Middle /
Tennessee
/ /
School
/ /
of
/ /
Anesthesia
/ /
Advanced
/ /
Physiology
/ /
Exam IV Questions With Correct Answers
/ // // // // //
clots //are //made //of //- //CORRECT //ANSWERS(S)✔✔• //fibrin //networks
• //meshwork //of //fibrin //fibers //entrapping //platelets, //blood //cells, //and //plasma
A/
/fibrin /
/network /
/that /
/contains /
/trapped //red //blood //cells //and //platelets //is //called //a... //- //CORRECT //ANSWERS(S)✔✔clot
platelets /
/have /
/this /
/cell /
/in /
/it's /
/lineage /
/in /
,/common /
/with //all //other //blood //cells //- //CORRECT //ANSWERS(S)✔✔pleura //potential //hematopoietic //cell
//(stem //cell)
1st /
/cell /
/that /
/is /
/identified /
/as //distinctly //a //part //of //the //platelet //lineage //- //CORRECT //ANSWERS(S)✔✔megakaryoblast
differentiation /
/progression /
/for /
/platelets //- /
/CORRECT /
/ANSWERS(S)✔✔stem /
/cell //=> //megakaryoblast //=> //megakaryocyte //= //fragments //into=> //platelets
characteristics /
/of //platelets //(thrombocytes) //- //CORRECT //ANSWERS(S)✔✔• //precursor: //megakaryocyte
• //anuclear //(cannot //replicate; //must //be //constantly //regenerated)
• //normal //circulating //concentration: //150,000 //- //450,000 //micro/L
• //half-life: //8 //- //12 //days
cytoplasm /
/of /
/platelets /
/(thrombocytes) //- /
/CORRECT //ANSWERS(S)✔✔• //contractile //proteins: //actin, //myosin, //thrombosthenin
• //ER //and //golgi //apparatus: //calcium //storage //and //enzyme //synthesis
• //mitochondria: //ADP //and //ATP //synthesis
,• //PGs //and //TXA2 //synthesis
• //fibrin-stabilizing //factor //synthesis //
• //growth //factors- //repair //damaged //tissue
fibrin-
stabilizing //factor //function //- //CORRECT //ANSWERS(S)✔✔stabilizes //fibrin //threads //and //clot
PGs /
/and /
/TXA2 /
/(prostaglandins /
/and /
/*thromboxanes*) /
/role //in //the //cytoplasm //- //CORRECT //ANSWERS(S)✔✔• //platelet //aggregation //
• //platelet //anti-aggregation //
• //*vasoconstriction*
importance /
/of /
/glycoprotein /
/coating /
/in /
/cell /
/membrane //- /
/CORRECT /
/ANSWERS(S)✔✔prevents //platelets //from //adhering //to //normal //vascular //endothelium
cell /
/membrane //of //platelets //(thrombocytes) //- //CORRECT //ANSWERS(S)✔✔• //glycoprotein //coating
• //phospholipids //- //coagulation //cascade //and //receptors //on //surface //of //platelet //
• //receptors //- //allow //for //activation
, define //hemostasis //- //CORRECT //ANSWERS(S)✔✔prevention //of //blood //loss
how //is //hemostasis //achieved? //- //CORRECT //ANSWERS(S)✔✔• //vascular //constriction
• //platelet //plug //formation
• //blood //coagulation/blood //clot
• //fibrin //formation //and //repair //of //injured //vessel //
• //clot //lysis
vascular /
/constriction //- /
/CORRECT /
/ANSWERS(S)✔✔trauma //
→/
/vascular /
/smooth //muscle //spasm //→ //pain //and //SNS //reflexes //→(NE, //EPI) //vasoconstriction //→ //platelets
//→ //*TXA2 //→ //vasoconstriction*
*decrease //blood //loss*
*greater //the //trauma, //greater //the //amount //of //constriction*
ex: //.a /
/cut //from //shaving //bleeds //a //lot //but //a //severed //limb....not //as //much //as //you //might //think
platelet /
/plug /
/formation //- /
/CORRECT /
/ANSWERS(S)✔✔• /
/platelets //contact //*damaged //vascular //endothelium* //and //*collagen* //in //blood //vessel //wall
1. //platelets //swell, //exude //pseudopods //(false //feet)
