1|Page
NR 565 Midterm Exam Review Latest Test
Bank 2025 with 400 Questions and
Correct Verified Answers // NR565 / nr
565 Advanced Pharmacology
Fundamentals
Hepatic microsomal enzyme system or P450 system -
..........ANSWER.......Liver drug metabolism system is called
The movement of drugs from the systemic circulation to the site of
drug action - ..........ANSWER.......drug distribution process
-blood flow to tissues
-ability of drug to exit vascular system
-ability of drug to enter cells - ..........ANSWER.......Three major factors
of drug distribution
Some drugs must enter cells to reach their sites of action
,2|Pa g e
All drugs must enter cells to undergo metabolism and excretion. -
..........ANSWER.......Drug passage across membranes
Lipid solubility
The presence of a transport system or both of these -
..........ANSWER.......Factors that determine the passage of drugs
across all membranes
The movement of a drug from its site of administration into the
systemic circulation. - ..........ANSWER.......Drug absorption process
Rate of absorption determines how soon effects will begin
Amount of absorption helps determine how intense effects will be
Chemical equivalence is if they contain the same amount of the
identical chemical compound (drug)
Bioavailability if the drug they contain is absorbed at the same rate and
to the same extent - ..........ANSWER.......Terms that are associated
with drug absorption
,3|Pa g e
the rate at which the drug dissolves or drug absorption -
..........ANSWER.......rate of dissolution
the larger the surface area, the faster the absorption (small intestine
has a larger surface area than the stomach) -
..........ANSWER.......surface area and absorption
They compete with each other for metabolism and may thereby
decrease the rate at which one or both agents are metabolized (if
metabolism is depressed enough, a drug can accumulate to dangerous
levels) - ..........ANSWER.......Multiple drugs on metabolic pathways
- Accelerated renal excretion of drugs
- Drug inactivation
- Increased therapeutic action
- Activation of "prodrugs"
- Increased toxicity
- Decreased toxicity - ..........ANSWER.......Therapeutic consequences
of drug metabolism
, 4|Page
promotion of renal drug excretion - ..........ANSWER.......The most
important consequence of drug metabolism is?
The ability to elicit only the response for which the drug is given and is
a highly desirable characteristic of a drug - ..........ANSWER.......Drug
selectivity
The fewer side effects it will produce - ..........ANSWER.......The more
selective a drug is...
The regulation of just a few processes - ..........ANSWER.......Each type
of receptor participates in...
Then the effects of the drug will be limited - ..........ANSWER.......If a
drug interacts with only one type of receptor...
NR 565 Midterm Exam Review Latest Test
Bank 2025 with 400 Questions and
Correct Verified Answers // NR565 / nr
565 Advanced Pharmacology
Fundamentals
Hepatic microsomal enzyme system or P450 system -
..........ANSWER.......Liver drug metabolism system is called
The movement of drugs from the systemic circulation to the site of
drug action - ..........ANSWER.......drug distribution process
-blood flow to tissues
-ability of drug to exit vascular system
-ability of drug to enter cells - ..........ANSWER.......Three major factors
of drug distribution
Some drugs must enter cells to reach their sites of action
,2|Pa g e
All drugs must enter cells to undergo metabolism and excretion. -
..........ANSWER.......Drug passage across membranes
Lipid solubility
The presence of a transport system or both of these -
..........ANSWER.......Factors that determine the passage of drugs
across all membranes
The movement of a drug from its site of administration into the
systemic circulation. - ..........ANSWER.......Drug absorption process
Rate of absorption determines how soon effects will begin
Amount of absorption helps determine how intense effects will be
Chemical equivalence is if they contain the same amount of the
identical chemical compound (drug)
Bioavailability if the drug they contain is absorbed at the same rate and
to the same extent - ..........ANSWER.......Terms that are associated
with drug absorption
,3|Pa g e
the rate at which the drug dissolves or drug absorption -
..........ANSWER.......rate of dissolution
the larger the surface area, the faster the absorption (small intestine
has a larger surface area than the stomach) -
..........ANSWER.......surface area and absorption
They compete with each other for metabolism and may thereby
decrease the rate at which one or both agents are metabolized (if
metabolism is depressed enough, a drug can accumulate to dangerous
levels) - ..........ANSWER.......Multiple drugs on metabolic pathways
- Accelerated renal excretion of drugs
- Drug inactivation
- Increased therapeutic action
- Activation of "prodrugs"
- Increased toxicity
- Decreased toxicity - ..........ANSWER.......Therapeutic consequences
of drug metabolism
, 4|Page
promotion of renal drug excretion - ..........ANSWER.......The most
important consequence of drug metabolism is?
The ability to elicit only the response for which the drug is given and is
a highly desirable characteristic of a drug - ..........ANSWER.......Drug
selectivity
The fewer side effects it will produce - ..........ANSWER.......The more
selective a drug is...
The regulation of just a few processes - ..........ANSWER.......Each type
of receptor participates in...
Then the effects of the drug will be limited - ..........ANSWER.......If a
drug interacts with only one type of receptor...
