CURRENT Medical Diagnosis and
Treatment 2026
65th Edition
Author(s)Maxine A. Papadakis; Michael
W. Rabow; Kenneth R. McQuaid; Paul L.
Nadler; Erika Leemann Price
TEST BANK
Reference
Ch. 1 — Disease Prevention & Health Promotion — Preventive
Screening Priorities. accessmedicine.mhmedical.com
Question Stem
A 52-year-old man with no significant past medical history asks
which age-based screening he should prioritize next. He has no
symptoms, a normal physical exam, and no family history of
,cancer. Which screening should you recommend first based on
highest yield for asymptomatic adults in this age group?
A. Low-dose CT scan for lung cancer
B. Colonoscopy (or other guideline-appropriate colorectal
screening)
C. Prostate-specific antigen (PSA) testing
D. Routine brain MRI
Correct Answer
B
Rationales
• Correct (B): Colorectal cancer screening is a high-yield,
age-based preventive priority for adults beginning in mid-
adulthood and remains a core preventive measure for
asymptomatic adults in this age group. CMDT emphasizes
colorectal screening as a primary prevention/screening
priority. accessmedicine.mhmedical.com
• A (incorrect): Low-dose CT is recommended only for
selected adults with a substantial smoking history; it is not
a general screening for all 52-year-olds.
accessmedicine.mhmedical.com
• C (incorrect): PSA testing is individualized and guided by
shared decision-making given harms/benefits; it is not
uniformly first-line for asymptomatic men without risk
factors. accessmedicine.mhmedical.com
, • D (incorrect): Routine brain MRI is not a screening test for
asymptomatic adults and has negligible yield and high
cost/false positives. accessmedicine.mhmedical.com
Teaching Point
Prioritize evidence-based, age-specific screenings (e.g.,
colorectal) for asymptomatic adults.
Citation (Simplified APA)
Papadakis et al. (2025). CURRENT Medical Diagnosis &
Treatment 2026 (65th Ed.). Ch. 1.
2)
Reference
Ch. 1 — Disease Prevention & Health Promotion —
Immunizations & Adult Vaccination.
accessmedicine.mhmedical.com
Question Stem
A 67-year-old woman with well-controlled type 2 diabetes
presents for a routine visit. Which immunization provides the
most immediate, evidence-based reduction in her risk for
severe disease and is recommended for virtually all adults in
this age group?
A. Live attenuated influenza vaccine (LAIV) by intranasal route
B. Herpes zoster recombinant subunit vaccine (Shingrix)
C. BCG (Bacillus Calmette–Guérin) vaccine
D. Routine booster for varicella (chickenpox) vaccine
, Correct Answer
B
Rationales
• Correct (B): Recombinant zoster vaccine is recommended
for older adults (typically ≥50 years) to prevent shingles
and postherpetic neuralgia; CMDT highlights zoster
vaccination as high-value prevention in older adults.
accessmedicine.mhmedical.com
• A (incorrect): Influenza vaccination is recommended
annually; however, LAIV (intranasal) is generally not
preferred for older adults—an inactivated formulation is
standard. accessmedicine.mhmedical.com
• C (incorrect): BCG is not indicated for routine prevention of
disease in US older adults and would not reduce risk of
common vaccine-preventable illnesses in this patient.
accessmedicine.mhmedical.com
• D (incorrect): Most older adults have natural immunity to
varicella; routine booster varicella is not a standard adult
recommendation unless lacking immunity.
accessmedicine.mhmedical.com
Teaching Point
Recombinant zoster vaccine prevents shingles and is strongly
recommended for older adults.
Treatment 2026
65th Edition
Author(s)Maxine A. Papadakis; Michael
W. Rabow; Kenneth R. McQuaid; Paul L.
Nadler; Erika Leemann Price
TEST BANK
Reference
Ch. 1 — Disease Prevention & Health Promotion — Preventive
Screening Priorities. accessmedicine.mhmedical.com
Question Stem
A 52-year-old man with no significant past medical history asks
which age-based screening he should prioritize next. He has no
symptoms, a normal physical exam, and no family history of
,cancer. Which screening should you recommend first based on
highest yield for asymptomatic adults in this age group?
A. Low-dose CT scan for lung cancer
B. Colonoscopy (or other guideline-appropriate colorectal
screening)
C. Prostate-specific antigen (PSA) testing
D. Routine brain MRI
Correct Answer
B
Rationales
• Correct (B): Colorectal cancer screening is a high-yield,
age-based preventive priority for adults beginning in mid-
adulthood and remains a core preventive measure for
asymptomatic adults in this age group. CMDT emphasizes
colorectal screening as a primary prevention/screening
priority. accessmedicine.mhmedical.com
• A (incorrect): Low-dose CT is recommended only for
selected adults with a substantial smoking history; it is not
a general screening for all 52-year-olds.
accessmedicine.mhmedical.com
• C (incorrect): PSA testing is individualized and guided by
shared decision-making given harms/benefits; it is not
uniformly first-line for asymptomatic men without risk
factors. accessmedicine.mhmedical.com
, • D (incorrect): Routine brain MRI is not a screening test for
asymptomatic adults and has negligible yield and high
cost/false positives. accessmedicine.mhmedical.com
Teaching Point
Prioritize evidence-based, age-specific screenings (e.g.,
colorectal) for asymptomatic adults.
Citation (Simplified APA)
Papadakis et al. (2025). CURRENT Medical Diagnosis &
Treatment 2026 (65th Ed.). Ch. 1.
2)
Reference
Ch. 1 — Disease Prevention & Health Promotion —
Immunizations & Adult Vaccination.
accessmedicine.mhmedical.com
Question Stem
A 67-year-old woman with well-controlled type 2 diabetes
presents for a routine visit. Which immunization provides the
most immediate, evidence-based reduction in her risk for
severe disease and is recommended for virtually all adults in
this age group?
A. Live attenuated influenza vaccine (LAIV) by intranasal route
B. Herpes zoster recombinant subunit vaccine (Shingrix)
C. BCG (Bacillus Calmette–Guérin) vaccine
D. Routine booster for varicella (chickenpox) vaccine
, Correct Answer
B
Rationales
• Correct (B): Recombinant zoster vaccine is recommended
for older adults (typically ≥50 years) to prevent shingles
and postherpetic neuralgia; CMDT highlights zoster
vaccination as high-value prevention in older adults.
accessmedicine.mhmedical.com
• A (incorrect): Influenza vaccination is recommended
annually; however, LAIV (intranasal) is generally not
preferred for older adults—an inactivated formulation is
standard. accessmedicine.mhmedical.com
• C (incorrect): BCG is not indicated for routine prevention of
disease in US older adults and would not reduce risk of
common vaccine-preventable illnesses in this patient.
accessmedicine.mhmedical.com
• D (incorrect): Most older adults have natural immunity to
varicella; routine booster varicella is not a standard adult
recommendation unless lacking immunity.
accessmedicine.mhmedical.com
Teaching Point
Recombinant zoster vaccine prevents shingles and is strongly
recommended for older adults.
