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HCR 240 PATHOPHYSIOLOGY MIDTERM REVIEW (MODULES 1 - 3) QUESTIONS WITH CORRECT ANSWERS

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HCR 240 PATHOPHYSIOLOGY MIDTERM REVIEW (MODULES 1 - 3) QUESTIONS WITH CORRECT ANSWERS

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Type II hypersensitivity


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Cytotoxic hypersensitivity. Antibody-mediated destruction of healthy cells.

Ex: Transfusion reaction with incompatible blood donor

,Hyperplasia


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Increase in number of cells




Hemolytic disease of the newborn


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Antigen-antibody reaction between a mother's antibodies and her
newborn infant's RBCs at the time of birth. Maternal antibodies (IgM) are
usually against A, B, or Rh surface antigens on newborn RBCs.

Infants are treated with sunlight or phototherapy to break down excess
bilirubin.




Interleukins


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Proteins (cytokines) that stimulate the growth of B and T lymphocytes




TNF-alpha


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, Inflammatory cytokine secreted by macrophages

Induces fever, loss of appetite, and lethargy




Neisseria meningitidis


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aka meningococcus

A gram-negative bacteria that is a common cause of bacterial meningitis.


Can cause outbreaks in people living in close quarters (ex: prisons, dorms,
etc)

Vaccine is available.




Heparin


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Anticoagulant that works by activating antithrombin (AT), the body's natural
clot-dissolving substance


Produced endogenously by mast cells and basophils, or can be
administered intravenously.




Mast cells


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, Granulocyte that releases large amounts of histamine


Similar to basophils, but not found in blood




Mycoplasma pneumoniae


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"Walking pneumonia"




Gangrene


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Condition when prolonged ischemia causes tissue necrosis followed by
bacterial infection




Kernig's sign


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A diagnostic sign for meningitis marked by the person's
inability to extend the leg completely when the thigh is
flexed upon the abdomen and the person is sitting or lying
down

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