m m m m m
Koeppen
Berne and Levy Physiology 7th Edition KoeppenTest Bank
m m m m m m m
, Berne and Levy Physiology 7th Edition
m m m m m
Koeppen: Berne and Levy Physiology, 7th Edition
Koeppen
m m m m m m m
Chapter 01: Principles of Cell m m m m
FunctionTest Bank
m m
Multiple Choice m
1. The subcellular structure that degrades proteins is called the:
m m m m m m m m
A. Tight junction m
B. Mitochondria
C. Lysosome
D. Plasma membrane m
E. Ribosome
ANS: C m
2. An experiment is done to measure the uptake of an amino acid into a cell. The
m m m m m m m m m m m m m m m
following data are obtained:
m m m m
N
If Na+ is removed from the extracellular bathing solution, or if a drug is added that prevents
m m m m m m m m m m m m m m m m
mthe cell from making adenosine triphosphate (ATP), the uptake of amino acid into the cell
m m m m m m m m m m m m m m
mis markedly reduced. According to this information, which of the followingmechanisms is
m m m m m m m m m m m
mprobably responsible for the transport of the amino acid into the cell?
m m m m m m m m m m m
A. Passive diffusion through the lipid bilayer
m m m m m
B. Uniporter
C. Transport ATPase m
D. Na+ symporter m
E. Na+ antiporter
m
ANS: D
m m
3. A membrane permeable by only Na+ separates two compartments
m m m m m m m m
containing Na2SO4,shown as follows:
m m m m
,Berne and Levy Physiology 7th Edition
m m m m m
Koeppen
Electrodes are placed in both compartments, and a voltage is applied (that of compartment
m m m m m m m m m m m m m
A is held at 0 mV). What voltage applied to compartment B would resultin no net
m m m m m m m m m m m m m m m m
movement of Na+ across the membrane separating the compartments?
m m m m m m m m m
–60 mV
A. m
–30 mV
B. m
C.
0 mV m
D. +30 mV m
E. +60 mV m
ANS: E
m m
4. The resting membrane potentN ial oRf a Ic e l lGis –B
85.m
CV. The intracellular and
extracellular concentrations of U S N ions are indicated
m m m m m m mm m m m m
m several m in the following table, as is
m m
m m
m m m m m m m m m
the calculated
m m
Nernst equilibrium potential (Ei) for each of these ions:
m m m m m m m m
Ion Concentration Concentration Ei
Inside Cell m Outside Cell m
Na+ 12 mEq/Lm 145 mEq/L m 66 mV m
K+ 150 mEq/L m 4 mEq/L m –96 mV m
Cl– 30 mEq/Lm 105 mEq/L m –33 mV m
Ca++ 0.0001 mmol/dL m 1 mmol/dL
m 122 mV m
The membrane has channels for Na+, K+, Cl–, and Ca++. The conductance of the
m m m m m m m m m m m m m
membrane is the greatest for which ion?
m m m m m m m
A. Na+
B. K+
C. Cl–
D. Ca++
ANS:
m
Bm
5. A cell contains the following membrane transporters:
m m m m m m
Na+ channelK+ channel
m m
Na+,K+-ATPase
m
The resting membrane voltage of the cell is –80 mV, and the intracellular and
m m m m m m m m m m m m m
, Berne and Levy Physiology 7th Edition
m m m m m
extracellular
Koeppen ion concentrations are as follows:
m m m m m
Ion Intracellular Extracellular
Concentration Concentration
Na+ 10 mEq/L
m 145 mEq/L m
K+ 120 mEq/L
m 4 mEq/L m
The cell is treated with a drug to inhibit the Na+,K+-ATPase. What would be the effect ofthis drug
m m m m m m m m m m m m m m m m m
on the following parameters?
m m m m
Intracellular [Na+] m Intracellular [K+] m Cell Volume
m Membrane Voltage
m
A. Decrease Decrease Decrease Depolarize
B. Increase Decrease Increase Depolarize
C. Increase Increase Increase No change
m
D. Decrease Increase Decrease Hyperpolarize
E. Increase Increase Decrease Hyperpolarize
ANS: B m
6. Which of the labeled proteins (shaded) is attached to the membrane by
m m m m m m m m m m m
a glycosylphosphatidylinositol (GPI) anchor?
m m m m
ANS: E m
7. A cell has channels for Na+, K+, and Cl– in its plasma membrane. The resting
m m m m m m m m
m
m m m m m
membrane potential is –60 mV (cell interior negative). The intracellular and
m m m m m m m m m m m
extracellular concentrations for these ions, as well as the calculated Nernst
m m m m m m m m m m m
potentials, are listed as follows:
m m m m m