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ANPS 8005 midterm questions with complete solutions
Pharmacodynamics - ANSWER-How drugs affect our body
A drug with a narrow therapeutic index has - ANSWER-A small window
between therapeutic effects and toxic effects
When interacting with a receptor, an antagonist - ANSWER-Prevents all activity
of the receptor
Which is an example of a medication class that targets neurotransmitter
metabolism - ANSWER-SSRI's
When the medication interacts with a ligand gated ion channel it - ANSWER-
Produces a conformational change adjusting the flow of ions thru the channel
Ultimate goal of neurotransmission - ANSWER-To alter the biochemical
activities of the post synaptic neuron
Retrograde neurotransmission happens when - ANSWER-Activity flows from the
post synaptic neuron to the pre-synaptic neuron- example, cannabinoids
What does epigenetic determine? - ANSWER-Whether or not a gene gets
expressed
, Page 2 of 12
Name the five molecular targets of psychotropic drugs - ANSWER-
neurotransmitter reuptake, G, protein linked, enzymes, ligand gated ion channel,
voltage gated ion channel
Serotonin, Nora epinephrine, dopamine are transporters that carry
neurotransmitters back into the neuron using - ANSWER-A sodium pump which
causes sodium to decrease, allowing neurotransmitters to increase
protein pumps - ANSWER-Uses energy from charging proteins to draw
neurotransmitters in I.e. VMATs (vesicular transporters
G protein linked receptor has three potential actions - ANSWER-Agonist, partial,
agonist, antagonist (silent)
An inverse agonist - ANSWER-Produces conformational change that inactivates
receptor/removes baseline activity (police not allowing anyone to touch)
What happens in neurotransmitter metabolism? - ANSWER-Enzymes convert a
substrate into a product
Name two types of ion channels - ANSWER-Ligand gated and voltage gated
voltage-gated ion channels - ANSWER-Electrical impulse creates channel
ANPS 8005 midterm questions with complete solutions
Pharmacodynamics - ANSWER-How drugs affect our body
A drug with a narrow therapeutic index has - ANSWER-A small window
between therapeutic effects and toxic effects
When interacting with a receptor, an antagonist - ANSWER-Prevents all activity
of the receptor
Which is an example of a medication class that targets neurotransmitter
metabolism - ANSWER-SSRI's
When the medication interacts with a ligand gated ion channel it - ANSWER-
Produces a conformational change adjusting the flow of ions thru the channel
Ultimate goal of neurotransmission - ANSWER-To alter the biochemical
activities of the post synaptic neuron
Retrograde neurotransmission happens when - ANSWER-Activity flows from the
post synaptic neuron to the pre-synaptic neuron- example, cannabinoids
What does epigenetic determine? - ANSWER-Whether or not a gene gets
expressed
, Page 2 of 12
Name the five molecular targets of psychotropic drugs - ANSWER-
neurotransmitter reuptake, G, protein linked, enzymes, ligand gated ion channel,
voltage gated ion channel
Serotonin, Nora epinephrine, dopamine are transporters that carry
neurotransmitters back into the neuron using - ANSWER-A sodium pump which
causes sodium to decrease, allowing neurotransmitters to increase
protein pumps - ANSWER-Uses energy from charging proteins to draw
neurotransmitters in I.e. VMATs (vesicular transporters
G protein linked receptor has three potential actions - ANSWER-Agonist, partial,
agonist, antagonist (silent)
An inverse agonist - ANSWER-Produces conformational change that inactivates
receptor/removes baseline activity (police not allowing anyone to touch)
What happens in neurotransmitter metabolism? - ANSWER-Enzymes convert a
substrate into a product
Name two types of ion channels - ANSWER-Ligand gated and voltage gated
voltage-gated ion channels - ANSWER-Electrical impulse creates channel
