Final Exam Test Questions
Study online at https://quizlet.com/_9m1zl2
1. Question 18:
Christine is a 9-year-old female who presents for care after having been placed
in the local foster care system. She has been in and out of foster care for the last
4 years after her parents were killed in an automobile accident. Christine has
been placed in a variety of homes and residential care facilities. The PMHNP
recognizes that Christine is at high risk for:: A. Dissociative disorders
B. Post-traumatic stress disorder
C. Impulse-control disorder
D. Attachment disorder
2. Question 7:
Caylee is a 5-year-old girl who is referred for evaluation by child protective
services. She was recently removed from her biological family and placed in
foster care, as her home environment was reportedly unsafe due to conditions
of extreme neglect. Her foster mother reports that Caylee is very quiet and
withdrawn and always appears sad and disinterested in her surroundings;
however, she becomes very irritable when anything unexpected or unplanned
occurs. The foster mother became very concerned when it appeared that
Caylee was hallucinating. The PMHNP considers that:: A. Caylee is at high risk for suicide
and precautions should be taken
B. The hallucinations are consistent with brief psychotic disorder or schizophrenia
C. The history and reported symptoms are typical of depressive disorder in young children
D. This is a common situation when prepubertal children are removed from the biological parents regardless of how
dysfunctional they are
3. Question 2:
Debi is a 15-year-old girl who is currently being treated for depression. Her
parents have been very proactive and involved in her care, and Debi has
achieved remission 2 months after beginning treatment with a combination of
pharmacotherapy and cognitive behavioral therapy. While counseling Debi's
parents about important issues in management, the PMHNP advises that:: A.
There is a > 50% likelihood that Debi's younger sibling will develop depressive symptoms
B. The mean length of major depressive episode in adolescents is 4 months
, Final Exam Test Questions
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C. 20 to 40% of adolescents who have major depressive disorder will develop bipolar I within 5 years
D. Adolescent-onset depression typically need long-term pharmacologic management to prevent relapses
4. Agomelatine: Brand: Valdoxan
-Melatonin multimodal (Mel-MM)
-Agonist at melatonergic 1 and melatonergic 2 receptors
-Antagonist at 5HT2C receptors
-Not FDA approved: Rx for Depression, Generalized anxiety disorder
-Initial 25 mg/day at bedtime; after 2 weeks can increase to 50 mg/day at bedtime
5. Amitriptyline (Elavil): Tricyclic antidepressant.
6. Aripiprazole (Abilify): Treatment for depression. Atypical antipsychotic. "Dopamine stabilizer". Dopamine
receptor antagonist in high concentration and also stimulates increase of dopamine in low concentrations. Side effects:
insomnia, akathisia.
7. Brexpiprazole (Rexulti): Treatment for depression. Atypical antipsychotic
8. Bupropion (Wellbutrin): Antidepressant and smoking cessation aid, It can treat depression and help
people quit smoking. It can also prevent depression caused by seasonal affective disorder (SAD).
9. Citalopram (Celexa): Antidepressant, SSRI: 20-40 mg qd.
10. Clomipramine (Anafranil): -Serotonin reuptake inhibitor (S-RI)
-Tricyclic antidepressant (TCA)
-Parent drug is a potent serotonin reuptake inhibitor
Active metabolite is a potent norepinephrine/noradrenaline reuptake inhibitor
-Increases serotonergic neurotransmission by blocking the serotonin reuptake pump (transporter), -Desensitization of
serotonin receptors, especially serotonin 1A receptors
-Increases noradrenergic neurotransmission by blocking the norepinephrine reuptake pump (transporter), -Desensi-
tization of beta adrenergic receptors
-Dopamine is inactivated by norepinephrine reuptake in the frontal cortex
-Lacks dopamine transporters
-Increases dopamine neurotransmission in this part of the brain
**FDA Approved for Pediatrics in tx Obsessive-compulsive disorder (OCD) (ages 10 and older)
*Off-Label for Pediatric Use: Depression, Severe and treatment-resistant, depression, Cataplexy syndrome, Anxiety,
Insomnia,
Neuropathic pain/chronic pain
-Full therapeutic benefits may take 2-8 weeks
, Final Exam Test Questions
Study online at https://quizlet.com/_9m1zl2
-Dosing: in Peds/Adolescents/Adults:
100-250mg/day
11. Cyamemazine (Tercian): Treatment for depression.
-Known as cyamepromazine
-Typical antipsychotic drug of the phenothiazine class.
-Treatment for schizophrenia
and psychosis-associated
anxiety
-Behaves like an atypical
antipsychotic, due to its
potent anxiolytic effects (5-HT2C) and lack of extrapyramidal side effects (5-HT2A).
-Conventional antipsychotic (neuroleptic, phenothiazine, dopamine 2 antagonist, serotonin dopamine antagonist)
-Commonly Prescribed for (not FDA approved):
-Schizophrenia
-Anxiety associated with psychosis (short-term)
-Anxiety associated with nonpsychotic disorders, including mood disorders and personality disorders (short-term)
-Severe depression
-Bipolar disorder
-Other psychotic disorders
-Acute agitation/aggression (injection)
-Benzodiazepine withdrawal
12. Desiprimine (Norpramine): Treats depression
Brand: Norpramin
-TCA
-Norepinephrine noradrenaline reuptake inhibitor.
