,3. The nurse is teaching a patient who will bedischarged home withaprescription foranenteric- coated
a a a a a a a a a a a a a a a a a
a tablet. Which statement by the patient indicates understanding of the teaching?
a a a a a a a a a a
a. Imay crush the tablet and put it inapplesauce to improve absorption.
a a a a a a a a a a a a
b. I should consume acidic foodsto enhance absorption of this medication.
a a a a a a a a a a
c. I should expect a delay in onset of the drugs effects after taking the tablet.
a a a a a a a a a a a a a a
d. Ishould take this medication withhigh-fat foodsto improve its action.
a a a a a a a a a a a
ANS: C
a a
Enteric-coated tablets resist disintegration in the acidic environment of the stomach and disintegrate a a a a a a a a a a a a
when theyreach the small intestine. There is usually some delay in onset of actions after taking these
a a a a a a a a a a a a a a a a a a
a medications. Enteric-coated tablets should not be crushed or chewed, which would alter thetime anda a a a a a a a a a a a a a
locationofabsorption. Acidic foods will not enhance the absorption of the medication. The patient
a a a a a a a a a a a a a a a
a should not to eat high-fat food before ingesting an enteric-coated tablet, because high-fat foods
a a a a a a a a a a a a a
a decrease the absorption rate. a a a
DIF:COGNITIVELEVEL: Applying (Application) REF: dm 3 TOP:
a a a a a a a a
a NURSING PROCESS: Nursing Intervention a a a
MSC:NCLEX:PhysiologicalIntegrity:Pharmacological and ParenteralTherapies
a a a a a a a
4. A patient who is newly diagnosed with type 1 diabetes mellitus asks why insulin must be given
a a a a a a a a a a a a a a a a
bysubcutaneous injection instead of bymouth. The nursewillexplain that this isbecause
a a a a a a a a a a a a a a a
a. absorption is diminished bythe first-pass effects inthe liver. a a a a a a a a a
b. absorption is fasterwhen insulin isgiven subcutaneously. a a a a a a a
c. digestiveenzymes in the gastrointestinaltract prevent absorption. a a a a a a a
d. theoralformis less predictablewith more adverse effects.
a a a a a a a a a
a ANS: C a
Insulin, growth hormones, and other protein-based drugs are destroyed in the small intestine by
a a a a a a a a a a a a a
a digestive enzymes and must be given parenterally. Because insulin is destroyed by digestive
a a a a a a a a a a a a
a enzymes, it would not make it to the liver for metabolism witha first-pass effect.Subcutaneous tissue
a a a a a a a a a a a a a a a a
a has fewer blood vessels, so absorption is slower in such tissue. Insulin is given subcutaneously
a a a a a a a a a a a a a a
a because it is desirable to have it absorb slowly. a a a a a a a a
DIF:COGNITIVELEVEL:Understanding (Comprehension) REF: dm 3 TOP:
a a a a a a a a
a NURSING PROCESS: Nursing Intervention: Patient Teaching a a a a a
MSC:NCLEX:PhysiologicalIntegrity:Pharmacological and ParenteralTherapies
a a a a a a a
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, 5. Thenurse ispreparing to administeranoralmedication that iswater-soluble. The nurse
a a a a a a a a a a a a a
a understands that this drug a a a
a. must be taken on an emptystomach. a a a a a a
b. requires active transport forabsorption. a a a a
c. should be taken with fattyfoods. a a a a a
d. willreadily diffuseinto the gastrointestinal tract.
a a a a a a
a ANS: B a
Water-soluble drugs require a carrier enzyme orprotein to pass throughthe GI membrane. a a a a a a a a a a a a a
DIF:COGNITIVELEVEL:Understanding (Comprehension) REF: dm 4 TOP:
a a a a a a a a
a NURSING PROCESS: Nursing Intervention a a a
MSC:NCLEX:PhysiologicalIntegrity:Pharmacological and ParenteralTherapies
a a a a a a a
6. Anurse is preparing to administeran oraldrugthat isbest absorbed inan acidic environment. How
a a a a a a a a a a a a a a a a a
a will the nurse give the drug?
a a a a a
a. On an emptystomach a a a
b. With a full glass of water a a a a a
c. With food a
d. Withhigh-fatfood a a
a ANS: C a
Food canstimulate theproduction ofgastricacid so medications requiring an acidicenvironment
a a a a a a a a a a a a a
a should be given with a meal. High-fat foods are useful for drugs that are lipid soluble.
a a a a a a a a a a a a a a a
DIF:COGNITIVELEVEL: Applying (Application) REF: dm 4 TOP:
a a a a a a a a
a NURSING PROCESS: Nursing Intervention a a a
MSC:NCLEX:PhysiologicalIntegrity:Pharmacological and ParenteralTherapies
a a a a a a a
7. Thenurse is preparing an injectable drugand wantsto administer it forrapid absorption. How will
a a a a a a a a a a a a a a a a
a the nurse give this medication?
a a a a
a. IMinto thedeltoid muscle
a a a a
b. IM into the glutealmuscle
a a a a
c. SubQ into abdominaltissue a a a
d. SubQintotheupperarm a a a a
a ANS: A a
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