RNA 805 Exam 4 Questions AND Correct Answers
A drug with a high hepatic extraction ratio may exhibit a prolonged elimination half-life in an elderly
patient because: - ✔✔Hepatic blood flow diminishes with age
All of the following are potential reasons for delayed recovery from anesthesia in geriatric patients
except: - ✔✔Increased protein binding
All of the following physiologic parameters decrease in the elderly except - ✔✔Closing volume
All of the lung parameters below increase with age except for - ✔✔Total lung capacity
At what age does the MAC value start to decrease? - ✔✔40
Elderly patients have - ✔✔a diminished cardiac response to beta-receptor stimulation
Highly protein-bound drugs display a higher concentration of the free form of the drug in the elderly
population. Why is this? - ✔✔Elderly patients have lower albumin levels
Hypothermia in the elderly is known to increase the risk for (select two) - ✔✔myocardial ischemia
coagulopathy
In a patient who is 65 years of age, you would expect that the mean alveolar concentration for an
inhaled anesthetic would be decreased by about - ✔✔15%
Many central nervous system neurotransmitters decline with age. Which one is most closely associated
with the development of Alzheimer's disease? - ✔✔acetylcholine
Many changes in organ function and composition occur by the eighth decade of life. Match the
appropriate change with the organ system change or diagnostic characteristic with which it is
associated. - ✔✔Serum creatinine concentration - stays the same
Brain mass - decreases
Plasma catecholamine levels - increases
Match the physiologic characteristic with the manner in which it changes with age. - ✔✔Insulin
resistance - increases
CNS activity - decreases
Alpha-1 acid glycoprotein levels - stays the same
Match the respiratory parameter and the change you would expect to occur as a result of increased age.
- ✔✔FEV1 - decreases
Closing volume - increases
A drug with a high hepatic extraction ratio may exhibit a prolonged elimination half-life in an elderly
patient because: - ✔✔Hepatic blood flow diminishes with age
All of the following are potential reasons for delayed recovery from anesthesia in geriatric patients
except: - ✔✔Increased protein binding
All of the following physiologic parameters decrease in the elderly except - ✔✔Closing volume
All of the lung parameters below increase with age except for - ✔✔Total lung capacity
At what age does the MAC value start to decrease? - ✔✔40
Elderly patients have - ✔✔a diminished cardiac response to beta-receptor stimulation
Highly protein-bound drugs display a higher concentration of the free form of the drug in the elderly
population. Why is this? - ✔✔Elderly patients have lower albumin levels
Hypothermia in the elderly is known to increase the risk for (select two) - ✔✔myocardial ischemia
coagulopathy
In a patient who is 65 years of age, you would expect that the mean alveolar concentration for an
inhaled anesthetic would be decreased by about - ✔✔15%
Many central nervous system neurotransmitters decline with age. Which one is most closely associated
with the development of Alzheimer's disease? - ✔✔acetylcholine
Many changes in organ function and composition occur by the eighth decade of life. Match the
appropriate change with the organ system change or diagnostic characteristic with which it is
associated. - ✔✔Serum creatinine concentration - stays the same
Brain mass - decreases
Plasma catecholamine levels - increases
Match the physiologic characteristic with the manner in which it changes with age. - ✔✔Insulin
resistance - increases
CNS activity - decreases
Alpha-1 acid glycoprotein levels - stays the same
Match the respiratory parameter and the change you would expect to occur as a result of increased age.
- ✔✔FEV1 - decreases
Closing volume - increases
