NURS 6630 MIDTERM Exam (3
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MIDTERM Exam
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• Question 1
The serotonin system is involved in many processes in psychiatry, including, most
prominently, mood, sleep, and psychosis. Of the following neurons listed, from where is
serotonin synthesized?
Response under serotonin subheading and figure 1-18
Feedback: on page 16:
Locus Coeruleus: Norepinephrine
Nucleus basalis: cholinergic neurons
Substantia Nigra: dopamine Ventral
Tegmental area: dopamine
• Question 2
Glia cells play a supportive role in the neuron. A few of the functions of the glial cells
include providing nutrition, maintaining homeostasis, stabilizing synapses, and
myelinating axons. The glial cells are categorized as microglia or macroglia. Of the
macroglia cells, which one plays a role in myelinating axons, which may contribute to
mood disorders if altered?
• Question 3
Which of the following statements below is NOT considered an appropriate treatment
strategy for treatment-resistant depression?
Response “Combination of an SSRI OR an SNRI with a norepinephrine-dopamine
Feedback: re-uptake inhibitor (bupropion) or a serotonin-norepinephrine
antagonist (mirtazapine or mianserin) is a commonly used combination”
• Question 4
What is the strongest established risk factor for bipolar disorder?
Response Feedback:
, MIDTERM EXAM
• Question 5 “The strongest established risk factor for BPD is a family
history of BPD.”
Choose the appropriate pair regarding acetylcholine receptors.
Response “There are two classes of ACh receptors: muscarinic and nicotinic. While
Feedback: muscarinic receptors are G-protein-coupled, nicotinic receptors are ion
channels, which allows for rapid influx of NA+ and Ca2+ into the post-
synaptic neuron.”
• Question 6
An 81-year-old male comes to your clinic today complaining of dry mouth, blurred vision,
and constipation. He has a past medical history significant for hypertension, heart failure,
and depression. Of the following medications, which one is likely contributing to these
side effects?
Response Only TCA is listed with most anticholinergic effects; Page 39 for TCA