CORRECT!!
,By 2020, number of women over 50 - ANSWER 64 million
By 2060, number of women over 50 - ANSWER 90 million
What is the US female life expectancy - ANSWER 81.2 years
How many oocytes in the ovary at 20 weeks pregnancy - ANSWER 6-7 Million
How many oocytes left at birth - ANSWER 1-2 million
How many oocytes left at puberty - ANSWER 300,000-500,000
What is the period of change at menopause - ANSWER Climacteric or perimenopause
What is the term for menopause that occurs before age 45 - ANSWER Early
menopause
What is the term for menopause that occurs after age 54 - ANSWER Late menopause
What is the timeframe within the first 8 years after FMP (and what numerical SWAN
stages correspond?) - ANSWER Early post menopause (+1a, +1b, +1c)
What is the timeframe called after 8 years from FMP (and what numerical SWAN stage
corresponds?) - ANSWER Late post menopause (+2)
What is the time before FMP with cycle variability (and what numerical SWAN stages
correspond?) - ANSWER Menopause transition (-2, -1)
What is the time of 7 or more days persistent difference in cycle length (and what
numerical SWAN stage corresponds?) - ANSWER Early menopause transition (-2)
What is the time with 60 or more days of amenorrhea at least once (and what numerical
SWAN stage corresponds?) - ANSWER Late menopause transition (-1)
What is a retrospective determination of 12 months of amenorrhea - ANSWER Natural
menopause
What is the timeframe from onset of menstrual cycle irregularity to 1 year after final
menopause transition - ANSWER Perimenopause
, How many stages in menopause transition in STRAW - ANSWER 2 (-2 early transition,
-1 late transition)
How many stages in postmenopause in STRAW - ANSWER 4 (+1a, +1b and +1c early
PM, +2 late PM)
Which STRAW stage is menarche in - ANSWER -5 early reproductive
In which STRAW stage are cycles every 21 to 35 days - ANSWER -4 Peak reproductive
What differentiates STRAW stage -3b from -3a - ANSWER -3b cycles normal, FSH wnl,
AMH, AFC, inhibit B low
-3a shorter cycles, variable FSH
What effect do inhibin B and AMH have on follicles - ANSWER They prevent too many
follicles from growing at once, so the follicle pool is not depleted too quickly
What happens to inhibin b and AMH levels during menopause transition - ANSWER
Decreased number of follicles leads to decreased levels of both of these products.
This means more follicular atresia
What is a LOOP event - ANSWER Luteal Out of Phase event
Explains why some perimenopausal women have elevated estrogen levels sometimes.
In early menopause, transition, elevated FSH is adequate to recruit a second follicle.
This results in a follicular phase-like rise in estradiol during the luteal phase
Compared to normal weight women, how do the pre-menopause and post menopause
estradiol levels of obese women compare - ANSWER Lower pre-menopause estradiol
Higher post menopause estradiol
Which ethnic groups have lower estradiol levels, compared to white/black/Hispanic
women - ANSWER Chinese and Japanese women
Where is AMH produced - ANSWER Granulosa cells of antral and preantral follicles
When does AMH peak - ANSWER Around 25 yo
(so before age 25, test is not helpful)
How does birth control affect AMH - ANSWER Lowers it
What is AFC - ANSWER Antral follicle count