pneumococcal vaccination guidance summarized
in CMDT. accessmedicine.mhmedical.com
• A (incorrect): PPSV23 alone provides less comprehensive
serotype-specific immune response than PCV20 and is no
longer the preferred sole option in many adults without
prior pneumococcal vaccination.
• C (incorrect): PCV13 → PPSV23 sequencing was previous
guidance; now PCV20 can be used as a single-dose option,
so routine PCV13 first is less favored.
, • D (incorrect): Vaccination is indicated now given age ≥65
and COPD, not deferred.
Teaching Point
PCV20 can be given as a single dose in older adults or those
with chronic lung disease.
Citation (Simplified APA)
Papadakis et al. (2025). CURRENT Medical Diagnosis &
Treatment 2026 (65th Ed.). Ch. 1.
accessmedicine.mhmedical.com
2)
Reference
Ch. 1 — Disease Prevention & Health Promotion — Screening
for Colorectal Cancer
Question Stem
A 55-year-old woman with no symptoms asks about colorectal
cancer screening. She prefers noninvasive testing but wants the
most sensitive single test. What is the best recommendation?
Options
A. Annual fecal immunochemical test (FIT).
B. CT colonography every 5 years.
C. Colonoscopy every 10 years.
D. No screening until age 60.
, Correct Answer
C
Rationales
• Correct (C): Colonoscopy every 10 years provides both high
sensitivity for adenomas/cancer and the ability to remove
polyps during the same procedure; CMDT lists colonoscopy
as the most sensitive single screening test.
accessmedicine.mhmedical.com
• A (incorrect): Annual FIT is a reasonable noninvasive
option but is less sensitive than colonoscopy for detecting
advanced adenomas.
• B (incorrect): CT colonography is an alternative for patients
unable/unwilling to undergo colonoscopy but is less widely
recommended as first-line for those who accept invasive
testing.
• D (incorrect): Screening should begin at age 45–50 (per
recent guidelines) and certainly by 55; deferring to 60 is
inappropriate.
Teaching Point
Colonoscopy every 10 years is the most sensitive single
screening option for average-risk adults.
Citation (Simplified APA)
Papadakis et al. (2025). CURRENT Medical Diagnosis &
Treatment 2026 (65th Ed.). Ch. 1.
accessmedicine.mhmedical.com
Treatment 2026
65th Edition
Author(s)Maxine A. Papadakis; Michael
W. Rabow; Kenneth R. McQuaid; Paul L.
Nadler; Erika Leemann Price
TEST BANK
Reference
Ch. 1 — Disease Prevention & Health Promotion —
Immunizations
Question Stem
A 68-year-old man with chronic obstructive pulmonary disease
(COPD) asks which pneumococcal vaccine he should receive
,today. He has not previously received any pneumococcal
vaccine. Which vaccine strategy is most appropriate?
Options
A. PPSV23 (single dose) only today.
B. PCV20 (single dose) today.
C. PCV13 followed by PPSV23 in 1 year.
D. No vaccine indicated until age 75.
Correct Answer
B
Rationales
• Correct (B): Current recommendations permit a single
dose of PCV20 for adults ≥65 years or for adults 19–64
with chronic lung disease who have not previously been
vaccinated; PCV20 provides broader serotype coverage
without immediate need for PPSV23. This aligns with
updated pneumococcal vaccination guidance summarized
in CMDT. accessmedicine.mhmedical.com
• A (incorrect): PPSV23 alone provides less comprehensive
serotype-specific immune response than PCV20 and is no
longer the preferred sole option in many adults without
prior pneumococcal vaccination.
• C (incorrect): PCV13 → PPSV23 sequencing was previous
guidance; now PCV20 can be used as a single-dose option,
so routine PCV13 first is less favored.
, • D (incorrect): Vaccination is indicated now given age ≥65
and COPD, not deferred.
Teaching Point
PCV20 can be given as a single dose in older adults or those
with chronic lung disease.
Citation (Simplified APA)
Papadakis et al. (2025). CURRENT Medical Diagnosis &
Treatment 2026 (65th Ed.). Ch. 1.
accessmedicine.mhmedical.com
2)
Reference
Ch. 1 — Disease Prevention & Health Promotion — Screening
for Colorectal Cancer
Question Stem
A 55-year-old woman with no symptoms asks about colorectal
cancer screening. She prefers noninvasive testing but wants the
most sensitive single test. What is the best recommendation?
Options
A. Annual fecal immunochemical test (FIT).
B. CT colonography every 5 years.
C. Colonoscopy every 10 years.
D. No screening until age 60.
, Correct Answer
C
Rationales
• Correct (C): Colonoscopy every 10 years provides both high
sensitivity for adenomas/cancer and the ability to remove
polyps during the same procedure; CMDT lists colonoscopy
as the most sensitive single screening test.
accessmedicine.mhmedical.com
• A (incorrect): Annual FIT is a reasonable noninvasive
option but is less sensitive than colonoscopy for detecting
advanced adenomas.
• B (incorrect): CT colonography is an alternative for patients
unable/unwilling to undergo colonoscopy but is less widely
recommended as first-line for those who accept invasive
testing.
• D (incorrect): Screening should begin at age 45–50 (per
recent guidelines) and certainly by 55; deferring to 60 is
inappropriate.
Teaching Point
Colonoscopy every 10 years is the most sensitive single
screening option for average-risk adults.
Citation (Simplified APA)
Papadakis et al. (2025). CURRENT Medical Diagnosis &
Treatment 2026 (65th Ed.). Ch. 1.
accessmedicine.mhmedical.com
