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NUR 654 Midterm – 200+ Verified Q&A | Endocrine, Cancer, Pain Management, Reproductive, Neuro – 2025/2026 | Grand Canyon University

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This document contains over 200 expertly verified questions and answers tailored for the NUR 654 Midterm Exam at Grand Canyon University, aligned with the 2025/2026 academic year. Designed for nurse practitioner students, it covers advanced primary care and specialty topics across adult, reproductive, neurologic, and oncologic domains. The material is structured in high-yield, clinically focused Q&A format, ideal for comprehensive exam preparation and diagnostic reasoning practice. Key topics include: Endocrine disorders: Addison’s disease, Cushing’s syndrome, hyper/hypoparathyroidism, hypercalcemia, hypocalcemia, SIADH Reproductive health: amenorrhea, contraceptive management, PCOS, hormone therapy alternatives, mastitis, BRCA1/2 management, PID, menopause Oncology: palliative care timing, chemo-induced emergencies (e.g., neutropenic fever), tumor lysis syndrome, radiation purposes, cancer pain protocols Neurology & Psychiatry: Bell’s palsy, Parkinson’s, migraines, MS, dementia types (e.g., Lewy body), mental health screening in pediatrics and geriatrics Pediatrics & Psychosocial Care: developmental milestones, behavioral red flags, anorexia nervosa, family stress response, child-parent relational indicators Pharmacology: NSAIDs, opioids, hormone therapies, fluoxetine, contraceptive protocols, side effect profiles, and dosage patterns Each question includes a correct and clear answer, facilitating efficient review for midterm success and clinical application. This study guide is ideal for: FNP and AGNP students at Grand Canyon University Graduate-level nursing students focused on primary care across the lifespan Learners preparing for midterms in advanced practice nursing programs AANP and ANCC exam candidates seeking clinical Q&A review Relevant for courses and tracks such as: NUR 654: Adult & Women’s Health Primary Care Advanced Practice Nursing Midterm Prep Clinical Decision-Making and Diagnostic Evaluation Family and Adult-Gerontology Nurse Practitioner programs Keywords: NUR 654 midterm, endocrine disorders nursing, Cushing’s syndrome, PCOS management, SIADH emergency, cancer pain protocols, contraception guidelines, menopause alternatives, Bell’s palsy treatment, MS vs ALS, BRCA screening, pediatric behavioral flags, advanced pathophysiology, NP midterm review, Grand Canyon University nursing

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NUR 654 Midterm Study Guide 2025/2026
Exam Questions and Verified Answers |
Already Graded A+



A patient has rapid weight gain, amenorrhea without pregnancy, and mild

hypertension. Once confirmatory tests are performed, what is a possible

treatment for this patient? - 🧠 ANSWER ✔✔Pituitary tumor resection


A patient has unexplained weight loss and the provider notes increased

skin pigmentation on light-exposed skin folds along with darkened palmar

creases. Which laboratory tests will the provider order vs NOT order - 🧠

ANSWER ✔✔ORDER: Serum ACTH, Serum electrolytes, TB skin testing


NOT: Serum cortisol

T or F

Patient wishes related to palliative care should be discussed at the initial

visit and updated at preventive visits - 🧠 ANSWER ✔✔T

,T or F

A patient on chemo has a high temperature and absolute neutropenic count

>500,000 needs immediate ER workup - 🧠 ANSWER ✔✔T


Radiation therapy can be used for all of the following in cancer treatment

EXCEPT - 🧠 ANSWER ✔✔Treatment of side effects of chemo


T or F

SIADH is an oncological emergency requiring urgent oncologic care - 🧠

ANSWER ✔✔T


What is an effective pharmacologic medication to treat non-cancer chronic

pain? - 🧠 ANSWER ✔✔Ibuprofen


T or F

The most common sites for breast CA metastasis include lymph, lungs,

liver, bone, and brain - 🧠 ANSWER ✔✔T


What is an FDA approved treatment for osteoporosis? - 🧠 ANSWER

✔✔Biphosphonate therapy


T or F

, Bone density improvement is the primary goal of biphosphonate treatment?

- 🧠 ANSWER ✔✔F (it is to slow the progression of disease)


An elevated serum alkaline phosphate (SAP) may include all of the

following EXCEPT - 🧠 ANSWER ✔✔Hypothyroidism


T or F

Xray findings associated with Paget's disease can show enlargement of

bone and specific deformities (long bone bowing) - 🧠 ANSWER ✔✔T


Symptoms of Cushing's Syndrome include - 🧠 ANSWER ✔✔Amenorrhea


T or F

Pituitary tumor resection may be first line treatment for Cushing's

Syndrome if inidicated - 🧠 ANSWER ✔✔T


Addison's Disease may cause which of the following lab abnormalities? - 🧠

ANSWER ✔✔Elevated ACTH (not hypokalemia, hypernatremia, or

elevated cortisol)

T or F

A patient with suspected hirsituism should be referred to endocrinology for

an evaluation - 🧠 ANSWER ✔✔T

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