ABPN Neuro Boards Review Exam Questions AND Correct Answers
AD nocturnal frontal lobe epilepsy is associated with a defect in what gene?
What does that gene encode? - ✔✔CHRNA4 gene; alpha-4 subunit of nicotinic
acetylcholine receptor
After conservative measures fail, what is a good pain relief option for
osteoporotic and pathologic compression fractures? - ✔✔Kyphoplasty (inserting
a balloon into the vertebral body for height restoration and then injecting
polymethyl methacrylate (PMMA) cement to stabilize the fracture.
Alzheimer type II astrocytes are enlarged pale astrocytes seen in: - ✔✔Hepatic
encephalopathy and Wilson Disease
Amphetamine toxicity treatment - ✔✔Activated charcoal, benzos, fluids,
supportive care.
ASM toxicity with ataxia, nystagmus, and poor coordination in setting of
nonlinear kinetics - ✔✔Phenytoin toxicity
At least how many CAG repeats for HD to be fully penetrant? - ✔✔40
Ataxic breathing localizes to: - ✔✔Medial medulla
Breathing with an irregular rate and rhythm separated by irregular pauses -
✔✔Ataxic breathing
,Brown-Sequard syndrome - ✔✔1) Ipsilateral weakness below level of lesion
2) Ipsilateral loss of vibration/proprioception below level of lesion
3) Contralateral loss of pain and temperature below level of lesion
Bunina bodies are a pathologic hallmark of what disease? - ✔✔ALS (these are
small eosinophlic inclusions found in motor neurons)
Can you give TNK for arterial dissection? - ✔✔Yes
Can you use SSRIs for all post-stroke depression? - ✔✔No. Be careful after
hemorrhagic strokes as there has been a link of SSRIs to spontaneous ICH.
Characteristics of SMA - ✔✔1) Proximal weakness
2) Preserved facial movements
3) Absent DTRs
4) Tongue fasciculations
5) Contractures
Cheyne-Stokes respirations are caused by lesions where? - ✔✔Bilateral
hemispheres
Cheyne-Stokes respirations description - ✔✔Slow breathing oscillating between
hyperventilation and hypoventilation
, Chorea secondary to stroke has an acute onset and most often localizes to the: -
✔✔Contralateral STN
Cortical blindness can be caused by what lesions? - ✔✔Bilateral occipital lobe
infarctions (lesion in postgeniculate visual pathway)
Difficulty with obsessions and compulsions that cause distress to the patient
and can interfere with functioning. - ✔✔OCD
Dominant inferior parietal lesions can cause: - ✔✔Gerstmann Syndrome
Dorsal midbrain tegmentum lesion, ipsilateral CN III palsy, contralateral
cerebellar ataxia - ✔✔Claude syndrome
Embryonal tumor with multilayered rosettes (ETMR) - ✔✔Non-
medulloblastoma embryonal tumor.
C19MC amplification on chromosome 19.
Encephalopathy, headaches, nausea, vomiting, bitter odor - ✔✔Cyanide toxicity
Episodic ataxia type 2 is characterized by: - ✔✔Ataxia with brainstem symptoms
(nystagmus, vertigo, double vision, and dysarthria).
Genetic abnormality in Fragile X syndrome - ✔✔CGG
AD nocturnal frontal lobe epilepsy is associated with a defect in what gene?
What does that gene encode? - ✔✔CHRNA4 gene; alpha-4 subunit of nicotinic
acetylcholine receptor
After conservative measures fail, what is a good pain relief option for
osteoporotic and pathologic compression fractures? - ✔✔Kyphoplasty (inserting
a balloon into the vertebral body for height restoration and then injecting
polymethyl methacrylate (PMMA) cement to stabilize the fracture.
Alzheimer type II astrocytes are enlarged pale astrocytes seen in: - ✔✔Hepatic
encephalopathy and Wilson Disease
Amphetamine toxicity treatment - ✔✔Activated charcoal, benzos, fluids,
supportive care.
ASM toxicity with ataxia, nystagmus, and poor coordination in setting of
nonlinear kinetics - ✔✔Phenytoin toxicity
At least how many CAG repeats for HD to be fully penetrant? - ✔✔40
Ataxic breathing localizes to: - ✔✔Medial medulla
Breathing with an irregular rate and rhythm separated by irregular pauses -
✔✔Ataxic breathing
,Brown-Sequard syndrome - ✔✔1) Ipsilateral weakness below level of lesion
2) Ipsilateral loss of vibration/proprioception below level of lesion
3) Contralateral loss of pain and temperature below level of lesion
Bunina bodies are a pathologic hallmark of what disease? - ✔✔ALS (these are
small eosinophlic inclusions found in motor neurons)
Can you give TNK for arterial dissection? - ✔✔Yes
Can you use SSRIs for all post-stroke depression? - ✔✔No. Be careful after
hemorrhagic strokes as there has been a link of SSRIs to spontaneous ICH.
Characteristics of SMA - ✔✔1) Proximal weakness
2) Preserved facial movements
3) Absent DTRs
4) Tongue fasciculations
5) Contractures
Cheyne-Stokes respirations are caused by lesions where? - ✔✔Bilateral
hemispheres
Cheyne-Stokes respirations description - ✔✔Slow breathing oscillating between
hyperventilation and hypoventilation
, Chorea secondary to stroke has an acute onset and most often localizes to the: -
✔✔Contralateral STN
Cortical blindness can be caused by what lesions? - ✔✔Bilateral occipital lobe
infarctions (lesion in postgeniculate visual pathway)
Difficulty with obsessions and compulsions that cause distress to the patient
and can interfere with functioning. - ✔✔OCD
Dominant inferior parietal lesions can cause: - ✔✔Gerstmann Syndrome
Dorsal midbrain tegmentum lesion, ipsilateral CN III palsy, contralateral
cerebellar ataxia - ✔✔Claude syndrome
Embryonal tumor with multilayered rosettes (ETMR) - ✔✔Non-
medulloblastoma embryonal tumor.
C19MC amplification on chromosome 19.
Encephalopathy, headaches, nausea, vomiting, bitter odor - ✔✔Cyanide toxicity
Episodic ataxia type 2 is characterized by: - ✔✔Ataxia with brainstem symptoms
(nystagmus, vertigo, double vision, and dysarthria).
Genetic abnormality in Fragile X syndrome - ✔✔CGG