Tennessee
/ /
School
/ /
of
/ /
Anesthesia
/ /
Advanced
/ /
Physiology
/ /
Exam IV Questions With Correct Answers
/ // // // // //
clots //are //made //of //- //CORRECT //ANSWERS(S)✔✔• //fibrin //networks
• //meshwork //of //fibrin //fibers //entrapping //platelets, //blood //cells, //and //plasma
A/
/fibrin /
/network /
/that /
/contains /
/trapped //red //blood //cells //and //platelets //is //called //a... //- //CORRECT //ANSWERS(S)✔✔clot
platelets /
/have /
/this /
/cell /
/in /
/it's /
/lineage /
/in /
,/common /
/with //all //other //blood //cells //- //CORRECT //ANSWERS(S)✔✔pleura //potential //hematopoietic //cell
//(stem //cell)
1st /
/cell /
/that /
/is /
/identified /
/as //distinctly //a //part //of //the //platelet //lineage //- //CORRECT //ANSWERS(S)✔✔megakaryoblast
differentiation /
/progression /
/for /
/platelets //- /
/CORRECT /
/ANSWERS(S)✔✔stem /
/cell //=> //megakaryoblast //=> //megakaryocyte //= //fragments //into=> //platelets
characteristics /
/of //platelets //(thrombocytes) //- //CORRECT //ANSWERS(S)✔✔• //precursor: //megakaryocyte
• //anuclear //(cannot //replicate; //must //be //constantly //regenerated)
• //normal //circulating //concentration: //150,000 //- //450,000 //micro/L
• //half-life: //8 //- //12 //days
cytoplasm /
/of /
/platelets /
/(thrombocytes) //- /
/CORRECT //ANSWERS(S)✔✔• //contractile //proteins: //actin, //myosin, //thrombosthenin
• //ER //and //golgi //apparatus: //calcium //storage //and //enzyme //synthesis
• //mitochondria: //ADP //and //ATP //synthesis
,• //PGs //and //TXA2 //synthesis
• //fibrin-stabilizing //factor //synthesis //
• //growth //factors- //repair //damaged //tissue
fibrin-
stabilizing //factor //function //- //CORRECT //ANSWERS(S)✔✔stabilizes //fibrin //threads //and //clot
PGs /
/and /
/TXA2 /
/(prostaglandins /
/and /
/*thromboxanes*) /
/role //in //the //cytoplasm //- //CORRECT //ANSWERS(S)✔✔• //platelet //aggregation //
• //platelet //anti-aggregation //
• //*vasoconstriction*
importance /
/of /
/glycoprotein /
/coating /
/in /
/cell /
/membrane //- /
/CORRECT /
/ANSWERS(S)✔✔prevents //platelets //from //adhering //to //normal //vascular //endothelium
cell /
/membrane //of //platelets //(thrombocytes) //- //CORRECT //ANSWERS(S)✔✔• //glycoprotein //coating
• //phospholipids //- //coagulation //cascade //and //receptors //on //surface //of //platelet //
• //receptors //- //allow //for //activation
, define //hemostasis //- //CORRECT //ANSWERS(S)✔✔prevention //of //blood //loss
how //is //hemostasis //achieved? //- //CORRECT //ANSWERS(S)✔✔• //vascular //constriction
• //platelet //plug //formation
• //blood //coagulation/blood //clot
• //fibrin //formation //and //repair //of //injured //vessel //
• //clot //lysis
vascular /
/constriction //- /
/CORRECT /
/ANSWERS(S)✔✔trauma //
→/
/vascular /
/smooth //muscle //spasm //→ //pain //and //SNS //reflexes //→(NE, //EPI) //vasoconstriction //→ //platelets
//→ //*TXA2 //→ //vasoconstriction*
*decrease //blood //loss*
*greater //the //trauma, //greater //the //amount //of //constriction*
ex: //.a /
/cut //from //shaving //bleeds //a //lot //but //a //severed //limb....not //as //much //as //you //might //think
platelet /
/plug /
/formation //- /
/CORRECT /
/ANSWERS(S)✔✔• /
/platelets //contact //*damaged //vascular //endothelium* //and //*collagen* //in //blood //vessel //wall
1. //platelets //swell, //exude //pseudopods //(false //feet)
