NURS 3335 FINAL PAPER 2025/2026 QUESTIONS AND
SOLUTION RATED A+
✔✔What type of fluid is 3% Sodium Chloride? - ✔✔Hypertonic
✔✔What is 3% Saline used for? - ✔✔Treat severe hyponatremia, reduce cerebral
edema
✔✔What are side effects of 3% Saline? - ✔✔Seizures (if too rapid), fluid overload,
hypernatremia
✔✔What are nursing considerations for 3% Saline? - ✔✔Give via central line, monitor
Na⁺ and neuro status, infuse slowly
✔✔What type of fluid is Dextrose 5% in Water (D5W)? - ✔✔Isotonic (becomes
hypotonic in the body)
✔✔What is D5W used for? - ✔✔Free water replacement, hypernatremia, calorie
supplementation
✔✔What are side effects of D5W? - ✔✔Hyperglycemia, cerebral edema, fluid overload
✔✔What are nursing considerations for D5W? - ✔✔Monitor blood glucose, avoid in
resuscitation or ↑ ICP
✔✔What are alarming effects of Duloxetine? - ✔✔Suicidal ideation, serotonin
syndrome, seizures, hypertension, urinary retention
✔✔What should patients avoid while taking Duloxetine? - ✔✔Alcohol, grapefruit juice,
abrupt discontinuation, St. John's wort
✔✔What are alarming effects of Fluoxetine? - ✔✔Suicidal ideation, serotonin syndrome
✔✔How long does it take for Fluoxetine to reach full effect? - ✔✔2-4 weeks
✔✔What should patients avoid while taking Fluoxetine? - ✔✔Alcohol, grapefruit juice,
abrupt discontinuation, St. John's wort
✔✔What receptors are blocked by Amitriptyline? - ✔✔Alpha, histamine, and muscarinic
receptors
✔✔What anticholinergic side effects are associated with Amitriptyline? - ✔✔Dry mouth,
dry eyes, blurred vision, constipation, urinary retention
, ✔✔What are alarming effects of Amitriptyline? - ✔✔Cardiotoxicity, EPS, NMS, seizures,
suicidal ideation
✔✔What foods should be avoided with MAOIs? - ✔✔Aged cheese, avocados, bananas,
red wine, salami, chocolate, caffeine
✔✔What medications should be avoided with MAOIs? - ✔✔OTC cold meds with
phenylephrine or pseudoephedrine, CNS stimulants
✔✔What is the required washout period for MAOIs before starting a new med? - ✔✔At
least 2 weeks
✔✔What are positive symptoms of schizophrenia? - ✔✔Hallucinations, delusions,
disorganized thinking
✔✔What are negative symptoms of schizophrenia? - ✔✔Flat affect, social withdrawal,
lack of motivation
✔✔Why are 2nd generation antipsychotics preferred? - ✔✔They treat both positive and
negative symptoms with fewer EPS
✔✔What does isotonic fluid do? - ✔✔Expands intravascular volume without shifting fluid
between compartments
✔✔What does hypotonic fluid do? - ✔✔Shifts fluid into cells to treat intracellular
dehydration
✔✔What does hypertonic fluid do? - ✔✔Pulls fluid out of cells to reduce cerebral edema
or treat hyponatremia
✔✔What is special about D5W? - ✔✔It starts isotonic but becomes hypotonic once
dextrose is metabolized
✔✔What is the suffix for antihistamines? - ✔✔-amine; -adine
✔✔What are examples of first and second generation antihistamines? -
✔✔Diphenhydramine (1st gen), Loratadine (2nd gen)
✔✔What are antihistamines used for? - ✔✔Seasonal allergies, rhinitis, conjunctivitis,
urticaria, insomnia, motion sickness
✔✔What is the MOA of antihistamines? - ✔✔Block histamine receptors to reduce
allergic symptoms, cause bronchodilation and vasoconstriction
SOLUTION RATED A+
✔✔What type of fluid is 3% Sodium Chloride? - ✔✔Hypertonic
✔✔What is 3% Saline used for? - ✔✔Treat severe hyponatremia, reduce cerebral
edema
✔✔What are side effects of 3% Saline? - ✔✔Seizures (if too rapid), fluid overload,
hypernatremia
✔✔What are nursing considerations for 3% Saline? - ✔✔Give via central line, monitor
Na⁺ and neuro status, infuse slowly
✔✔What type of fluid is Dextrose 5% in Water (D5W)? - ✔✔Isotonic (becomes
hypotonic in the body)
✔✔What is D5W used for? - ✔✔Free water replacement, hypernatremia, calorie
supplementation
✔✔What are side effects of D5W? - ✔✔Hyperglycemia, cerebral edema, fluid overload
✔✔What are nursing considerations for D5W? - ✔✔Monitor blood glucose, avoid in
resuscitation or ↑ ICP
✔✔What are alarming effects of Duloxetine? - ✔✔Suicidal ideation, serotonin
syndrome, seizures, hypertension, urinary retention
✔✔What should patients avoid while taking Duloxetine? - ✔✔Alcohol, grapefruit juice,
abrupt discontinuation, St. John's wort
✔✔What are alarming effects of Fluoxetine? - ✔✔Suicidal ideation, serotonin syndrome
✔✔How long does it take for Fluoxetine to reach full effect? - ✔✔2-4 weeks
✔✔What should patients avoid while taking Fluoxetine? - ✔✔Alcohol, grapefruit juice,
abrupt discontinuation, St. John's wort
✔✔What receptors are blocked by Amitriptyline? - ✔✔Alpha, histamine, and muscarinic
receptors
✔✔What anticholinergic side effects are associated with Amitriptyline? - ✔✔Dry mouth,
dry eyes, blurred vision, constipation, urinary retention
, ✔✔What are alarming effects of Amitriptyline? - ✔✔Cardiotoxicity, EPS, NMS, seizures,
suicidal ideation
✔✔What foods should be avoided with MAOIs? - ✔✔Aged cheese, avocados, bananas,
red wine, salami, chocolate, caffeine
✔✔What medications should be avoided with MAOIs? - ✔✔OTC cold meds with
phenylephrine or pseudoephedrine, CNS stimulants
✔✔What is the required washout period for MAOIs before starting a new med? - ✔✔At
least 2 weeks
✔✔What are positive symptoms of schizophrenia? - ✔✔Hallucinations, delusions,
disorganized thinking
✔✔What are negative symptoms of schizophrenia? - ✔✔Flat affect, social withdrawal,
lack of motivation
✔✔Why are 2nd generation antipsychotics preferred? - ✔✔They treat both positive and
negative symptoms with fewer EPS
✔✔What does isotonic fluid do? - ✔✔Expands intravascular volume without shifting fluid
between compartments
✔✔What does hypotonic fluid do? - ✔✔Shifts fluid into cells to treat intracellular
dehydration
✔✔What does hypertonic fluid do? - ✔✔Pulls fluid out of cells to reduce cerebral edema
or treat hyponatremia
✔✔What is special about D5W? - ✔✔It starts isotonic but becomes hypotonic once
dextrose is metabolized
✔✔What is the suffix for antihistamines? - ✔✔-amine; -adine
✔✔What are examples of first and second generation antihistamines? -
✔✔Diphenhydramine (1st gen), Loratadine (2nd gen)
✔✔What are antihistamines used for? - ✔✔Seasonal allergies, rhinitis, conjunctivitis,
urticaria, insomnia, motion sickness
✔✔What is the MOA of antihistamines? - ✔✔Block histamine receptors to reduce
allergic symptoms, cause bronchodilation and vasoconstriction
