Immunology Exam 1 – Practice Questions and Study Guide for Immunity
and Immune Response
What are two examples of phagocytes? - CORRECT ANSWER-Neutrophils (PMN-polymorpho
nuclear) and Macrophages (MO)
True or false: Monocytes are precursors of macrophages. - CORRECT ANSWER-True.
Monocytes are found in blood but when they move into tissues, they are macrophages.
What cells are important for parasite control, allergy, and inflammation? - CORRECT ANSWER-
1. mast cell (release histamine when activated)
2. eosinophil (similar function as mast cell but arrive at scene later)
3. basophil (uncommon; function unknown)
4. dendritic cell (internalize pathogens & active T-cells & help initiate adaptive immune
response-serving as a bridge)
What are two types of lymphocytes? - CORRECT ANSWER-T cells and B cells.
T or F: Plasma cells are B-cells that actively secrete antibodies. - CORRECT ANSWER-True.
What is the effector function? - CORRECT ANSWER-A job that a cell has once it is activated
Some functions of the immune response include: - CORRECT ANSWER-a. recognition of the
pathogen or antigen
b. develop "effector" function
What are the main differences between innate immunity and adaptive immunity? - CORRECT
ANSWER-Innate immunity: quicker response, use less specific mechanisms to recognize
pathogens, unable to eradicate the pathogen completely, doesn't provide immunity for
reinfection.
Define hematopoiesis. - CORRECT ANSWER-Hematopoiesis is the generation of blood cells.
, T or F: Blood cells and certain tissue cells derive from a common hematopoietic stem cell. -
CORRECT ANSWER-True. It's pluripotent & self-renewing (can make many copies of itself)
Immune cells go through which pathways? - CORRECT ANSWER-Lymphoid and myeloid
pathways.
What are examples of granulocytes? - CORRECT ANSWER-neutrophils, basophils, and
eosinophils. They are polymorphonuclear leukocytes that reside in the blood.
What chemical signals drive the path the cell takes to its final fate? - CORRECT ANSWER-1.
colony stimulating factor (CSF) - GCSF (granulocyte colony stimulating factor) --> drives the
production of neutrophils
2. cytokines
3. growth factors
Blood cell development occurs where in the body? - CORRECT ANSWER-fetal liver or spleen,
and bone marrow (adults only)
What does lymphoid progenitor differentiate into? - CORRECT ANSWER-1. B cells
2. T cells
3. Natural Killer (NK) cells
What does myeloid progenitor differentiate into? - CORRECT ANSWER-1. basophils
2. eosinophils
3. neutrophils
4. mast cells
5. dendritic cells
6. monocytes
What are the primary lymphoid tissues? - CORRECT ANSWER-bone marrow and thymus. Sites
where the lymphocytes/leukocytes develop.
and Immune Response
What are two examples of phagocytes? - CORRECT ANSWER-Neutrophils (PMN-polymorpho
nuclear) and Macrophages (MO)
True or false: Monocytes are precursors of macrophages. - CORRECT ANSWER-True.
Monocytes are found in blood but when they move into tissues, they are macrophages.
What cells are important for parasite control, allergy, and inflammation? - CORRECT ANSWER-
1. mast cell (release histamine when activated)
2. eosinophil (similar function as mast cell but arrive at scene later)
3. basophil (uncommon; function unknown)
4. dendritic cell (internalize pathogens & active T-cells & help initiate adaptive immune
response-serving as a bridge)
What are two types of lymphocytes? - CORRECT ANSWER-T cells and B cells.
T or F: Plasma cells are B-cells that actively secrete antibodies. - CORRECT ANSWER-True.
What is the effector function? - CORRECT ANSWER-A job that a cell has once it is activated
Some functions of the immune response include: - CORRECT ANSWER-a. recognition of the
pathogen or antigen
b. develop "effector" function
What are the main differences between innate immunity and adaptive immunity? - CORRECT
ANSWER-Innate immunity: quicker response, use less specific mechanisms to recognize
pathogens, unable to eradicate the pathogen completely, doesn't provide immunity for
reinfection.
Define hematopoiesis. - CORRECT ANSWER-Hematopoiesis is the generation of blood cells.
, T or F: Blood cells and certain tissue cells derive from a common hematopoietic stem cell. -
CORRECT ANSWER-True. It's pluripotent & self-renewing (can make many copies of itself)
Immune cells go through which pathways? - CORRECT ANSWER-Lymphoid and myeloid
pathways.
What are examples of granulocytes? - CORRECT ANSWER-neutrophils, basophils, and
eosinophils. They are polymorphonuclear leukocytes that reside in the blood.
What chemical signals drive the path the cell takes to its final fate? - CORRECT ANSWER-1.
colony stimulating factor (CSF) - GCSF (granulocyte colony stimulating factor) --> drives the
production of neutrophils
2. cytokines
3. growth factors
Blood cell development occurs where in the body? - CORRECT ANSWER-fetal liver or spleen,
and bone marrow (adults only)
What does lymphoid progenitor differentiate into? - CORRECT ANSWER-1. B cells
2. T cells
3. Natural Killer (NK) cells
What does myeloid progenitor differentiate into? - CORRECT ANSWER-1. basophils
2. eosinophils
3. neutrophils
4. mast cells
5. dendritic cells
6. monocytes
What are the primary lymphoid tissues? - CORRECT ANSWER-bone marrow and thymus. Sites
where the lymphocytes/leukocytes develop.
