ss s s
aterial
Chapterm1: s s Introduction to
Drugs
, ss s s
aterial
Chapterm1: s s Introduction to
Drugs
Cognitive Level: Application Diffic ss s s ss
ulty: Moderate
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Integrated Process: Nursing process s s s s ss
1.A nurse working in radiology administers iodine to a patient who is having a co
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mputerized axial tomography (CAT) scan. A nurse working on an oncology unit
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administers chemotherapy to patients who have cancer. At the Public Health Dep
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artment, a nurse administers a measles-mumps-rubella (MMR) vaccine to a 14-
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month-
ss
old child as a routine immunization. Which branch of pharmacology best describ
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es the actions of all three nurses?
ss ss ss ss ss ss ss
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
Response:
Pharmacology is the study of the biologic effects of chemicals. Nurses are ss ss ss ss s s ss ss ss s s ss ss
involve d with clinical pharmacology or pharmacotherapeutics, which is a branch
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of pharm acology that deals with the uses of drugs to treat, prevent, and diagnose
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disease. T he nurse working in radiology is administering a drug to help diagnose a
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
disease. T he nurse working on an oncology unit is administering a drug to help
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
treat a diseas
ss ss ss
e. Pharmacoeconomics includes any costs involved in drug therapy.
ss ss ss ss ss ss ss ss
Pharmacodynamics involves how a drug affects the body, and pharmacokinetics
ss ss ss ss ss ss ss ss ss ss
is how the body acts on the drug.
ss ss ss ss ss ss ss ss
Cognitive Level: Comprehension D ss ss ss
ifficulty: Easy
ss s s
Integrated Process: Nursing process s s s s ss
2.A physician has ordered intramuscular injections of morphine, a narcotic, every 4 h
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ours as needed for pain for a motor vehicle accident victim. The nurse is aware that
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there is a high abuse potential for this drug; therefore, morphine is
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categorized as a:
s s s s ss
A) Schedule I drug ss s s
B) Schedule II drug ss s s
C) Schedule III drug s s s s
D) Schedule IV drug ss s s
Ans: B
Response:
Narcotics such as morphine are considered schedule II drugs because of the high a
ss ss ss ss ss ss ss ss ss ss ss ss ss
buse potential with severe dependence liability. Schedule I drugs have high abuse p
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otential and no accepted medical use. Schedule III drugs have a lesser abuse
ss ss s s ss s s ss ss ss ss ss ss ss ss
potent ial than schedule II drugs and an accepted medical use. Schedule IV
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drugs have lo w abuse potential and limited dependence liability.
s s ss ss ss ss ss ss ss ss ss
Cognitive Level: Comprehension ss ss
ssDifficulty: Easy s s
Integrated Process: Communication and documentation s s s s ss s s
3. A nurse working for a drug company is involved in phase III drug evaluation studi
ss ss ss ss ss ss ss ss s s ss ss ss ss ss
, ss s s
aterial
Chapterm1: s s Introduction to
ss es. Which of the followingDrugs
ss ss ss ss might the nurse be responsible for during this stage of
ss ss ss ss ss ss ss ss ss ss
ss drug development?
ss
, ss s s
aterial
Chapterm1: s s Introduction to
Drugs
A) Working with animals who are given experimental drugs ss ss ss ss ss ss ss
B) Monitoring drug effects in patients who are selected to participate in a study, ss ss ss ss ss ss ss ss ss ss ss ss
who have the disease that the drug is meant to treat
ss ss ss ss ss s s ss ss ss s s ss
C) Collecting records of symptoms that participants experience while taking a d ss ss ss ss ss ss ss ss ss ss
rug and determining whether they are caused by the disease or the drug Info
ss ss ss ss ss ss ss ss ss ss ss ss ss ss
D) rming healthy, young volunteer participants of possible risks that could occur
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from taking an experimental drug
ss ss ss ss ss
Ans: C
Response:
Phase III studies involve use of a drug in a vast clinical market where patients are
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
asked to record any symptoms they experience while taking the drugs. Nurses may
ss ss ss ss ss ss ss ss ss ss ss ss ss
be responsible for helping collect and analyze the information to be shared
ss ss ss ss ss s s s s ss ss ss ss ss
with th e Food and Drug Administration (FDA). Use of animals in drug testing
s s ss ss s s s s s s ss ss ss ss ss ss ss ss
is done in the preclinical trials. A select group of patients who are involved in
ss ss ss ss ss ss ss ss ss ss ss ss ss ss s s
phase II studie s participate in studies where the participants have the disease the
ss ss ss ss ss ss ss ss ss ss ss ss ss ss
drug is intended to treat. These patients are monitored closely for drug effects.
ss ss ss s s ss ss ss ss ss s s ss ss ss
Phase I studies invol ve healthy human volunteers who are usually paid for their
ss ss ss ss ss ss ss ss ss ss ss ss ss ss
participation. Nurses m ay observe for adverse effects and toxicity.
