WALDEN UNIVERSITY NRNP 6635 FINAL
EXAM 2025/2026 – VERIFIED QUESTIONS AND
ANSWERS
|| 100% GUARANTEED PASS
<UPDATED VERSION>
Neurobiology and Foundations of Psychopharmacology
1. The primary therapeutic effect of SSRIs is achieved through:
A. Blocking dopamine D2 receptors
B. Inhibiting the reuptake of serotonin in the synaptic cleft
C. Antagonizing NMDA glutamate receptors
D. Enhancing GABAergic inhibition
2. Which neurotransmitter system is most directly implicated in the
positive symptoms of schizophrenia?
,A. Serotonin (5-HT)
B. Norepinephrine (NE)
C. Dopamine (DA)
D. Acetylcholine (ACh)
3. The therapeutic lag often seen when initiating an SSRI is most
likely due to:
A. Immediate downregulation of post-synaptic receptors
B. The time required for downregulation of pre-synaptic autoreceptors
and subsequent increased serotonin release
C. Slow absorption from the GI tract
D. Compensatory increase in monoamine oxidase activity
4. The Blood-Brain Barrier (BBB) is formed primarily by:
A. Astrocytes
B. Microglia
C. Tight junctions between endothelial cells
D. Oligodendrocytes
, 5. A patient's "pharmacokinetics" refers to:
A. The mechanism of action of a drug at its receptor site
B. The time it takes for a drug to produce a clinical effect
C. What the body does to the drug (absorption, distribution, metabolism,
excretion)
D. The therapeutic and adverse effects of a drug
Depressive Disorders
6. Which of the following is a key consideration when prescribing an
SSRI?
A. Requires dietary tyramine restriction
B. Risk of hyperglycemia and dyslipidemia
C. Must be administered in divided doses to avoid sedation
D. Must monitor for activation or increased suicidal ideation, especially
in the first few weeks
EXAM 2025/2026 – VERIFIED QUESTIONS AND
ANSWERS
|| 100% GUARANTEED PASS
<UPDATED VERSION>
Neurobiology and Foundations of Psychopharmacology
1. The primary therapeutic effect of SSRIs is achieved through:
A. Blocking dopamine D2 receptors
B. Inhibiting the reuptake of serotonin in the synaptic cleft
C. Antagonizing NMDA glutamate receptors
D. Enhancing GABAergic inhibition
2. Which neurotransmitter system is most directly implicated in the
positive symptoms of schizophrenia?
,A. Serotonin (5-HT)
B. Norepinephrine (NE)
C. Dopamine (DA)
D. Acetylcholine (ACh)
3. The therapeutic lag often seen when initiating an SSRI is most
likely due to:
A. Immediate downregulation of post-synaptic receptors
B. The time required for downregulation of pre-synaptic autoreceptors
and subsequent increased serotonin release
C. Slow absorption from the GI tract
D. Compensatory increase in monoamine oxidase activity
4. The Blood-Brain Barrier (BBB) is formed primarily by:
A. Astrocytes
B. Microglia
C. Tight junctions between endothelial cells
D. Oligodendrocytes
, 5. A patient's "pharmacokinetics" refers to:
A. The mechanism of action of a drug at its receptor site
B. The time it takes for a drug to produce a clinical effect
C. What the body does to the drug (absorption, distribution, metabolism,
excretion)
D. The therapeutic and adverse effects of a drug
Depressive Disorders
6. Which of the following is a key consideration when prescribing an
SSRI?
A. Requires dietary tyramine restriction
B. Risk of hyperglycemia and dyslipidemia
C. Must be administered in divided doses to avoid sedation
D. Must monitor for activation or increased suicidal ideation, especially
in the first few weeks
