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NR 565 - advanced pharmacology midterm Chamberlain Exam Questions and Answers 100% Correct 2025

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During what trimester is a pregnant woman most at risk for adverse drug reactions with potential long term consequences? -Correct Answers -1st trimester (fetus most at risk d/t rapid growth) What is BEERS criteria? -Correct Answers -Recommendations of medications inappropriate for elderly (65 and older), prescriber ultimately decides What is the CYP450 (cytochrome P450) -Correct Answers -liver enzyme system where medications are metabolized, can either be inducers or inhibitors and create drug-drug interactions CYP450 inducers -Correct Answers -Speed up metabolism of drugs (drug is cleared faster), drug has lesser effect (decrease blood levels of drug), elevate CYP450 enzymes CYP450 inducers pneumonic -Correct Answers -"Bullshit Crap GPS INDUCES rage" CYP450 inducer drug names -Correct Answers -Barbituates, St John wort, Carbamazepine, rifampin, alcohol, phenytoin, griseofulvin, phenobarbital, sulfonylureas CYP450 inhibitors -Correct Answers -inhibit metabolism, increase blood levels of medications CYP450 pneumonic -Correct Answers -"VISA credit card debt INHIBITS spending on designers like CK to look GQ" CYP450 inhibitors drug names -Correct Answers -Valproate, isoniazid, sulfonamides, amiodarone, chloramphenicol, ketoconazole, grapefruit juice, quinidine Physiological changes during pregnancy that impact pharmacodynamics and pharmacokinetic properties of drugs? -Correct Answers -increase glomerular filtration rate leads to increase durg excretion increase hepatic metabolism decrease tone and motility of bowel increase drug absorption Examples of medications that can be teratogenic -Correct Answers -Antiepileptic drugs, antimicrobials such as tetracyclines and fluoroquinolones, vitamin A in large doses, some anticoagulants, and hormonal medications such as diethylstilbestrol (DES). How is absorption of intramuscular medications different in neonates? -Correct Answers -slow and erratic due to low blood flow in muscles first few days of life Why is absorption of medication in the stomach increased in infancy? -Correct Answers -delayed gastric emptying Some medications that should be avoided in the pediatric patient? -Correct Answers -glucocorticoids, discoloration of developing teeth with tetracyclines, and kernicterus with sulfonamides, levofloxacin (antibiotics) aspirin (Severe intoxication from acute overdose) what should be included in medication administration patient education? -Correct Answers -dosage size and timing route and technique of administration duration of treatment drug storage nature and time course of desired responses nature and time course of adverse responses finish taking antibiotic

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NR 565


NR 565 - advanced pharmacology midterm
Chamberlain Exam Questions and
Answers 100% Correct 2025
During what trimester is a pregnant woman most at risk for adverse drug reactions
with potential long term consequences? -Correct Answers ✔-1st trimester (fetus
most at risk d/t rapid growth)

What is BEERS criteria? -Correct Answers ✔-Recommendations of medications
inappropriate for elderly (65 and older), prescriber ultimately decides

What is the CYP450 (cytochrome P450) -Correct Answers ✔-liver enzyme system
where medications are metabolized, can either be inducers or inhibitors and create
drug-drug interactions

CYP450 inducers -Correct Answers ✔-Speed up metabolism of drugs (drug is
cleared faster), drug has lesser effect (decrease blood levels of drug), elevate
CYP450 enzymes

CYP450 inducers pneumonic -Correct Answers ✔-"Bullshit Crap GPS INDUCES
rage"

CYP450 inducer drug names -Correct Answers ✔-Barbituates, St John wort,
Carbamazepine, rifampin, alcohol, phenytoin, griseofulvin, phenobarbital,
sulfonylureas

CYP450 inhibitors -Correct Answers ✔-inhibit metabolism, increase blood levels
of medications

CYP450 pneumonic -Correct Answers ✔-"VISA credit card debt INHIBITS
spending on designers like CK to look GQ"