ss ss ss ss ss ss ss ss ss ss
Cognitive Level: Comprehension D ss ss ss
ifficulty: Moderate
ss s s
Integrated Process: Nursing Process s s s s ss
4. Which of the following concepts is considered when generic drugs are substituted f
ss ss ss ss ss ss s s ss ss ss ss s s
or brand-name drugs?
ss ss ss
A) Bioavailability
B) Critical concentration ss
C) Distribution
D) Half-life
Ans: A
Response:
Bioavailability is the portion of a dose of a drug that reaches the systemic circulati ss ss ss ss ss ss ss ss ss ss ss ss ss ss
on and is available to act on body cells. Binders used in a generic drug may not be
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
the same as those used in the brand-
ss ss ss ss ss ss ss ss
name drug. Therefore, the way the body breaks down and uses the drug may differ,
ss ss ss ss ss ss ss ss ss s s ss ss ss ss
which may eliminate a substitution. Critical concentration is the amount of a drug
ss ss ss ss ss ss ss ss s s ss ss s s ss
that is needed to cause a therapeutic effect.
ss ss ss s s ss ss ss ss
Distribution is the phase of pharmacokinetics that involves the movement of a drug ss ss ss ss ss ss ss ss ss ss ss ss
to the body's tissues. A drug's half-
ss ss ss ss ss ss ss
life is the time it takes for the amount of drug to decrease to one-
ss ss ss ss ss ss ss ss ss s s ss ss ss ss
half of the peak level.
ss ss ss ss ss
Cognitive Level: Analysis Difficu ss ss ss
sslty: Difficult s s
Integrated Process: Teaching/learning s s s s
A) 5.A nurse is teaching her patient about the use of over-the-
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counter (OTC) drugs. Which of the following statements best informs the patient a
ss ss ss ss ss ss ss ss ss ss ss ss
B) ssbout their safe use? ss ss ss
―OTC drugs are products that are available without prescription for self- ss ss ss ss ss ss ss ss ss ss
treatment of minor complaints.‖ ss ss ss ss
―OTC drugs are considered medications and should be reported on a drug his ss ss ss s s ss s s s s ss s s ss ss ss
Page s s 2
aterial
Chapterm1: s s Introduction to
Drugs
, ss s s
aterial
Chapterm1: s s Introduction to
Drugs
Cognitive Level: Application Diffic ss s s ss
ulty: Moderate
ss s s
Integrated Process: Nursing process s s s s ss
1.A nurse working in radiology administers iodine to a patient who is having a co
ss ss ss ss ss ss ss ss ss ss ss ss ss ss
mputerized axial tomography (CAT) scan. A nurse working on an oncology unit
ss s s ss ss ss ss ss ss ss ss ss ss
administers chemotherapy to patients who have cancer. At the Public Health Dep
ss ss ss ss ss ss ss ss ss ss ss ss
artment, a nurse administers a measles-mumps-rubella (MMR) vaccine to a 14-
ss ss ss ss ss ss ss ss ss ss ss
month-
ss
old child as a routine immunization. Which branch of pharmacology best describ
ss ss ss ss ss ss ss ss ss ss ss
es the actions of all three nurses?
ss ss ss ss ss ss ss
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
Response:
Pharmacology is the study of the biologic effects of chemicals. Nurses are ss ss ss ss s s ss ss ss s s ss ss
involve d with clinical pharmacology or pharmacotherapeutics, which is a branch
ss ss ss ss ss ss ss ss ss ss ss
of pharm acology that deals with the uses of drugs to treat, prevent, and diagnose
ss ss ss ss s s ss ss ss ss s s ss ss ss ss s s
disease. T he nurse working in radiology is administering a drug to help diagnose a
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
disease. T he nurse working on an oncology unit is administering a drug to help
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
treat a diseas
ss ss ss
e. Pharmacoeconomics includes any costs involved in drug therapy.
ss ss ss ss ss ss ss ss
Pharmacodynamics involves how a drug affects the body, and pharmacokinetics
ss ss ss ss ss ss ss ss ss ss
is how the body acts on the drug.
ss ss ss ss ss ss ss ss
Cognitive Level: Comprehension D ss ss ss
ifficulty: Easy
ss s s
Integrated Process: Nursing process s s s s ss
2.A physician has ordered intramuscular injections of morphine, a narcotic, every 4 h
ss ss ss ss ss ss ss ss ss ss ss ss
ours as needed for pain for a motor vehicle accident victim. The nurse is aware that
ss ss ss s s ss ss ss ss ss ss ss ss ss ss ss ss
there is a high abuse potential for this drug; therefore, morphine is
ss ss ss ss s s ss ss ss ss ss s s ss
categorized as a:
s s s s ss
A) Schedule I drug ss s s
B) Schedule II drug ss s s
C) Schedule III drug s s s s
D) Schedule IV drug ss s s
Ans: B
Response:
Narcotics such as morphine are considered schedule II drugs because of the high a
ss ss ss ss ss ss ss ss ss ss ss ss ss
buse potential with severe dependence liability. Schedule I drugs have high abuse p
ss ss ss ss ss ss ss ss ss ss ss ss ss
otential and no accepted medical use. Schedule III drugs have a lesser abuse
ss ss s s ss s s ss ss ss ss ss ss ss ss
potent ial than schedule II drugs and an accepted medical use. Schedule IV
ss ss ss ss ss s s ss s s ss s s ss ss ss
drugs have lo w abuse potential and limited dependence liability.
