Questions All Solved Correct 2025-
2026 Updated.
Describe the experiments that led to the discovery of DNA as the hereditary material - Answer
1. The bacterial transforming principle by Griffith:
found that nonvirulent R-strain takes up a transforming principle from the virulent heat-killed S-
strain. This allowed the R-strain to transform into S-strain becoming virulent.
2. Avery-MacLeod-McCarty Experiment:
S-strain filtrate was made and treated with RNase, DNase, Protease, and Carboase. Those were
then treated with the R-strain and found that the only dample containing both both strains was
the one with Dnase.
3. The Hershey Chase experiment:
Officially concluded that DNA was genetic material from work with phages.
What were the conclusions for the three experiments that led to DNA being the hereditary
meterial? - Answer 1. The bacterial transforming principle by Griffith:
found that nonvirulent R-strain takes up a transforming principle from the virulent heat-killed S-
strain. This allowed the R-strain to transform into S-strain becoming virulent.
2. Avery-MacLeod-McCarty Experiment:
DNA is the transforming factor
3. The Hershey-Chase Experiment:
DNA is the genetic material
What are the building blocks of DNA - Answer nucleotides
What are nucleotides composed of? - Answer 5 carbon sugar, phosphate group, nitrogenous
base
A, T, G, C
Nucleotides combine via___ - Answer covalent bonds
Nucleotides are assembled into polynucleotide chains by:
, Who determined that structure of DNA? - Answer Crick and Watson
Who discovered the secondary structure of proteins using x-ray crystallography? - Answer
Linus Pauling
Does DNA run parallel or anti parallel? - Answer anti-parallel (strand one 5'-3')(strand 2 3'-5')
What is Chargaff's rule? - Answer DNA should have a 1:1 ratio(G=C, A=T)
The haploid human genome is 3 Gbp long (3x10^9 bp). There are approximately 50 trillion cells
in the human body. How long would all of the human genomic DNA in your body be if it were
stretch out end to end? - Answer ~2m
There is approx, 50 trillion cells in the human body. How long would all of the human DNA in
your body be if it were stretched end to end?
a. 10 billion km
b. 100 billion km
c. 1000 billion km - Answer b. 100 billion km
what is the difference in the origins of replication between pro/eukaryotes? - Answer
prokayotes have just one OoR while Eukaryotes have multiple due to their being more complex
than prokaryotes.
what is the expansion around the origin or replication called? - Answer replication bubble
What does DNA polymerase do? - Answer adds nucleotides to the growing DNA chain that are
complementary to the template strand
In prokaryotes there are three DNA pol. Describe what each one does - Answer DNA pol I and
II: repairs
DNA pol III: DNA synthesis
How does replication know where to being? - Answer There are specific nucleotide sequences