-FDA approved for treating depression.
-Off-label: Anxiety, Insomnia,
Neuropathic pain/chronic pain, Treatment-resistant depression.
-More potent inhibitor of norepinephrine reuptake pump than serotonin reuptake pump (serotonin transporter).
-May have immediate effects in treating insomnia or anxiety.
-If it is not working within 6-8 weeks for depression, it may require a dosage increase or it may not work at all
, Final Exam Test Questions
Study online at https://quizlet.com/_9m1zl2
-100-200 mg/day (for depression)
50-150 mg/day (for chronic pain).
13. Desvenlafaxine (Pristiq): Dual serotonin and norepinephrine reuptake inhibitor-often classified as an
antidepressant.
-FDA approved to tx MDD.
-Off-label: Vasomotor sx's, fibromyalgia, GAD, Social Anx d/o, panic d/o, PTSD, PMDD
-Dopamine is inactivated by norepinephrine reuptake in frontal cortex (which lack dopamine transporters) med can
increase dopamine neurotransmission in this part of the brain
-
14. Risperidone (Risperdal): Atypical Antipsychotic (most "typical" of atypicals)
Side effects: EPS (dose-dependent), TD, significant increases in PRL (check PRL levels)
--> most dopaminergic of Atypicals
IM formulation is available
15. Amphetamines: drugs that stimulate neural activity, causing speeded-up body functions and associated
energy and mood changes
16. Dextroamphetamine: CNS stimulant
*Mech*: Inc catecholamines at the synaptic cleft, especially NE and dopamine.
*Use*: ADHD, narcolepsy, apetite control
17. Atomoxetine (Strattera): - BBW
> Risk of suicidal ideation; monitor for suicidal thinking or behavior, worsening, or unusual behavior
- Contraindications
> Glaucoma, pheochromocytoma, MAO I use within past 14 days
- Warning
> Rare, but severe hepatotoxicity (most within 120 days of start of treatment)
SE
> Headache, insomnia, *somnolence*, dry mouth, nausea, abdominal pain, decrease in appetite, nausea, etc.
> Priapism
NOTE
> * do not open capsule * - irritant
> CYPD 2D6 substrate
> watch out for *LIVER PROBLEMS *
Study online at https://quizlet.com/_9m1zl2
1. Question 18:
Christine is a 9-year-old female who presents for care after having been placed
in the local foster care system. She has been in and out of foster care for the last
4 years after her parents were killed in an automobile accident. Christine has
been placed in a variety of homes and residential care facilities. The PMHNP
recognizes that Christine is at high risk for:: A. Dissociative disorders
B. Post-traumatic stress disorder
C. Impulse-control disorder
D. Attachment disorder
2. Question 7:
Caylee is a 5-year-old girl who is referred for evaluation by child protective
services. She was recently removed from her biological family and placed in
foster care, as her home environment was reportedly unsafe due to conditions
of extreme neglect. Her foster mother reports that Caylee is very quiet and
withdrawn and always appears sad and disinterested in her surroundings;
however, she becomes very irritable when anything unexpected or unplanned
occurs. The foster mother became very concerned when it appeared that
Caylee was hallucinating. The PMHNP considers that:: A. Caylee is at high risk for suicide
and precautions should be taken
B. The hallucinations are consistent with brief psychotic disorder or schizophrenia
C. The history and reported symptoms are typical of depressive disorder in young children
D. This is a common situation when prepubertal children are removed from the biological parents regardless of how
dysfunctional they are
3. Question 2:
Debi is a 15-year-old girl who is currently being treated for depression. Her
parents have been very proactive and involved in her care, and Debi has
achieved remission 2 months after beginning treatment with a combination of
pharmacotherapy and cognitive behavioral therapy. While counseling Debi's
parents about important issues in management, the PMHNP advises that:: A.
There is a > 50% likelihood that Debi's younger sibling will develop depressive symptoms
B. The mean length of major depressive episode in adolescents is 4 months
, Final Exam Test Questions
Study online at https://quizlet.com/_9m1zl2
C. 20 to 40% of adolescents who have major depressive disorder will develop bipolar I within 5 years
D. Adolescent-onset depression typically need long-term pharmacologic management to prevent relapses
4. Agomelatine: Brand: Valdoxan
-Melatonin multimodal (Mel-MM)
-Agonist at melatonergic 1 and melatonergic 2 receptors
-Antagonist at 5HT2C receptors
-Not FDA approved: Rx for Depression, Generalized anxiety disorder
-Initial 25 mg/day at bedtime; after 2 weeks can increase to 50 mg/day at bedtime
5. Amitriptyline (Elavil): Tricyclic antidepressant.
6. Aripiprazole (Abilify): Treatment for depression. Atypical antipsychotic. "Dopamine stabilizer". Dopamine
receptor antagonist in high concentration and also stimulates increase of dopamine in low concentrations. Side effects:
insomnia, akathisia.
