Review Questions - WCPC/CWS
Practice Review Questions already
passed
Partial thickness wounds heal by which process? - correct answer ✔✔ Granulation with
contraction
What is granulation tissue? - correct answer ✔✔ Granulation tissue is new connective tissue
and microscopic blood vessels that form on the surfaces of a wound during the healing process.
Granulation tissue typically grows from the base of a wound and is able to fill wounds of almost
any size.
Primary function of fibroblasts in wound healing? - correct answer ✔✔ Collagen synthesis
What cell produces ECM? - correct answer ✔✔ FIBROBLASTS.
Fibroblasts produce and secrete all components of the ECM, including the structural proteins,
adhesive proteins, and a space-filling ground substance composed of glycosaminoglycans and
proteoglycans
What is ECM? - correct answer ✔✔ Extra cellular matrix
Which of the following statements is true regarding inflam phase of wound healing? - correct
answer ✔✔ primary cells involved are leukocytes
What are leukocytes? Role in wound healing? - correct answer ✔✔ Leukocytes are WBC that
fight infections and get rid of debris. The chemicals that trigger an inflammatory response
attract leukocytes to the site of injury or infection. (types of WBC include
Monocytes.
, Lymphocytes.
Neutrophils.
Basophils.
Eosinophils.)
Which cell is responsible for contraction? - correct answer ✔✔ Myofibroblast
Job of myofibroblast? - correct answer ✔✔ contraction
Job of neutrophils? - correct answer ✔✔ 1st to arrive in response to infection/inflammation
At the site of injury, neutrophils initiate healing via direct effects on angiogenesis and cell
proliferation.
Job of Macrophage? - correct answer ✔✔ In the later phases of wound repair, macrophages
ingest apoptotic neutrophils, producing growth factors to support tissue restoration. In the very
late stages, as the wound resolves, macrophages may guide tissue remodeling by producing
factors to promote capillary regression and collagen remodeling.
Macrophage vs Neutrophil? - correct answer ✔✔ neutrophils are granulocytes which work as
phagocytes only in circulation, whereas macrophages are agranulocytes which work as
phagocytes inside the tissues.
Job of fibroblasts? - correct answer ✔✔ A fibroblast is the most common type of cell found in
connective tissue. Fibroblasts secrete collagen proteins that are used to maintain a structural
framework for many tissues. They also play an important role in healing wounds.
What kind of wound often occurs on tips of toes, over malleoli, often dry, minimal exudate? -
correct answer ✔✔ Arterial insuff
Practice Review Questions already
passed
Partial thickness wounds heal by which process? - correct answer ✔✔ Granulation with
contraction
What is granulation tissue? - correct answer ✔✔ Granulation tissue is new connective tissue
and microscopic blood vessels that form on the surfaces of a wound during the healing process.
Granulation tissue typically grows from the base of a wound and is able to fill wounds of almost
any size.
Primary function of fibroblasts in wound healing? - correct answer ✔✔ Collagen synthesis
What cell produces ECM? - correct answer ✔✔ FIBROBLASTS.
Fibroblasts produce and secrete all components of the ECM, including the structural proteins,
adhesive proteins, and a space-filling ground substance composed of glycosaminoglycans and
proteoglycans
What is ECM? - correct answer ✔✔ Extra cellular matrix
Which of the following statements is true regarding inflam phase of wound healing? - correct
answer ✔✔ primary cells involved are leukocytes
What are leukocytes? Role in wound healing? - correct answer ✔✔ Leukocytes are WBC that
fight infections and get rid of debris. The chemicals that trigger an inflammatory response
attract leukocytes to the site of injury or infection. (types of WBC include
Monocytes.
, Lymphocytes.
Neutrophils.
Basophils.
Eosinophils.)
Which cell is responsible for contraction? - correct answer ✔✔ Myofibroblast
Job of myofibroblast? - correct answer ✔✔ contraction
Job of neutrophils? - correct answer ✔✔ 1st to arrive in response to infection/inflammation
At the site of injury, neutrophils initiate healing via direct effects on angiogenesis and cell
proliferation.
Job of Macrophage? - correct answer ✔✔ In the later phases of wound repair, macrophages
ingest apoptotic neutrophils, producing growth factors to support tissue restoration. In the very
late stages, as the wound resolves, macrophages may guide tissue remodeling by producing
factors to promote capillary regression and collagen remodeling.
Macrophage vs Neutrophil? - correct answer ✔✔ neutrophils are granulocytes which work as
phagocytes only in circulation, whereas macrophages are agranulocytes which work as
phagocytes inside the tissues.
Job of fibroblasts? - correct answer ✔✔ A fibroblast is the most common type of cell found in
connective tissue. Fibroblasts secrete collagen proteins that are used to maintain a structural
framework for many tissues. They also play an important role in healing wounds.
What kind of wound often occurs on tips of toes, over malleoli, often dry, minimal exudate? -
correct answer ✔✔ Arterial insuff
