Pathophysiology basic latest updated
questions and answers solution
The effects of vasodilation during an inflammatory response cause which of the
following? - Slower blood viscosity
Which of the following is a role of histamine when released by mast cells? - Increased
Vascular Permeability
Which of the following results when histamine attaches to the H1 receptor? - Smooth
muscle contraction, increased chemotaxis, stimulation of prostaglandin synthesis
Which chemical mediator is responsible for prolonged asthma symptoms such as
bronchoconstriction and inflammation? - Leukotrienes
Which of the following are an active modulator of allergic reactions in the immune
system? - Eosinophils
directs movement of cells along a chemical gradient attracting eosinophils and
neutrophils to the site of inflammation. - Chemotaxis
What are the functions of interferons? - Protect against viral infection, modulate
inflammatory response
Your patient has seasonal allergic rhinitis. Which type of hypersensitivity reaction is
this? - Type 1
Your patient has diagnosis of Grave's disease. Which type of Hypersensitivity reaction
is this? - Type 2
Which of the following is a type III hypersensitivity reaction? - Glomerulonephritis
Which of the following statement is true regarding Type IV Reactions? - The reaction is
mediated by T lymphocytes
Which of the following statements are true regarding exotoxins? - damage cell
membranes, activate second messengers, inhibit protein synthesis
immunity is produced by an individual after natural exposure to an antigen or after
immunization - Active
, immunity produces immunoglobulins that bind to antigens and neutralize their effects -
Humoral
stimulates the proliferation of T cells and B cells during inflammation - Interleukins
Catecholamines decrease which of the following immune system cells during chronic
stress? - Natural Killer cells
interfere with insulin signaling leading to insulin resistance in stress, obesity, and Type 2
Diabetes. - Pro-inflammatory cytokines
what type of immunity is produced when an immunoglobulin crosses the placenta? -
Passive acquired
the normal microbiome - The body's surfaces are colonized with a variety of
microorganisms, Surfaces, such as skin and mucous membranes of eyes, upper and
lower GI tracts, urethra and vagina are colonized by a combination of bacteria and fungi
that are unique to a particular location and individual.
If immunocompromised the microbiome can lead to - opportunistic infections or loss of
integrity of the body surface areas.
Type 1 hypersensitivity example - seasonal rhinitis
Type 1 hypersensitivity - IgE mediated, binds to mast cell which causes release of
histamine and other inflammatory cytokines
Eosinphils are active in which hypersensitivity? - Type 1
Histamine binds to _ to cause allergic reaction - H1 receptors
Where are H1 receptors found? - smooth muscle, endothelium, bronchial lining, oral
mucosa
act to prevent over reactions in the smooth muscle contractions brought on by histamine
binding to H1 receptors - H2 receptors
histamine binding to H1 causes - smooth muscle contraction
histamine binding to H2 causes - smooth muscle relaxation, avoids anaphylaxis
H2 blocker examples - pepcid
H1 is - pro-inflammatory
H2 is - antiinflammatory