7. Brexpiprazole (Rexulti): Treatment for depression. Atypical antipsychotic
8. Bupropion (Wellbutrin): Antidepressant and smoking cessation aid, It can treat depression and help
people quit smoking. It can also prevent depression caused by seasonal affective disorder (SAD).
9. Citalopram (Celexa): Antidepressant, SSRI: 20-40 mg qd.
10. Clomipramine (Anafranil): -Serotonin reuptake inhibitor (S-RI)
-Tricyclic antidepressant (TCA)
-Parent drug is a potent serotonin reuptake inhibitor
Active metabolite is a potent norepinephrine/noradrenaline reuptake inhibitor
-Increases serotonergic neurotransmission by blocking the serotonin reuptake pump (transporter), -Desensitization of
serotonin receptors, especially serotonin 1A receptors
-Increases noradrenergic neurotransmission by blocking the norepinephrine reuptake pump (transporter), -Desensi-
tization of beta adrenergic receptors
-Dopamine is inactivated by norepinephrine reuptake in the frontal cortex
-Lacks dopamine transporters
-Increases dopamine neurotransmission in this part of the brain
**FDA Approved for Pediatrics in tx Obsessive-compulsive disorder (OCD) (ages 10 and older)
*Off-Label for Pediatric Use: Depression, Severe and treatment-resistant, depression, Cataplexy syndrome, Anxiety,
Insomnia,
Neuropathic pain/chronic pain
-Full therapeutic benefits may take 2-8 weeks
, Final Exam Test Questions
Study online at https://quizlet.com/_9m1zl2
-Dosing: in Peds/Adolescents/Adults:
100-250mg/day
11. Cyamemazine (Tercian): Treatment for depression.
-Known as cyamepromazine
-Typical antipsychotic drug of the phenothiazine class.
-Treatment for schizophrenia
and psychosis-associated
anxiety
-Behaves like an atypical
antipsychotic, due to its
potent anxiolytic effects (5-HT2C) and lack of extrapyramidal side effects (5-HT2A).
-Conventional antipsychotic (neuroleptic, phenothiazine, dopamine 2 antagonist, serotonin dopamine antagonist)
-Commonly Prescribed for (not FDA approved):
-Schizophrenia
-Anxiety associated with psychosis (short-term)
-Anxiety associated with nonpsychotic disorders, including mood disorders and personality disorders (short-term)
-Severe depression
-Bipolar disorder
-Other psychotic disorders
-Acute agitation/aggression (injection)
-Benzodiazepine withdrawal
12. Desiprimine (Norpramine): Treats depression
Brand: Norpramin
-TCA
-Norepinephrine noradrenaline reuptake inhibitor.
-FDA approved for treating depression.
-Off-label: Anxiety, Insomnia,
Neuropathic pain/chronic pain, Treatment-resistant depression.
-More potent inhibitor of norepinephrine reuptake pump than serotonin reuptake pump (serotonin transporter).
-May have immediate effects in treating insomnia or anxiety.
-If it is not working within 6-8 weeks for depression, it may require a dosage increase or it may not work at all
, Final Exam Test Questions
Study online at https://quizlet.com/_9m1zl2
-100-200 mg/day (for depression)
50-150 mg/day (for chronic pain).
13. Desvenlafaxine (Pristiq): Dual serotonin and norepinephrine reuptake inhibitor-often classified as an
antidepressant.
-FDA approved to tx MDD.
-Off-label: Vasomotor sx's, fibromyalgia, GAD, Social Anx d/o, panic d/o, PTSD, PMDD
-Dopamine is inactivated by norepinephrine reuptake in frontal cortex (which lack dopamine transporters) med can
increase dopamine neurotransmission in this part of the brain
-
14. Risperidone (Risperdal): Atypical Antipsychotic (most "typical" of atypicals)
Side effects: EPS (dose-dependent), TD, significant increases in PRL (check PRL levels)
--> most dopaminergic of Atypicals
IM formulation is available
15. Amphetamines: drugs that stimulate neural activity, causing speeded-up body functions and associated
energy and mood changes
16. Dextroamphetamine: CNS stimulant
*Mech*: Inc catecholamines at the synaptic cleft, especially NE and dopamine.
*Use*: ADHD, narcolepsy, apetite control
17. Atomoxetine (Strattera): - BBW
> Risk of suicidal ideation; monitor for suicidal thinking or behavior, worsening, or unusual behavior
- Contraindications
> Glaucoma, pheochromocytoma, MAO I use within past 14 days
- Warning
> Rare, but severe hepatotoxicity (most within 120 days of start of treatment)
SE
> Headache, insomnia, *somnolence*, dry mouth, nausea, abdominal pain, decrease in appetite, nausea, etc.
> Priapism
NOTE
> * do not open capsule * - irritant
> CYPD 2D6 substrate
> watch out for *LIVER PROBLEMS *
