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,ABRAMS' CLINICAL DRUG THERAPY: RATIONALES FOR NURSING PRACTICE
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,ABRAMS' CLINICAL DRUG THERAPY: RATIONALES FOR NURSING PRACTICE
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, ABRAMS' CLINICAL DRUG THERAPY: RATIONALES FOR NURSING PRACTICE
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Chapter 1, The Foundation of Pharmacology: Quality and Safety
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1. A woman diagnosed with obsessive–compulsive disorder has been prescribed oral
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paroxetine hydrochloride. What is the expected effect for this prescription?
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A. Curative effect on symptoms 4c 4c 4c
B. Systemic effect on symptoms 4c 4c 4c
C. Local effect on symptoms 4c 4c 4c
D. Parenteral effect on symptoms 4c 4c 4c
ANS: B 4 c
Rationale: Drugs that produce systemic effects are taken into the body, circulated through
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the bloodstream to their sites of action in various body tissues, and eventually eliminated
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from the body. Curative agents are given to cure a disease process. In this case, paroxetine
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hydrochloride will control the symptoms but not cure the disorder. Drugs with local effects,
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such as sunscreen and local anesthetics, act mainly at the site of application. Paroxetine
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hydrochloride is not administered parenterally. Parenteral agents are administered
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subcutaneously, intramuscularly, or intravenously.
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PTS: 1 REF: p. 3, Introduction OBJ: 1 4c 4c
NAT: 4 c Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
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TOP:
4c Chapter: 1: The Foundation of Pharmacology: Quality and Safety 4c 4c 4c 4c 4c 4c 4c 4c
KEY: 4 c Integrated Process: Nursing Process 4c 4c 4c
BLM: 4 cCognitive Level: Understand NOT: Multiple Choice 4c 4c 4 c 4c
2. A client has been prescribed an antibiotic. This medication is a naturally occurring
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substance that has been cheG
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.C is another name for this type of
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medication?
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A. Synthetic drug 4c
B. Semisynthetic drug 4c
C. Biotechnology drug 4c
D. Prototype drug 4c
ANS: B 4 c
Rationale: Semisynthetic drugs (e.g., many antibiotics) are naturally occurring substances
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that have been chemically modified. Synthetic drugs are more standardized in their chemical
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characteristics, more consistent in their effects, and less likely to produce allergic reactions.
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Biotechnology drugs involve manipulating DNA and RNA and recombining genes into
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hybrid molecules that can be inserted into living organisms. Prototype drugs are the first drug
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of a particular group to be developed.
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PTS: 1 REF: p. 3, Drug Sources OBJ: 1 4c 4c 4c
NAT: 4 c Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
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TOP:
4c Chapter: 1: The Foundation of Pharmacology: Quality and Safety 4c 4c 4c 4c 4c 4c 4c 4c
KEY: 4 c Integrated Process: Nursing Process 4c 4c 4c
BLM: 4 cCognitive Level: Understand NOT: Multiple Choice 4c 4c 4 c 4c
3. Which classification applies to morphine? 4c 4c 4c 4c
A. Central nervous system depressant 4c 4c 4c
B. Central nervous system stimulant 4c 4c 4c
ABRAMS' CLINICAL DRUG THERAPY: RATIONALES FOR NURSING PRACTICE
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