ONCC PRACTICE TESTS (OCN -
TREATMENT MODALITIES) QUESTIONS
AND ANSWERS WITH COMPLETE
SOLUTIONS 100% CORRECT RATED A+
NEWLY UPDATED 2025
Question: A patient demonstrates an adequate understanding of the teaching
provided regarding chemotherapy and myelosuppression by stating:
"Myelosuppression is:"
Correct Answer:
"A potential side effect of many cancer treatments."
Explanation:
Chemotherapy can cause myelosuppression, which refers to the decreased
production of blood cells, resulting in neutropenia (low white blood cells),
anemia (low red blood cells), and thrombocytopenia (low platelets). This
is a common side effect of many cancer treatments, particularly
chemotherapy, which impacts the bone marrow's ability to produce these
cells.
Reference:
Polovich, M., Olsen, M., & LeFebvre, K. (Eds.). (2014). Chemotherapy and
biotherapy guidelines and recommendations for practice (4th ed.).
Pittsburgh, PA: Oncology Nursing Society, p. 171.
Question: Alkylating agents exert their effects by:
Answer Choices:
A. Binding to DNA strands, preventing DNA replication and cell
division.
B. Causing the release of toxic free radicals inside the cell, triggering cell
apoptosis.
,Correct Answer:
A. Binding to DNA strands, preventing DNA replication and cell
division.
Explanation:
Alkylating agents work by binding covalently to the DNA strands, leading
to DNA cross-linking. This prevents DNA replication and cell division,
leading to cell death. Alkylating agents are cell cycle-nonspecific and are
effective in treating many types of cancers.
Reference:
Chemotherapy and Biotherapy Guidelines and Recommendations for
Practice (4th ed.). Oncology Nursing Society.
attaching to CD52 on the surface of B and T cells, resulting in antibody-dependent
lysis.
disrupting folate-dependent metabolic processes essential for cell replication. -
ANSWER✔✔binding to DNA strands, preventing DNA replication and cell
division.
Answer: Alkalyting agents break the DNA helix strand and interfere with DNA
replication.
Reference: Polovich, M., Olsen, M., & LeFebvre, K. (Eds.). (2014). Chemotherapy
and biotherapy guidelines and recommendations for practice (4th ed.). Pittsburgh,
PA: Oncology Nursing Society, p. 27(t).
The nurse preparing to instill intravesical mitomycin should wear which of the
following pieces of personal protective equipment?
A plastic face shield
A pair of shoe covers
, A front-closing laboratory gown
One pair of powdered nitrile gloves -ANSWER✔✔A plastic face shield
Answer: A plastic face shield should be used when splashing of hazardous drugs is
possible. Intravesical administration carries a risk of splashing.
Reference: Polovich, M. (2017). Safe handling of hazardous drugs (3rd ed.).
Pittsburgh, PA: Oncology Nursing Society, p. 27.
Adjuvant therapy for breast cancer is administered:
after primary therapy to increase the chance of long-term, disease-free survival.
before primary therapy to shrink a tumor that is inoperable in its current state.
at any time during therapy to cure the patient and kill cancer cells.
to locally treat cancer with minimal harm to normal cells. -ANSWER✔✔after
primary therapy to increase the chance of long-term, disease-free survival.
Answer: The goal of adjuvant therapy is to target minimal, residual disease for
patients at high risk of developing metastasis.
Reference: Polovich, M., Olsen, M., & LeFebvre, K. (Eds.). (2014). Chemotherapy
and biotherapy guidelines and recommendations for practice (4th ed.). Pittsburgh,
PA: Oncology Nursing Society, p. 5.
Hormone therapy is effective for which two types of cancer?
Breast and prostate
TREATMENT MODALITIES) QUESTIONS
AND ANSWERS WITH COMPLETE
SOLUTIONS 100% CORRECT RATED A+
NEWLY UPDATED 2025
Question: A patient demonstrates an adequate understanding of the teaching
provided regarding chemotherapy and myelosuppression by stating:
"Myelosuppression is:"
Correct Answer:
"A potential side effect of many cancer treatments."
Explanation:
Chemotherapy can cause myelosuppression, which refers to the decreased
production of blood cells, resulting in neutropenia (low white blood cells),
anemia (low red blood cells), and thrombocytopenia (low platelets). This
is a common side effect of many cancer treatments, particularly
chemotherapy, which impacts the bone marrow's ability to produce these
cells.
Reference:
Polovich, M., Olsen, M., & LeFebvre, K. (Eds.). (2014). Chemotherapy and
biotherapy guidelines and recommendations for practice (4th ed.).
Pittsburgh, PA: Oncology Nursing Society, p. 171.
Question: Alkylating agents exert their effects by:
Answer Choices:
A. Binding to DNA strands, preventing DNA replication and cell
division.
B. Causing the release of toxic free radicals inside the cell, triggering cell
apoptosis.
,Correct Answer:
A. Binding to DNA strands, preventing DNA replication and cell
division.
Explanation:
Alkylating agents work by binding covalently to the DNA strands, leading
to DNA cross-linking. This prevents DNA replication and cell division,
leading to cell death. Alkylating agents are cell cycle-nonspecific and are
effective in treating many types of cancers.
Reference:
Chemotherapy and Biotherapy Guidelines and Recommendations for
Practice (4th ed.). Oncology Nursing Society.
attaching to CD52 on the surface of B and T cells, resulting in antibody-dependent
lysis.
disrupting folate-dependent metabolic processes essential for cell replication. -
ANSWER✔✔binding to DNA strands, preventing DNA replication and cell
division.
Answer: Alkalyting agents break the DNA helix strand and interfere with DNA
replication.
Reference: Polovich, M., Olsen, M., & LeFebvre, K. (Eds.). (2014). Chemotherapy
and biotherapy guidelines and recommendations for practice (4th ed.). Pittsburgh,
PA: Oncology Nursing Society, p. 27(t).
The nurse preparing to instill intravesical mitomycin should wear which of the
following pieces of personal protective equipment?
A plastic face shield
A pair of shoe covers
, A front-closing laboratory gown
One pair of powdered nitrile gloves -ANSWER✔✔A plastic face shield
Answer: A plastic face shield should be used when splashing of hazardous drugs is
possible. Intravesical administration carries a risk of splashing.
Reference: Polovich, M. (2017). Safe handling of hazardous drugs (3rd ed.).
Pittsburgh, PA: Oncology Nursing Society, p. 27.
Adjuvant therapy for breast cancer is administered:
after primary therapy to increase the chance of long-term, disease-free survival.
before primary therapy to shrink a tumor that is inoperable in its current state.
at any time during therapy to cure the patient and kill cancer cells.
to locally treat cancer with minimal harm to normal cells. -ANSWER✔✔after
primary therapy to increase the chance of long-term, disease-free survival.
Answer: The goal of adjuvant therapy is to target minimal, residual disease for
patients at high risk of developing metastasis.
Reference: Polovich, M., Olsen, M., & LeFebvre, K. (Eds.). (2014). Chemotherapy
and biotherapy guidelines and recommendations for practice (4th ed.). Pittsburgh,
PA: Oncology Nursing Society, p. 5.
Hormone therapy is effective for which two types of cancer?
Breast and prostate