NR 565

,NR 565


CYP450 inhibitors drug names -Correct Answers ✔-Valproate, isoniazid,
sulfonamides, amiodarone, chloramphenicol, ketoconazole, grapefruit juice,
quinidine

Physiological changes during pregnancy that impact pharmacodynamics and
pharmacokinetic properties of drugs? -Correct Answers ✔-increase glomerular
filtration rate leads to increase durg excretion
increase hepatic metabolism
decrease tone and motility of bowel
increase drug absorption

Examples of medications that can be teratogenic -Correct Answers ✔-Antiepileptic
drugs, antimicrobials such as tetracyclines and fluoroquinolones, vitamin A in
large doses, some anticoagulants, and hormonal medications such as
diethylstilbestrol (DES).

How is absorption of intramuscular medications different in neonates? -Correct
Answers ✔-slow and erratic due to low blood flow in muscles first few days of life

Why is absorption of medication in the stomach increased in infancy? -Correct
Answers ✔-delayed gastric emptying

Some medications that should be avoided in the pediatric patient? -Correct
Answers ✔-glucocorticoids, discoloration of developing teeth with tetracyclines,
and kernicterus with sulfonamides, levofloxacin (antibiotics)
aspirin (Severe intoxication from acute overdose)

what should be included in medication administration patient education? -Correct
Answers ✔-dosage size and timing
route and technique of administration
duration of treatment
drug storage
nature and time course of desired responses
nature and time course of adverse responses

NR 565

,NR 565


finish taking antibiotic

What are some things that put the elderly patient at higher risk for adverse drug
reactions? -Correct Answers ✔-reduced renal function
polypharmacy (the use of five or more medications daily)
greater severity of illness
presence of comorbidities
use of drugs that have a low therapeutic index (e.g., digoxin)
increased individual variation secondary to altered pharmacokinetics
inadequate supervision of long-term therapy
poor patient adherence

How can healthcare providers decrease likelihood of an elderly patient
experiencing an adverse drug reaction? -Correct Answers ✔-obtaining a thorough
drug history that includes over-the-counter medications
considering pharmacokinetic and pharmacodynamics changes due to age
monitoring the patient's clinical response and plasma drug levels
using the simplest regimen possible
monitoring for drug-drug interactions and iatrogenic illness
periodically reviewing the need for continued drug therapy
encouraging the patient to dispose of old medications
taking steps to promote adherence and to avoid drugs on the Beers list

How can we promote medication adherence with elderly patients? -Correct
Answers ✔-simplifying drug regimens
providing clear and concise verbal and written instructions
using an appropriate dosage form
clearly labeling and dispensing easy-to-open containers
developing daily reminders
monitoring frequently
affordability of drugs
support systems




NR 565

, NR 565


Why do nitrates need to be taken no later than 4 PM? -Correct Answers ✔-Need
nitrate free interval so tolerance doesn't develop

Nine factors that impact outcome of medication? -Correct Answers ✔-Gender and
race
Genetics and pharmacogenomics
Variability in absorption
placebo effect
Tolerance
patho
age
bodyweight

Do you need informed consent for genetic testing? -Correct Answers ✔-yes

What is the purpose of the Genetic Information Non-Discriminatory Act? -Correct
Answers ✔-Protects patients from discrimination by employers and insurance
providers based on genetic information

Difference between practice authority and prescriptive authority? -Correct
Answers ✔-Practice authority refers to the nurse practitioner's ability to practice
without physician oversight, whereas prescriptive authority refers to the nurse
practitioner's authority to prescribe medications independently and without
limitations.

Who regulates prescriptive authority? -Correct Answers ✔-the jurisdiction of a
health professional board. This may be the State Board of Nursing, the State Board
of Medicine, or the State Board of Pharmacy, as determined by each state.

What is scope of practice determined by? -Correct Answers ✔-is determined by
state practice and licensure laws.




NR 565

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