CURRENT Medical Diagnosis and
Treatment 2026
65th Edition
Author(s)Maxine A. Papadakis; Michael
W. Rabow; Kenneth R. McQuaid; Paul L.
Nadler; Erika Leemann Price
TEST BANK
1
Reference
Ch. 1 — Disease Prevention & Health Promotion —
Immunizations
Question Stem
A 68-year-old woman with well-controlled type 2 diabetes is
seen for an annual visit. She reports no prior zoster vaccination.
,Which of the following is the most appropriate preventive
recommendation based on best-practice guidance for older
adults?
Options
A. Administer live attenuated zoster vaccine today.
B. Administer recombinant zoster vaccine (2-dose series) and
counsel about local/systemic reactions.
C. Defer zoster vaccination because prior varicella infection
confers lifelong protection.
D. Give a single dose of intranasal influenza vaccine instead of
zoster vaccine.
Correct Answer
B
Rationales
Correct: The recombinant zoster vaccine (2-dose series) is
recommended for older adults (≥50–60 years depending on
guideline) including those with chronic conditions such as
diabetes; it is preferred over the live vaccine due to higher
efficacy and safety in older adults.
A: Live attenuated zoster vaccine is generally not preferred in
older adults and is contraindicated in some
immunocompromised patients; the recombinant vaccine has
replaced it in many recommendations.
C: Prior varicella infection does not reliably prevent zoster;
vaccination reduces zoster risk and postherpetic neuralgia.
D: Influenza vaccine prevents influenza but is not a substitute
,for zoster vaccination; intranasal influenza vaccine is not
routinely used in older adults.
Teaching Point
Recombinant zoster vaccine is preferred for older adults to
prevent herpes zoster and complications.
Citation (Simplified APA)
Papadakis et al. (2025). CURRENT Medical Diagnosis &
Treatment 2026 (65th Ed.). Ch. 1. books.google.com+1
2
Reference
Ch. 1 — Disease Prevention & Health Promotion — Cancer
Screening
Question Stem
A 52-year-old man with no symptoms and no family history asks
about colorectal cancer screening. He prefers noninvasive
testing. Which strategy balances effectiveness and safety while
aligning with standard screening recommendations?
Options
A. No screening is needed until age 60 because he is
asymptomatic.
B. Begin screening now with annual fecal immunochemical
testing (FIT) or stool DNA testing per interval recommendations.
C. Colonoscopy only if a single fecal occult blood test is positive;
otherwise defer until age 65.
, D. CT colonography should replace all stool-based testing as
first-line for average-risk adults.
Correct Answer
B
Rationales
Correct: For average-risk adults starting at recommended ages,
noninvasive stool-based tests such as annual FIT (or stool DNA
at recommended intervals) are acceptable alternatives to
colonoscopy when the patient prefers noninvasive options;
positive tests prompt diagnostic colonoscopy.
A: Deferring screening until age 60 would miss guideline-based
initiation ages (typically starting earlier, often at 45–50
depending on guideline).
C: While colonoscopy follows positive stool testing, waiting until
65 without screening misses recommended intervals.
D: CT colonography is an alternative but is not universally
preferred over stool-based testing and requires different
intervals and follow-up for polyps.
Teaching Point
Stool-based tests (FIT, stool DNA) are acceptable noninvasive
colorectal screening options for average-risk adults.
Citation (Simplified APA)
Papadakis et al. (2025). CURRENT Medical Diagnosis &
Treatment 2026 (65th Ed.). Ch. 1. books.google.com+1
Treatment 2026
65th Edition
Author(s)Maxine A. Papadakis; Michael
W. Rabow; Kenneth R. McQuaid; Paul L.
Nadler; Erika Leemann Price
TEST BANK
1
Reference
Ch. 1 — Disease Prevention & Health Promotion —
Immunizations
Question Stem
A 68-year-old woman with well-controlled type 2 diabetes is
seen for an annual visit. She reports no prior zoster vaccination.
,Which of the following is the most appropriate preventive
recommendation based on best-practice guidance for older
adults?
Options
A. Administer live attenuated zoster vaccine today.
B. Administer recombinant zoster vaccine (2-dose series) and
counsel about local/systemic reactions.
C. Defer zoster vaccination because prior varicella infection
confers lifelong protection.
D. Give a single dose of intranasal influenza vaccine instead of
zoster vaccine.
Correct Answer
B
Rationales
Correct: The recombinant zoster vaccine (2-dose series) is
recommended for older adults (≥50–60 years depending on
guideline) including those with chronic conditions such as
diabetes; it is preferred over the live vaccine due to higher
efficacy and safety in older adults.
A: Live attenuated zoster vaccine is generally not preferred in
older adults and is contraindicated in some
immunocompromised patients; the recombinant vaccine has
replaced it in many recommendations.
C: Prior varicella infection does not reliably prevent zoster;
vaccination reduces zoster risk and postherpetic neuralgia.
D: Influenza vaccine prevents influenza but is not a substitute
,for zoster vaccination; intranasal influenza vaccine is not
routinely used in older adults.
Teaching Point
Recombinant zoster vaccine is preferred for older adults to
prevent herpes zoster and complications.
Citation (Simplified APA)
Papadakis et al. (2025). CURRENT Medical Diagnosis &
Treatment 2026 (65th Ed.). Ch. 1. books.google.com+1
2
Reference
Ch. 1 — Disease Prevention & Health Promotion — Cancer
Screening
Question Stem
A 52-year-old man with no symptoms and no family history asks
about colorectal cancer screening. He prefers noninvasive
testing. Which strategy balances effectiveness and safety while
aligning with standard screening recommendations?
Options
A. No screening is needed until age 60 because he is
asymptomatic.
B. Begin screening now with annual fecal immunochemical
testing (FIT) or stool DNA testing per interval recommendations.
C. Colonoscopy only if a single fecal occult blood test is positive;
otherwise defer until age 65.
, D. CT colonography should replace all stool-based testing as
first-line for average-risk adults.
Correct Answer
B
Rationales
Correct: For average-risk adults starting at recommended ages,
noninvasive stool-based tests such as annual FIT (or stool DNA
at recommended intervals) are acceptable alternatives to
colonoscopy when the patient prefers noninvasive options;
positive tests prompt diagnostic colonoscopy.
A: Deferring screening until age 60 would miss guideline-based
initiation ages (typically starting earlier, often at 45–50
depending on guideline).
C: While colonoscopy follows positive stool testing, waiting until
65 without screening misses recommended intervals.
D: CT colonography is an alternative but is not universally
preferred over stool-based testing and requires different
intervals and follow-up for polyps.
Teaching Point
Stool-based tests (FIT, stool DNA) are acceptable noninvasive
colorectal screening options for average-risk adults.
Citation (Simplified APA)
Papadakis et al. (2025). CURRENT Medical Diagnosis &
Treatment 2026 (65th Ed.). Ch. 1. books.google.com+1
