Comprehensive i-Human Case Study: Evaluation, Diagnosis, and
Management of an Acute Osteoporotic Vertebral Compression
Fracture in a 66-Year-Old Postmenopausal Female Presenting
with Sudden Lower Back Pain – Week 9 (2025 Edition)
,Chief Complaint
“I have severe lower back pain that started suddenly two days
ago after I bent over.”
Patient Information
Name: Mary Johnson
Age: 66 years
Sex: Female
Ethnicity: Caucasian
Setting: Outpatient Clinic
Date: Week 9 Clinical Evaluation – 2025
History of Present Illness (HPI)
Mary Johnson, a 66-year-old postmenopausal female, presents
with acute onset of mid-lumbar back pain for 2 days. The pain
began after she bent over to lift a light laundry basket. She
describes it as a sharp, stabbing pain localized in the midline of
her lower back, without radiation to the legs. The pain worsens
with standing or walking and is partially relieved by lying down.
She denies any recent trauma, fever, numbness, weakness,
bowel or bladder incontinence. She reports a history of
osteoporosis diagnosed 5 years ago, for which she has been
inconsistently taking calcium and vitamin D. She has not been
on bisphosphonate therapy.
Past Medical History
Osteoporosis (diagnosed 5 years ago)
Hypertension
Hyperlipidemia
, Medications
Lisinopril 10 mg PO daily
Atorvastatin 20 mg PO nightly
Calcium carbonate 500 mg PO twice daily (inconsistent use)
Vitamin D3 1000 IU daily
Allergies
No known drug allergies
Social History
Retired teacher
Non-smoker, drinks 1 glass of wine per week
Sedentary lifestyle
Diet low in dairy
Lives alone
Family History
Mother: Osteoporosis, hip fracture at age 78
Father: Coronary artery disease
Sister: Type 2 diabetes
Review of Systems
General: No weight loss, fever, or fatigue
Musculoskeletal: Severe lumbar pain, worse with movement
Neurological: No numbness or weakness
Genitourinary: No incontinence
Other systems: Unremarkable
Physical Examination
General: Elderly female in mild distress due to pain
Vital Signs: BP 132/80 mmHg, HR 86 bpm, RR 18/min, Temp
98.2°F, SpO₂ 98%
Management of an Acute Osteoporotic Vertebral Compression
Fracture in a 66-Year-Old Postmenopausal Female Presenting
with Sudden Lower Back Pain – Week 9 (2025 Edition)
,Chief Complaint
“I have severe lower back pain that started suddenly two days
ago after I bent over.”
Patient Information
Name: Mary Johnson
Age: 66 years
Sex: Female
Ethnicity: Caucasian
Setting: Outpatient Clinic
Date: Week 9 Clinical Evaluation – 2025
History of Present Illness (HPI)
Mary Johnson, a 66-year-old postmenopausal female, presents
with acute onset of mid-lumbar back pain for 2 days. The pain
began after she bent over to lift a light laundry basket. She
describes it as a sharp, stabbing pain localized in the midline of
her lower back, without radiation to the legs. The pain worsens
with standing or walking and is partially relieved by lying down.
She denies any recent trauma, fever, numbness, weakness,
bowel or bladder incontinence. She reports a history of
osteoporosis diagnosed 5 years ago, for which she has been
inconsistently taking calcium and vitamin D. She has not been
on bisphosphonate therapy.
Past Medical History
Osteoporosis (diagnosed 5 years ago)
Hypertension
Hyperlipidemia
, Medications
Lisinopril 10 mg PO daily
Atorvastatin 20 mg PO nightly
Calcium carbonate 500 mg PO twice daily (inconsistent use)
Vitamin D3 1000 IU daily
Allergies
No known drug allergies
Social History
Retired teacher
Non-smoker, drinks 1 glass of wine per week
Sedentary lifestyle
Diet low in dairy
Lives alone
Family History
Mother: Osteoporosis, hip fracture at age 78
Father: Coronary artery disease
Sister: Type 2 diabetes
Review of Systems
General: No weight loss, fever, or fatigue
Musculoskeletal: Severe lumbar pain, worse with movement
Neurological: No numbness or weakness
Genitourinary: No incontinence
Other systems: Unremarkable
Physical Examination
General: Elderly female in mild distress due to pain
Vital Signs: BP 132/80 mmHg, HR 86 bpm, RR 18/min, Temp
98.2°F, SpO₂ 98%
