Signs - Answers Measurable or objective manifestations
Symptoms - Answers Feelings that the patient describes- subjective manifestations
Iatrogenic - Answers Disease caused by physician or treatment
Nosocomial infections - Answers Infections contracted in the acute care facility
Community-acquired infections - Answers Infections contracted in a public setting outside of
the acute care facility
Idiopathic - Answers Underlying cause is unknown
Inflammation - Answers The initial response of body tissues to local injury
Events that occur in inflammatory response - Answers 1. Alterations in blood flow and vascular
permeability
2. Migration of circulating white blood cells to the interstitium of the injured tissue
3. Phagocytosis and enzymatic digestion of dead cells and tissue elements
4. Repair of injury by regeneration of normal parenchymal cells or proliferation of granulation
tissue and eventual scar formation
Five clinical signs of acute inflammation - Answers Rubor (redness), calor (heat), tumor
(swelling), dolor (pain), and loss of function
Granuloma - Answers A localized area of chronic inflammation, often with central necrosis
Permeable membrane - Answers Allows fluid/cells to pass from one tissue to another tissue or
location
Granulation tissue - Answers Fibrous scar replaces destroyed tissue
Pyogenic bacteria - Answers Thick, yellow fluid called pus (dead white cells)
Abscess - Answers Localized, usually encapsulated, collection of fluid
Bacteremia - Answers Potential involvement of other organs and tissues in the body by
organisms invading the blood vessels
Edema - Answers Accumulation of abnormal amounts of fluid in the intercellular tissue spaces
or body cavities
Anasarca - Answers Generalized edema that occurs with pronounced swelling of subcutaneous
tissues throughout the body
, Elephantiasis - Answers Localized lymphatic obstruction resulting in localized edema
Ischemia - Answers Interference of blood supply to an organ; deprives cells and tissues of
oxygen and nutrients
Infarct - Answers Localized area of ischemic necrosis; produced by occlusion of either arterial
supply or venous drainage
Hemorrhage - Answers Implies rupture of a blood vessel
Hematoma - Answers Accumulation of blood trapped within body tissues
Atrophy - Answers Reduction in the size or number of cells in an organ or tissue, with a
corresponding decrease in function
Hypertrophy - Answers Increase in the size of the cells of a tissue or organ in response to a
demand for increased function
Hyperplasia - Answers Increase in the number of cells in a tissue or organ
Dysplasia - Answers Loss of uniformity of individual cells and their architectural orientation
Neoplasia - Answers Ungoverned abnormal proliferation of cells
Oncology - Answers Study of neoplasms (tumors)
Benign - Answers Growth that closely resembles the cells of origin in structure and function
Malignant - Answers Neoplastic growth that invades and destroys adjacent structures
Metastasize - Answers Malignant neoplasms that travel to distant sites
Carcinoma - Answers Malignant neoplasm of epithelial cell origin
Anaplastic - Answers Undifferentiated cell growth- without form
Sarcoma - Answers Highly malignant tumor originating from connective tissue
Lymphatic spread - Answers Major route by which carcinoma metastasizes
Hematogenous spread - Answers Malignant tumors that have invaded the circulatory system
and travel as neoplastic emboli
Grading - Answers Assessment of aggressiveness or degree of malignancy
Staging - Answers (1) extensiveness of tumor at the primary site
(2) presence or absence of metastases to lymph nodes and distant organs