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Test Bank for Abrams' Clinical Drug Therapy: Rationales for Nursing Practice, 13th Edition by Frandsen & Pennington – Complete Chapters 1–61 with Detailed Rationales | A+ PASS (PDF)

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Ace your pharmacology exams with this extensive 664-page test bank for Abrams' Clinical Drug Therapy: Rationales for Nursing Practice, 13th Edition by Geralyn Frandsen and Sandra Smith Pennington. Spanning all 61 chapters across 10 comprehensive sections, this A+ study resource delivers thousands of expertly crafted multiple-choice questions with in-depth rationales, mirroring the textbook’s focus on safe, evidence-based drug therapy. From foundational concepts in pharmacology quality, safety, and medication administration (Section 1) to lifespan-specific care, hematologic/immunologic disorders, anti-infectives, cardiovascular, respiratory, renal, endocrine, neurologic, and sensory/skin therapies (Sections 2–10), every question strengthens clinical judgment, NCLEX readiness, and nursing process application. Perfect for nursing students and educators seeking chapter-by-chapter mastery of drug classifications, mechanisms, adverse effects, and patient-centered rationales—download instantly in PDF for guaranteed exam success.

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Institution
Pharmacology
Course
Pharmacology

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TEST BANK Complete_
Test Bank for Abrams' Clinical Drug Therapy: Rationales for
Nursing Practice, 13th Edition by Frandsen & Pennington
Complete Chapters 1–61 with Detailed Rationales | A+ PASS
(PDF)

,Chapter 1 : The Foundation of Pharmacology: Quality and Safety
1. A woman diagnosed with obsessive–compulsive disorder has been prescribed oral paroxetine
hydrochloride. What is the expected effect for this prescription?

A. Curative effect on symptoms

B. Systemic effect on symptoms

C. Local effect on symptoms

D. Parenteral effect on symptoms

ANS: B

Rationale: Drugs that produce systemic effects are taken into the body, circulated through the
bloodstream to their sites of action in various body tissues, and eventually eliminated from the body.
Curative agents are given to cure a disease process. In this case, paroxetine hydrochloride will control the
symptoms but not cure the disorder. Drugs with local effects, such as sunscreen and local anesthetics, act




6|Page

,mainly at the site of application. Paroxetine hydrochloride is not administered parenterally. Parenteral
agents are administered subcutaneously, intramuscularly, or intravenously.

PTS: 1 REF: p. 3, Introduction OBJ: 1

NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies TOP:
Chapter: 1: The Foundation of Pharmacology: Quality and Safety

KEY: Integrated Process: Nursing Process

BLM: Cognitive Level: Understand NOT: Multiple Choice



2. A client has been prescribed an antibiotic. This medication is a naturally occurring substance that has
been chemically modified. What is another name for this type of medication?

A. Synthetic drug

B. Semisynthetic drug

C. Biotechnology drug

D. Prototype drug

ANS: B

Rationale: Semisynthetic drugs (e.g., many antibiotics) are naturally occurring substances that have been
chemically modified. Synthetic drugs are more standardized in their chemical characteristics, more
consistent in their effects, and less likely to produce allergic reactions. Biotechnology drugs involve
manipulating DNA and RNA and recombining genes into hybrid molecules that can be inserted into
living organisms. Prototype drugs are the first drug of a particular group to be developed.

PTS: 1 REF: p. 3, Drug Sources OBJ: 1

NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies

TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety KEY: Integrated Process:
Nursing Process

BLM: Cognitive Level: Understand NOT: Multiple Choice



3. Which classification applies to morphine?

A. Central nervous system depressant

B. Central nervous system stimulant

C. Anti-inflammatory

D. Antihypertensive

ANS: A


7|Page

, Rationale: Drugs are classified according to their effects on particular body systems, their therapeutic
uses, and their chemical characteristics. Morphine is classified as a central nervous system depressant and
will produce this effect in the client. A central nervous system stimulant increases attention and raises
mood. An anti-inflammatory agent decreases inflammation at the site of tissue or joint inflammation. An
antihypertensive agent reduces blood pressure.

PTS: 1 REF: p. 3, Drug Classifications and Prototypes OBJ: 1

NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies TOP:
Chapter: 1: The Foundation of Pharmacology: Quality and Safety

KEY: Integrated Process: Nursing Process

BLM: Cognitive Level: Remember NOT: Multiple Choice



4. A client is administered amoxicillin. The generic name of this medication belongs to which drug
group?

A. Selective serotonin reuptake inhibitors

B. Diuretics

C. Penicillins

D. ACE inhibitors

ANS: C

Rationale: The generic name often indicates the drug group (e.g., drugs with generic names ending in
―cillin‖ are penicillins). Selective serotonin reuptake inhibitors are medications that have antidepressant
effects; SSRI is a broad classification, not a generic name. Diuretics are medications that increase urine
output; diuretic is a broad classification, not a generic name. ACE inhibitor is the broad classification for
the angiotensin receptor blockers, not the generic name.

PTS: 1 REF: p. 3, Drug Names OBJ: 2

NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies TOP:
Chapter: 1: The Foundation of Pharmacology: Quality and Safety

KEY: Integrated Process: Nursing Process

BLM: Cognitive Level: Understand NOT: Multiple Choice



5. The administration of diphenhydramine is regulated by which U.S. government agency?

A. Public Health Service

B. Federal Trade Commission

C. Occupational Safety and Health Administration


8|Page

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