Genetics Exam 2- BIOL 4003 (Brooker)
with complete solutions
Which of the following are 4 criteria the genetic material must fulfill?
A. DNA repair, replication, transmission, variation
B. Store information, replication, transmission, variation
C. Store information, DNA repair, transmission, variation
D. Store information, replication, composed of DNA, variation - correct answer ✔✔ B. Store
information, replication, transmission, variation
Which of the following could be the components of a single nucleotide found within a DNA
strand?
A. ribose, thymine and phosphate
B. deoxyribose, uracil and phosphate
C. deoxyribose, thymine and phosphate
D. deoxyribose, guanine and 3 phosphates - correct answer ✔✔ C. deoxyribose, thymine and
phosphate
You have analyzed the base composition of the genetic material in a virus and found the
following: 32% adenine, 17% thymine, 18% guanine, and 33% cytosine. From this analysis,
which of the following is the most likely structure of the viral genome?
A. single-stranded DNA
B. double-stranded DNA
C. single-stranded RNA
D. double-stranded RNA - correct answer ✔✔ A. single-stranded DNA
,What feature of DNA allows it to store information?
A. the 5' to 3' direction of the strands
B. the base sequence
C. the relative locations of the major and minor groove
D. the spiral structure - correct answer ✔✔ B. the base sequence
In a DNA strand, a phosphate connects a 3' carbon atom in one deoxyribose to
A. a 5' carbon in an adjacent deoxyribose
B. a 3' carbon in an adjacent deoxyribose
C. a base in an adjacent nucleotide
D. none of the above - correct answer ✔✔ A. a 5' carbon in an adjacent deoxyribose
Positive supercoiling can
A. make a segment of DNA more compact
B. enhance the expression of genes
C. enhance the replication of DNA
D. do all of the above - correct answer ✔✔ A. make a segment of DNA more compact
Two circular DNA molecules are topoisomers of each other; they contain the same amount of
DNA. Let's call them DNA-1 and DNA-2. Under the electron microscope, DNA-1 appears more
compact compared to DNA-2. The level of gene transcription is much lower for DNA-2. Which of
the following three possibilities would best explain these observations?
A. DNA-1 has 4 negative supercoils and DNA-2 has 2 positive supercoils
B. DNA-1 has 4 positive supercoils and DNA-2 has 2 negative supercoils
C. DNA-1 has 2 positive supercoils and DNA-2 has 4 negative supercoils
D. DNA-1 has 2 positive supercoils and DNA-2 has 2 negative supercoils - correct answer ✔✔ A.
DNA-1 has 4 negative supercoils and DNA-2 has 2 positive supercoils
, A chromosome territory is a region
A. of a chromosome that carries a cluster of genes
B. of a chromosome that has particular sets of DNA-binding proteins.
C. in a cell nucleus that is occupied by a single chromosome.
D. in a dividing cell where a chromosome will travel via the spindle apparatus. - correct answer
✔✔ C. in a cell nucleus that is occupied by a single chromosome
When a eukaryotic chromosome becomes more compact in preparation for cell division
(changes from euchromatin to heterochromatin), the primary change is that
A. more nucleosomes are formed.
B. the number of base pairs of DNA between nucleosomes becomes shorter.
C. the radial loop domains get much closer together.
D. all of the above - correct answer ✔✔ C. the radial loop domains get much closer together
Which of the following would NOT be a characteristic of a typical eukaryotic chromosome?
A. many genes
B. many origins of replication
C. one telomere
D. one centromere - correct answer ✔✔ C. one telomere
In the experiment of Avery, McLeod, and McCarty, what was the effect when RNase or protease
was added to the DNA extract?
A. It prevented the conversion of type S bacteria into type R bacteria.
B. It allowed the conversion of type S bacteria into type R bacteria.
C. It prevented the conversion of type R bacteria into type S bacteria.
with complete solutions
Which of the following are 4 criteria the genetic material must fulfill?
A. DNA repair, replication, transmission, variation
B. Store information, replication, transmission, variation
C. Store information, DNA repair, transmission, variation
D. Store information, replication, composed of DNA, variation - correct answer ✔✔ B. Store
information, replication, transmission, variation
Which of the following could be the components of a single nucleotide found within a DNA
strand?
A. ribose, thymine and phosphate
B. deoxyribose, uracil and phosphate
C. deoxyribose, thymine and phosphate
D. deoxyribose, guanine and 3 phosphates - correct answer ✔✔ C. deoxyribose, thymine and
phosphate
You have analyzed the base composition of the genetic material in a virus and found the
following: 32% adenine, 17% thymine, 18% guanine, and 33% cytosine. From this analysis,
which of the following is the most likely structure of the viral genome?
A. single-stranded DNA
B. double-stranded DNA
C. single-stranded RNA
D. double-stranded RNA - correct answer ✔✔ A. single-stranded DNA
,What feature of DNA allows it to store information?
A. the 5' to 3' direction of the strands
B. the base sequence
C. the relative locations of the major and minor groove
D. the spiral structure - correct answer ✔✔ B. the base sequence
In a DNA strand, a phosphate connects a 3' carbon atom in one deoxyribose to
A. a 5' carbon in an adjacent deoxyribose
B. a 3' carbon in an adjacent deoxyribose
C. a base in an adjacent nucleotide
D. none of the above - correct answer ✔✔ A. a 5' carbon in an adjacent deoxyribose
Positive supercoiling can
A. make a segment of DNA more compact
B. enhance the expression of genes
C. enhance the replication of DNA
D. do all of the above - correct answer ✔✔ A. make a segment of DNA more compact
Two circular DNA molecules are topoisomers of each other; they contain the same amount of
DNA. Let's call them DNA-1 and DNA-2. Under the electron microscope, DNA-1 appears more
compact compared to DNA-2. The level of gene transcription is much lower for DNA-2. Which of
the following three possibilities would best explain these observations?
A. DNA-1 has 4 negative supercoils and DNA-2 has 2 positive supercoils
B. DNA-1 has 4 positive supercoils and DNA-2 has 2 negative supercoils
C. DNA-1 has 2 positive supercoils and DNA-2 has 4 negative supercoils
D. DNA-1 has 2 positive supercoils and DNA-2 has 2 negative supercoils - correct answer ✔✔ A.
DNA-1 has 4 negative supercoils and DNA-2 has 2 positive supercoils
, A chromosome territory is a region
A. of a chromosome that carries a cluster of genes
B. of a chromosome that has particular sets of DNA-binding proteins.
C. in a cell nucleus that is occupied by a single chromosome.
D. in a dividing cell where a chromosome will travel via the spindle apparatus. - correct answer
✔✔ C. in a cell nucleus that is occupied by a single chromosome
When a eukaryotic chromosome becomes more compact in preparation for cell division
(changes from euchromatin to heterochromatin), the primary change is that
A. more nucleosomes are formed.
B. the number of base pairs of DNA between nucleosomes becomes shorter.
C. the radial loop domains get much closer together.
D. all of the above - correct answer ✔✔ C. the radial loop domains get much closer together
Which of the following would NOT be a characteristic of a typical eukaryotic chromosome?
A. many genes
B. many origins of replication
C. one telomere
D. one centromere - correct answer ✔✔ C. one telomere
In the experiment of Avery, McLeod, and McCarty, what was the effect when RNase or protease
was added to the DNA extract?
A. It prevented the conversion of type S bacteria into type R bacteria.
B. It allowed the conversion of type S bacteria into type R bacteria.
C. It prevented the conversion of type R bacteria into type S bacteria.
