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Biology Paper 1 Hard Questions Exam with Latest update.docx

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October 30, 2025
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Biology Paper 1 Hard Questions Exam
with Latest update
1) Describe what happens in each stage of the cell cycle.
(4) - CORRECT ANSWERS ✔✔Stage 1:
- DNA/CHROMOSOMES replicate
- cellular structures increase


Stage 2:
- ONE SET of chromosomes are pulled apart to opposite
poles of cell


Stage 3:
- cell membrane AND cytoplasm split


2) a. A survey monitors the risk of developing cirrhosis
amongst ppl who drink alcohol with & without meals.
Suggest one aspect if the survey which may reduce
validity. (1) - CORRECT ANSWERS ✔✔- ppl may
change drinking habits over time
- some may drunk all of their weekly alcohol at once


2) b. Age and gender were 2 factors that were controlled
in this analysis.
Many other factors were also controlled

, Biology Paper 1 Hard Questions Exam
with Latest update
Suggest 3 other factors which the scientists may have
controlled. (2) - CORRECT ANSWERS ✔✔- diet
- BMI
- smoking habits
- medication
- (medical conditions)


2) c. Give an example of a conclusion from the graph;
USE DATA. - CORRECT ANSWERS ✔✔- consuming less
that 50g with meals don't increase the risk
- even 25g a week increase the risk if not with meals


3) Cirrhosis of the liver leads to liver failure
Describe the effects of liver failure on the human body.
(4) - CORRECT ANSWERS ✔✔1) no bile made in liver
- lipids are not emulsified
- S.A of lipids not increased
- pH of small intestine won't be neutralised
- enzymes (in small intestine) will not work effectively or
= may lose weight


2) lactic acid not broken down

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