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What is hypothyroidism? - Hypothyroidism sleep apnea, and cardiac enlargement (dilation
is a condition in which the thyroid gland doesn't and pericardial effusion)
produce enough thyroid hormone.
What diagnostic tests are useful for
What is cretinism?- Hypothyroidism at birth, hypothyroidism?- *TSH*—increased in
resulting in developmental abnormalities primary hypothyroidism and normal or low in
secondary hypothyroidism
What is myxedema?- Severe *T4, free T4*—low in both primary and secondary
hypothyroidism with deposition of hypothyroidism
mucopolysaccharides in the dermis, leading to a
doughy appearance of the skin What is subclinical hypothyroidism?-
Subclinical hypothyroidism is elevated
What are the causes of hypothyroidism?- serum TSH in patients with absent or minimal
Autoimmune disease (Hashimoto's symptoms of hypothyroidism and normal serum
thyroiditis, postpartum thyroiditis), post levels of free thyroxine (T4). Subclinical thyroid
radioiodine ablation, secondary hypothyroidism dysfunction is relatively common; it occurs in
about 15% of older women and 10% of older
men, particularly in those with underlying
What is primary hypothyroidism?- Primary
Hashimoto thyroiditis.
hypothyroidism is due to disease in the thyroid;
thyroid-stimulating hormone (TSH) is increased.
The most common cause is autoimmune. It Antibodies for Hashimoto's?- Antibodies to
usually results from Hashimoto thyroiditis. thyroid peroxidase (anti-TPO autoantibodies) and
antithyroglobulin antibodies (anti-Tg)
What is secondary hypothyroidism?-
What is the treatment for hypothyroidism?-
Secondary hypothyroidism occurs when
the hypothalamus produces insufficient Levothyroxine is most used, as it does not
thyrotropin-releasing hormone (TRH) or the cause a rapid increase in T3 level, which has
pituitary produces insufficient TSH. Sometimes, associated risks in the elderly and in patients with
deficient TSH secretion due to deficient TRH cardiac disease. The dose is adjusted every 6
secretion is termed tertiary hypothyroidism. weeks until TSH levels are in mid-normal range.
What are the common symptoms of What special instructions should be provided to
hypothyroidism?- patients taking Levothyroxine?-
Development is insidious, Thyroid
and early symptoms are nonspecific edema medication should be taken on an empty
(nonpitting), dry hair, fatigue, hoarse voice, stomach, around the same time each day.
constipation, cold intolerance, decreased Afterward, recommend avoiding eating or
appetite, muscle cramps, stiffness, menorrhagia,drinking for 30-60 minutes. Most patients take
slowing of intellect, and depression thyroid hormone in the morning upon waking.
Breakfast, including any coffee or milk, can be
What are the common signs of hypothyroidism?- eaten 30-60 minutes later.[
Non pitting edema, dry hair, temporal
thinning of brows, hoarse voice, expressionless What is myxedema coma?- Myxedema
face, large tongue, ileus, weight gain, carpal coma is an extreme complication of
tunnel, prolonged relaxation phase of DTRs, hypothyroidism in which patients exhibit multiple
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