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Final NR 508 Questions and Answers (100% Correct Answers) Already Graded A+

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Final NR 508 Questions and Answers (100% Correct Answers) Already Graded A+

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Institution
NR 508
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Uploaded on
October 20, 2025
Number of pages
78
Written in
2025/2026
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1
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Final NR 508 Questions and Answers (100%
Correct Answers) Already Graded A+
Nurse practitioner prescriptive authority is regulated by: [ ANS: ]
The State Board of Nursing for each state

The benefits to the patient of having an Advanced Practice
Registered Nurse (APRN) prescriber include: [ ANS: ] Nurses care
for the patient from a holistic approach and include the patient in
decision making regarding their care.
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Clinical judgment in prescribing includes: [ ANS: ] Consulting
nationally recognized guidelines for disease management

Nurse practitioner practice may thrive under health-care reform
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because of: [ ANS: ] The demonstrated ability of nurse practitioners
to control costs and improve patient outcomes

A patient's nutritional intake and laboratory results reflect
hypoalbuminemia. This is critical to prescribing because: [ ANS: ]
Distribution of drugs to target tissue may be affected.

Drugs that have a significant first-pass effect: [ ANS: ] re rapidly
metabolized by the liver and may have little if any desired action

The route of excretion of a volatile drug will likely be the: [ ANS: ]
Bile and feces

Medroxyprogesterone (Depo Provera) is prescribed
intramuscularly (IM) to create a storage reservoir of the drug.
Storage reservoirs: [ ANS: ] Increase the length of time a drug is
available and active

The NP chooses to give cephalexin every 8 hours based on
knowledge of the drug's: [ ANS: ] Biological half-life

, 2
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Azithromycin dosing requires that the first day's dosage be twice
those of the other 4 days of the prescription. This is considered a
loading dose. A loading dose: [ ANS: ] Rapidly achieves drug
levels in the therapeutic range

The point in time on the drug concentration curve that indicates
the first sign of a therapeutic effect is the: [ ANS: ] Onset of action

Phenytoin requires that a trough level be drawn. Peak and trough
levels are done [ ANS: ] To determine if a drug is in the therapeutic
range

A laboratory result indicates that the peak level for a drug is
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above the minimum toxic concentration. This means that the: [
ANS: ] Concentration will produce an adverse response

Drugs that are receptor agonists may demonstrate what
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property? [ ANS: ] Desensitization or downregulation with
continuous use

Drugs that are receptor antagonists, such as beta blockers, may
cause: [ ANS: ] An exaggerated response if abruptly discontinued

Factors that affect gastric drug absorption include: [ ANS: ] Lipid
solubility of the drug

Drugs administered via IV [ ANS: ] begin distribution into the body
immediately

When a medication is added to a regimen for a synergistic effect,
the combined effect of the drugs is: [ ANS: ] Greater than the sum
of the effects of each drug individually

Which of the following statements about bioavailability is true? [
ANS: ] Bioavailability issues are especially important for drugs with
narrow therapeutic ranges or sustained-release mechanisms.

Which of the following statements about the major distribution
barriers (blood-brain or fetal-placental) is true? [ ANS: ] The blood-

, 3
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brain barrier slows the entry of many drugs into and from brain
cells.

Drugs are metabolized mainly by the liver via phase I or phase II
reactions. The purpose of both of these types of reactions is to: [
ANS: ] Change drug molecules to a form that an excretory organ
can excrete

Once they have been metabolized by the liver, the metabolites
may be:
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-More active than the parent drug

-Less active than the parent drug

-Totally "deactivated" so they are excreted without any effect
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-All of the above [ ANS: ] All of the above

All drugs continue to act in the body until they are changed or
excreted. The ability of the body to excrete drugs via the renal
system would be increased by: [ ANS: ] Unbinding a nonvolatile
drug from plasma proteins

Steady state is: [ ANS: ] When the amount of drug in the body
remains constant

Two different pain medications are given together for pain relief.
The drug—drug interaction is [ ANS: ] Additive

Actions taken to reduce drug—drug interaction problems include
all of the following EXCEPT: [ ANS: ] Prescribing a third drug to
counteract the adverse reaction of the combination

. Phase I oxidative-reductive processes of drug metabolism require
certain nutritional elements. Which of the following would reduce
or inhibit this process?

, 4
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-Protein malnutrition

-Iron-deficiency anemia

-Both 1 and 2

-Neither 1 nor 2 [ ANS: ] Neither 1 nor 2

The time required for the amount of drug in the body to decrease
by 50% is called: [ ANS: ] Half-life

An agonist activates a receptor and stimulates a response. When
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given frequently over time, the body may: [ ANS: ] Downregulate
the numbers of that specific receptor

Drug antagonism is best defined as an effect of a drug that: [ ANS:
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] Is modified by the concurrent administration of another drug

Instructions to a client regarding self-administration of oral enteric-
coated tablets should include which of the following statements? [
ANS: ] "To achieve best effect, take the tablet with at least 8
ounces of fluid."

The major reason for not crushing a sustained-release capsule is
that, if crushed, the coated beads of the drugs could possibly
result in: [ ANS: ] Toxicity

Which of the following substances is the most likely to be absorbed
in the intestines rather than in the stomach? [ ANS: ] Sodium
bicarbonate

Which of the following variables is a factor in drug absorption? [
ANS: ] A rich blood supply to the area of absorption leads to
better absorption.

An advantage of prescribing a sublingual medication is that the
medication is: [ ANS: ] Absorbed rapidly

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