s s ss ss ss ss ss ss ss ss ss
Cognitive Level: Comprehension ss ss
ssDifficulty: Easy s s
Integrated Process: Communication and documentation s s s s ss s s
3. A nurse working for a drug company is involved in phase III drug evaluation studi
ss ss ss ss ss ss ss ss s s ss ss ss ss ss
, ss s s
aterial
Chapterm1: s s Introduction to
ss es. Which of the followingDrugs
ss ss ss ss might the nurse be responsible for during this stage of
ss ss ss ss ss ss ss ss ss ss
ss drug development?
ss
, ss s s
aterial
Chapterm1: s s Introduction to
Drugs
A) Working with animals who are given experimental drugs ss ss ss ss ss ss ss
B) Monitoring drug effects in patients who are selected to participate in a study, ss ss ss ss ss ss ss ss ss ss ss ss
who have the disease that the drug is meant to treat
ss ss ss ss ss s s ss ss ss s s ss
C) Collecting records of symptoms that participants experience while taking a d ss ss ss ss ss ss ss ss ss ss
rug and determining whether they are caused by the disease or the drug Info
ss ss ss ss ss ss ss ss ss ss ss ss ss ss
D) rming healthy, young volunteer participants of possible risks that could occur
ss ss ss ss ss ss ss ss ss ss ss
from taking an experimental drug
ss ss ss ss ss
Ans: C
Response:
Phase III studies involve use of a drug in a vast clinical market where patients are
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
asked to record any symptoms they experience while taking the drugs. Nurses may
ss ss ss ss ss ss ss ss ss ss ss ss ss
be responsible for helping collect and analyze the information to be shared
ss ss ss ss ss s s s s ss ss ss ss ss
with th e Food and Drug Administration (FDA). Use of animals in drug testing
s s ss ss s s s s s s ss ss ss ss ss ss ss ss
is done in the preclinical trials. A select group of patients who are involved in
ss ss ss ss ss ss ss ss ss ss ss ss ss ss s s
phase II studie s participate in studies where the participants have the disease the
ss ss ss ss ss ss ss ss ss ss ss ss ss ss
drug is intended to treat. These patients are monitored closely for drug effects.
ss ss ss s s ss ss ss ss ss s s ss ss ss
Phase I studies invol ve healthy human volunteers who are usually paid for their
ss ss ss ss ss ss ss ss ss ss ss ss ss ss
participation. Nurses m ay observe for adverse effects and toxicity.
ss ss ss ss ss ss ss ss ss ss
Cognitive Level: Comprehension D ss ss ss
ifficulty: Moderate
ss s s
Integrated Process: Nursing Process s s s s ss
4. Which of the following concepts is considered when generic drugs are substituted f
ss ss ss ss ss ss s s ss ss ss ss s s
or brand-name drugs?
ss ss ss
A) Bioavailability
B) Critical concentration ss
C) Distribution
D) Half-life
Ans: A
Response:
Bioavailability is the portion of a dose of a drug that reaches the systemic circulati ss ss ss ss ss ss ss ss ss ss ss ss ss ss
on and is available to act on body cells. Binders used in a generic drug may not be
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
the same as those used in the brand-
ss ss ss ss ss ss ss ss
name drug. Therefore, the way the body breaks down and uses the drug may differ,
ss ss ss ss ss ss ss ss ss s s ss ss ss ss
which may eliminate a substitution. Critical concentration is the amount of a drug
ss ss ss ss ss ss ss ss s s ss ss s s ss
that is needed to cause a therapeutic effect.
ss ss ss s s ss ss ss ss
Distribution is the phase of pharmacokinetics that involves the movement of a drug ss ss ss ss ss ss ss ss ss ss ss ss
to the body's tissues. A drug's half-
ss ss ss ss ss ss ss
life is the time it takes for the amount of drug to decrease to one-
ss ss ss ss ss ss ss ss ss s s ss ss ss ss
half of the peak level.
ss ss ss ss ss
Cognitive Level: Analysis Difficu ss ss ss
sslty: Difficult s s
Integrated Process: Teaching/learning s s s s
A) 5.A nurse is teaching her patient about the use of over-the-
ss ss ss ss ss ss ss ss ss ss
counter (OTC) drugs. Which of the following statements best informs the patient a
ss ss ss ss ss ss ss ss ss ss ss ss
B) ssbout their safe use? ss ss ss
―OTC drugs are products that are available without prescription for self- ss ss ss ss ss ss ss ss ss ss
treatment of minor complaints.‖ ss ss ss ss
―OTC drugs are considered medications and should be reported on a drug his ss ss ss s s ss s s s s ss s s ss ss ss
Page s s 2
