CURRENT Medical Diagnosis and
Treatment 2026
65th Edition
Author(s)Maxine A. Papadakis; Michael
W. Rabow; Kenneth R. McQuaid; Paul L.
Nadler; Erika Leemann Price
TEST BANK
Part A — Ch. 1 — Disease Prevention & Health Promotion (5
items)
1) Reference
Ch. 1 — Disease Prevention & Health Promotion
,Question Stem
A 52-year-old man with hypertension (on lisinopril) and a 35-
pack-year smoking history asks whether he should start statin
therapy for primary prevention. His 10-year ASCVD risk (pooled
cohort) is 8.6%. Which is the best next step?
Options
A. Start high-intensity statin therapy now.
B. Recommend lifestyle modification and reassess risk in 1 year.
C. Start moderate-intensity statin therapy and counsel on
lifestyle.
D. Defer statin; obtain coronary artery calcium (CAC) score to
refine risk.
Correct Answer
C
Rationales
Correct: Moderate-intensity statin therapy is appropriate for
primary prevention in adults with borderline-to-intermediate
10-year ASCVD risk (≥7.5–20%) when risk-enhancing factors
(e.g., smoking, hypertension) are present; combine with
lifestyle counseling.
A (incorrect): High-intensity statin is generally reserved for very
high risk or established ASCVD rather than this intermediate
primary prevention scenario.
B (incorrect): Waiting without initiating statin undervalues the
presence of risk-enhancing factors; immediate therapy plus
lifestyle is preferred.
,D (incorrect): CAC can refine decision when the clinician and
patient are uncertain, but with an 8.6% risk plus active smoking
and HTN, initiating moderate-intensity statin is reasonable
without delay.
Teaching Point
Use statins for primary prevention when 10-yr ASCVD risk plus
risk enhancers justify therapy.
Citation (Simplified APA)
Papadakis et al. (2025). CURRENT Medical Diagnosis &
Treatment 2026 (65th Ed.). Ch. 1. VitalSource+1
2) Reference
Ch. 1 — Disease Prevention & Health Promotion
Question Stem
A 27-year-old woman is planning pregnancy and asks which
immunizations she should receive before conception. Which is
the most important vaccine to ensure prior to pregnancy?
Options
A. Inactivated influenza vaccine (annual)
B. Live attenuated MMR (measles-mumps-rubella) vaccine if
nonimmune
C. Tetanus-diphtheria-pertussis (Tdap) booster now
D. Human papillomavirus (HPV) vaccine series
Correct Answer
B
, Rationales
Correct: Live MMR is contraindicated during pregnancy and
should be given to nonimmune women before conception to
prevent congenital infection. Ensuring measles immunity prior
to pregnancy is a high-priority preventive step.
A (incorrect): Inactivated influenza vaccine is recommended
during pregnancy (any trimester), but influenza vaccine can be
given during pregnancy — prioritization for preconception
immunization is MMR if nonimmune.
C (incorrect): Tdap is recommended during each pregnancy
(optimally 27–36 weeks), so routine preconception booster is
not the primary pre-pregnancy priority if she is up to date.
D (incorrect): HPV vaccination is important for cancer
prevention, but on the preconception checklist for immediate
pregnancy safety, ensuring MMR immunity is more time-
sensitive.
Teaching Point
Confirm MMR immunity before conception; live vaccines must
be given prior to pregnancy.
Citation (Simplified APA)
Papadakis et al. (2025). CURRENT Medical Diagnosis &
Treatment 2026 (65th Ed.). Ch. 1. VitalSource+1
3) Reference
Ch. 1 — Disease Prevention & Health Promotion
Treatment 2026
65th Edition
Author(s)Maxine A. Papadakis; Michael
W. Rabow; Kenneth R. McQuaid; Paul L.
Nadler; Erika Leemann Price
TEST BANK
Part A — Ch. 1 — Disease Prevention & Health Promotion (5
items)
1) Reference
Ch. 1 — Disease Prevention & Health Promotion
,Question Stem
A 52-year-old man with hypertension (on lisinopril) and a 35-
pack-year smoking history asks whether he should start statin
therapy for primary prevention. His 10-year ASCVD risk (pooled
cohort) is 8.6%. Which is the best next step?
Options
A. Start high-intensity statin therapy now.
B. Recommend lifestyle modification and reassess risk in 1 year.
C. Start moderate-intensity statin therapy and counsel on
lifestyle.
D. Defer statin; obtain coronary artery calcium (CAC) score to
refine risk.
Correct Answer
C
Rationales
Correct: Moderate-intensity statin therapy is appropriate for
primary prevention in adults with borderline-to-intermediate
10-year ASCVD risk (≥7.5–20%) when risk-enhancing factors
(e.g., smoking, hypertension) are present; combine with
lifestyle counseling.
A (incorrect): High-intensity statin is generally reserved for very
high risk or established ASCVD rather than this intermediate
primary prevention scenario.
B (incorrect): Waiting without initiating statin undervalues the
presence of risk-enhancing factors; immediate therapy plus
lifestyle is preferred.
,D (incorrect): CAC can refine decision when the clinician and
patient are uncertain, but with an 8.6% risk plus active smoking
and HTN, initiating moderate-intensity statin is reasonable
without delay.
Teaching Point
Use statins for primary prevention when 10-yr ASCVD risk plus
risk enhancers justify therapy.
Citation (Simplified APA)
Papadakis et al. (2025). CURRENT Medical Diagnosis &
Treatment 2026 (65th Ed.). Ch. 1. VitalSource+1
2) Reference
Ch. 1 — Disease Prevention & Health Promotion
Question Stem
A 27-year-old woman is planning pregnancy and asks which
immunizations she should receive before conception. Which is
the most important vaccine to ensure prior to pregnancy?
Options
A. Inactivated influenza vaccine (annual)
B. Live attenuated MMR (measles-mumps-rubella) vaccine if
nonimmune
C. Tetanus-diphtheria-pertussis (Tdap) booster now
D. Human papillomavirus (HPV) vaccine series
Correct Answer
B
, Rationales
Correct: Live MMR is contraindicated during pregnancy and
should be given to nonimmune women before conception to
prevent congenital infection. Ensuring measles immunity prior
to pregnancy is a high-priority preventive step.
A (incorrect): Inactivated influenza vaccine is recommended
during pregnancy (any trimester), but influenza vaccine can be
given during pregnancy — prioritization for preconception
immunization is MMR if nonimmune.
C (incorrect): Tdap is recommended during each pregnancy
(optimally 27–36 weeks), so routine preconception booster is
not the primary pre-pregnancy priority if she is up to date.
D (incorrect): HPV vaccination is important for cancer
prevention, but on the preconception checklist for immediate
pregnancy safety, ensuring MMR immunity is more time-
sensitive.
Teaching Point
Confirm MMR immunity before conception; live vaccines must
be given prior to pregnancy.
Citation (Simplified APA)
Papadakis et al. (2025). CURRENT Medical Diagnosis &
Treatment 2026 (65th Ed.). Ch. 1. VitalSource+1
3) Reference
Ch. 1 — Disease Prevention & Health Promotion
