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Test 4 Exam Questions With Correct Answers
/ // // // // // //
A //fibrin //network //that //contains //trapped //blood //cells //and //platelets //is //called //a(n)
clot
platelets //have //this //cell //in //it's //lineage //in //common //with //all //other //blood //cells
pleura //potential //hematopoietic //cell //(stem //cell)
1st //cell //that //is //identified //as //distinctly //a //part //of //the //platelet //lineage
megakaryoblast
differentiation //progression //for //platelets
stem //cell //=> //megakaryoblast //=> //megakaryocyte //=fragments //into=> //platelets
platelets //don't //have //a...
nucleus
normal //range //for //platelets
150,000 //- //450,000/mL
platelet //half //life
8-12 //days
Cytoplasm //of //platelets //contain
-contractile //proteins
-ER //and //golgi
-mitochondria
-prostaglandins //and //thromboxin
-fibrin //stabilizing //factor //synthesis
-growth //factors
,purpose //of //the //ER //and //golgi //apparatus //in //platelets
-Ca++ //storage
-enzyme //synthesis //for //platelet //function //and //coagulation //factors
types //of //contractile //proteins //found //in //platelets
actin, //myosin, //thrombosthenin
function //of //PG //and //TxA2
platelet //aggregation //, //platelet //anti-aggregation //and //vasoconstriction
function //of //fibrin //stabilizing //factor
stablizes //fibrin //threads //and //clot
function //of //growth //factors
used //to //repair //damaged //tissue/ //promote //healing //of //tissue
Platelet //Cell //Membrane //contains:
-
glycoprotein //coating //( //prevents //platelets //from //adhering //to //normal //vascular //endothelium)
-phospholipids
-receptors //(allow //for //activation)
Definition //of //hemostasis
prevention //of //blood //loss
hemostasis //is //achieved //by //these //mechanisms //in //this //order
- //vascular //constriction
- //platelet //plug //formation
- //blood //coagulation/clot
- //fibrin //formation //& //repair //of //injured //vessel
- //clot //lysis
mechanisms //for //vascular //constriction //for //hemostasis
reflex //vascular //smooth //muscle //spasm, //pain //-> //SNS //reflex //-
> //(norepinephrine, //epi) //vaso //constriction
platelet //release //of //TxA2 //-> //vasoconstriction
, the //greater //the //trauma //the //greater //the....
vasoconstriction. /
/thus....a //cut //shaving //bleeds //a //lot //but //a //severed //limb....not //as //much //as //you //might //think
platelet /
/activation //is //caused //by //contact //with //this //substance //in //damaged //vascular //endothelium
collagen
First //step //of //platelet //plug //formation
platelets /
/swell /
/and //exude //pseudopods; //psuedopods //are //"false //feet": //projections //from //the //platelets
second //step //in //platelet //plug //formation
actin, //myosin, //and //thrombosthenin //contract //= //release //of //clotting //factors.
third //step //in //platelet //plug //formation
platelets //become //sticky, //aggregate, //and //adhere //to //collagen //and //von //Willebrand //factor //in
//blood //vessel //wall
fourth //step //in //platelet //plug //formation
ADP //and //TxA2 //secretion //activates //other //platelets
fifth //step //in //platelet //plug //formation
expression //of //fibrinogen //receptors
sixth //step //in //platelet //plug //formation
fibrin //threads //form //in //plug //(mesh //like)
is //a //platelet //plug //the //same //as //a //clot?
no. /
/platelet /
/plugs /
/are /
/good /
/for //small //damage //but //blood //coagulation //and //clot //formation //are //for //bigger //damage.
von //Willebrand //factor
Advanced
/ /
Physiology
/ /
Test 4 Exam Questions With Correct Answers
/ // // // // // //
A //fibrin //network //that //contains //trapped //blood //cells //and //platelets //is //called //a(n)
clot
platelets //have //this //cell //in //it's //lineage //in //common //with //all //other //blood //cells
pleura //potential //hematopoietic //cell //(stem //cell)
1st //cell //that //is //identified //as //distinctly //a //part //of //the //platelet //lineage
megakaryoblast
differentiation //progression //for //platelets
stem //cell //=> //megakaryoblast //=> //megakaryocyte //=fragments //into=> //platelets
platelets //don't //have //a...
nucleus
normal //range //for //platelets
150,000 //- //450,000/mL
platelet //half //life
8-12 //days
Cytoplasm //of //platelets //contain
-contractile //proteins
-ER //and //golgi
-mitochondria
-prostaglandins //and //thromboxin
-fibrin //stabilizing //factor //synthesis
-growth //factors
,purpose //of //the //ER //and //golgi //apparatus //in //platelets
-Ca++ //storage
-enzyme //synthesis //for //platelet //function //and //coagulation //factors
types //of //contractile //proteins //found //in //platelets
actin, //myosin, //thrombosthenin
function //of //PG //and //TxA2
platelet //aggregation //, //platelet //anti-aggregation //and //vasoconstriction
function //of //fibrin //stabilizing //factor
stablizes //fibrin //threads //and //clot
function //of //growth //factors
used //to //repair //damaged //tissue/ //promote //healing //of //tissue
Platelet //Cell //Membrane //contains:
-
glycoprotein //coating //( //prevents //platelets //from //adhering //to //normal //vascular //endothelium)
-phospholipids
-receptors //(allow //for //activation)
Definition //of //hemostasis
prevention //of //blood //loss
hemostasis //is //achieved //by //these //mechanisms //in //this //order
- //vascular //constriction
- //platelet //plug //formation
- //blood //coagulation/clot
- //fibrin //formation //& //repair //of //injured //vessel
- //clot //lysis
mechanisms //for //vascular //constriction //for //hemostasis
reflex //vascular //smooth //muscle //spasm, //pain //-> //SNS //reflex //-
> //(norepinephrine, //epi) //vaso //constriction
platelet //release //of //TxA2 //-> //vasoconstriction
, the //greater //the //trauma //the //greater //the....
vasoconstriction. /
/thus....a //cut //shaving //bleeds //a //lot //but //a //severed //limb....not //as //much //as //you //might //think
platelet /
/activation //is //caused //by //contact //with //this //substance //in //damaged //vascular //endothelium
collagen
First //step //of //platelet //plug //formation
platelets /
/swell /
/and //exude //pseudopods; //psuedopods //are //"false //feet": //projections //from //the //platelets
second //step //in //platelet //plug //formation
actin, //myosin, //and //thrombosthenin //contract //= //release //of //clotting //factors.
third //step //in //platelet //plug //formation
platelets //become //sticky, //aggregate, //and //adhere //to //collagen //and //von //Willebrand //factor //in
//blood //vessel //wall
fourth //step //in //platelet //plug //formation
ADP //and //TxA2 //secretion //activates //other //platelets
fifth //step //in //platelet //plug //formation
expression //of //fibrinogen //receptors
sixth //step //in //platelet //plug //formation
fibrin //threads //form //in //plug //(mesh //like)
is //a //platelet //plug //the //same //as //a //clot?
no. /
/platelet /
/plugs /
/are /
/good /
/for //small //damage //but //blood //coagulation //and //clot //formation //are //for //bigger //damage.
von //Willebrand //factor
